Best Practice and Research. Clinical Gastroenterology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Colorectal cancer prevention in patients with ulcerative colitis
Publication date: February–April 2018Source: Best Practice & Research Clinical Gastroenterology, Volumes 32–33Author(s): Anthony Lopez, Lieven Pouillon, Laurent Beaugerie, Silvio Danese, Laurent Peyrin-BirouletAbstractUlcerative colitis is characterized by chronic inflammation, which may lead to the accumulation of high levels of pro-inflammatory cytokines within the colonic mucosa, and thus to dysplastic lesions and cancer. Although the trend is decreasing, ulcerative colitis patients still have a 2.4 fold higher risk of colorectal cancer compared to the general population. The key task is to control colonic inflammat...
Source: Best Practice and Research Clinical Gastroenterology - July 28, 2018 Category: Gastroenterology Source Type: research
Editorial Board
Publication date: February–April 2018Source: Best Practice & Research Clinical Gastroenterology, Volumes 32–33Author(s): (Source: Best Practice and Research Clinical Gastroenterology)
Source: Best Practice and Research Clinical Gastroenterology - July 28, 2018 Category: Gastroenterology Source Type: research
Evolving strategies and goals of treatment in ulcerative colitis
Publication date: February–April 2018Source: Best Practice & Research Clinical Gastroenterology, Volumes 32–33Author(s): Mariangela Allocca, Laurent Peyrin-Biroulet, Silvio Danese (Source: Best Practice and Research Clinical Gastroenterology)
Source: Best Practice and Research Clinical Gastroenterology - July 28, 2018 Category: Gastroenterology Source Type: research
Alcohol, smoking and the GI tract
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Stephen McCain, Helen G. Coleman (Source: Best Practice and Research Clinical Gastroenterology)
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Communication of alcohol and smoking lifestyle advice to the gastroenterological patient
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Andrew D. Spence, Mais Khasawneh, Patrick B. Allen, Jennifer AddleyAbstractEffective communication between healthcare staff and patients is central to development of the patient-professional relationship. Many barriers influence this communication, often resulting in patients' lack of understanding and retention of information, particularly affecting advice regarding lifestyle habits, such as alcohol consumption and smoking. Alcohol and smoking misuse are potentially modifiable risk factors known to advers...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Impact of alcohol & smoking on the surgical management of gastrointestinal patients
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Niall D. Kennedy, Des C. WinterAbstractAlcohol and smoking are repeatedly described as modifiable risk factors in clinical studies across all surgical specialities. These lifestyle choices impart a sub-optimal physiology via multiple processes and play an important role in the surgical management of the gastrointestinal patient. Cessation is imperative to optimise the patient's fitness for surgery with surgery itself being a prime opportunity for sustained cessation. A consistent, planned and integrated ma...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The interaction between smoking, alcohol and the gut microbiome
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Gabriele Capurso, Edith LahnerAbstractThe gastrointestinal microbiome is a complex echosystem that establishes a symbiotic, mutually beneficial relation with the host, being rather stable in health, but affected by age, drugs, diet, alcohol, and smoking. Alcohol and smoking contribute to changes in the stomach and affect H pylori-related disorders including the risk of gastric cancer. In the small intestine and in the colon alcohol causes depletion of bacteria with anti-inflammatory activity, eventually re...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Do smoking and alcohol behaviours influence GI cancer survival?
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Úna C. McMenamin, Stephen McCain, Andrew T. KunzmannAbstractLittle is known about the role of alcohol and smoking in GI cancer survival compared to GI cancer development. We systematically reviewed the evidence for a role of smoking and alcohol in prognosis among GI cancer patients and inform whether smoking or alcohol cessation interventions or guidelines for GI cancer patients are likely to improve prognosis. A total of 84 relevant studies were identified. Continued smokers, particularly heavy smokers, ...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Alcohol, smoking and the risk of premalignant and malignant colorectal neoplasms
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Ifewumi O. Fagunwa, Maurice B. Loughrey, Helen G. ColemanAbstractColorectal cancer (CRC) is the third most common cancer worldwide and has a complex aetiology consisting of environmental and genetic factors. In this review, we evaluate the roles of alcohol and tobacco smoking in colorectal neoplasia. Alcohol intake and tobacco smoking are associated with modest, but significantly, increased risks of CRC, adenomatous and serrated polyps. There is consistent evidence of dose-response relationships for both a...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The role of smoking and alcohol behaviour in the management of inflammatory bowel disease
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Mais Khasawneh, Andrew D. Spence, Jennifer Addley, Patrick B. AllenAbstractIn the era of increasing use of immunosuppressive and biologic therapy for inflammatory bowel disease, environmental influences remain important independent risk factors to modify the course of the disease, affect the need for surgery and recurrence rates post-surgical resection. The effect of smoking on inflammatory bowel disease has been established over the decades, however the exact mechanism of how smoking affects remains as ar...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Key role of local acetaldehyde in upper GI tract carcinogenesis
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Mikko SalaspuroAbstractEthanol is neither genotoxic nor mutagenic. Its first metabolite acetaldehyde, however, is a powerful local carcinogen. Point mutation in ALDH2 gene proves the causal relationship between acetaldehyde and upper digestive tract cancer in humans. Salivary acetaldehyde concentration and exposure time are the two major and quantifiable factors regulating the degree of local acetaldehyde exposure in the ideal target organ, oropharynx. Instant microbial acetaldehyde formation from alcohol ...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Alcohol, smoking and the liver disease patient
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Hannes HagströmAbstractAlcohol is an established risk factor for cirrhosis. Current recommendations for a “safe” limit for alcohol consumption are usually set to around 30 g of alcohol per day for men and 20 g per day for women, but evidence is mounting that these cut-offs might be set too high. Also, inter-individual differences in the hepatic sensitivity for alcohol likely play into the risk of development of cirrhosis. In patients with concomitant liver diseases, a synergistic effect on fibrosis ...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Tobacco and alcohol as risk factors for pancreatic cancer
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Murray Korc, Christie Y. Jeon, Mouad Edderkaoui, Stephen J. Pandol, Maxim S. Petrov, on behalf of the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer (CPDPC)AbstractPancreatic cancer is projected to become the leading cause of cancer deaths by 2050. The risk for pancreatic cancer may be reduced by up to 27% by modifying lifestyle risk factors, most notably tobacco smoking. Based on analysis of more than 2 million unselected individuals from general population, this article...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Alcohol, smoking and benign hepato-biliary disease
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Daniel Mønsted Shabanzadeh, Srdan NovovicAbstractGallstone disease and pancreatitis are the most frequent benign hepato-biliary causes of hospital admissions. Gallstone disease is prevalent, but symptomatic disease develops only in about one out of five carriers. Alcohol intake seems to protect gallstone formation in cohort studies possibly through effects on bile cholesterol metabolism, the enterohepatic circulation, and gallbladder function. The impact of smoking on gallstone formation seems minor. Both...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Alcohol, smoking and risk of oesophago-gastric cancer
Publication date: October 2017Source: Best Practice & Research Clinical Gastroenterology, Volume 31, Issue 5Author(s): Jing Dong, Aaron P. ThriftAbstractOesophago-gastric cancers (oesophageal and gastric cancers) are common, highly fatal cancers. Oesophageal squamous cell carcinoma (OSCC) and oesophageal adenocarcinoma (OAC) are the two main histological subtypes of oesophageal cancer. Globally, OSCC remains the most common histological subtype of oesophageal cancer, with the highest burden occurring along two geographic belts, one from north central China through the central Asian republics to northern Iran, and one from ...
Source: Best Practice and Research Clinical Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
