Best Practice and Research. Clinical Endocrinology and Metabolism This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Single embryo transfer: why and how to identify the embryo with the best developmental potential
Publication date: Available online 13 April 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Aila TiitinenAbstractMultiple pregnancies with higher risk of preterm birth and the associated higher morbidity have been a major obstacle from the early days of in vitro fertilization. A good strategy to avoid multiple pregnancies is elective single embryo transfer and cryopreservation of spare embryos. Important factors in adopting this strategy are good counselling of the patients and the selection of embryos with high implantation potential. Technical advances in embryo selection have been desc...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 14, 2019 Category: Endocrinology Source Type: research

Peripheral Precocious Puberty including congenital adrenal hyperplasia: causes, consequences, management and outcomes
Publication date: Available online 13 April 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Nadine G. Haddad, Erica A. EugsterAbstractPeripheral precocious puberty results from peripheral production of sex steroids independent of activation of the hypothalamic-pituitary gonadal axis. It is much less common than central precocious puberty. Causes are variable and can be congenital or acquired. In this review, we will discuss the diagnosis and management of the most common etiologies including congenital adrenal hyperplasia, McCune Albright syndrome, familial male-limited precocious puberty...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 14, 2019 Category: Endocrinology Source Type: research

Preface
Publication date: Available online 1 April 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Christian De Geyter (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - April 3, 2019 Category: Endocrinology Source Type: research

Normal physiology (brief overview)
Publication date: Available online 30 March 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Claire Wood, Laura C. Lane, Tim CheethamAbstractPuberty is a defining phase of human development where growth ends and the ability to reproduce begins. An understanding of the events leading up to puberty highlights the fact that this is the culmination of a process of skeletal and gonadal activity that has been ongoing since conception. Although there is natural variation in the timing of events in and around puberty the basic underlying processes are common to all healthy human beings. This chapt...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 30, 2019 Category: Endocrinology Source Type: research

National acromegaly registries
In conclusion, acromegaly registries offer a global view of the disease with no “a priori” assumptions. This is of outmost importance, because of the large amount of data and the huge number of associated comorbidities. This will help to establish guidelines for management of this rare disease. (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - March 7, 2019 Category: Endocrinology Source Type: research

Assisted reproductive technology: impact on society and need for surveillance
Publication date: Available online 25 January 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Christian De Geyter (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 26, 2019 Category: Endocrinology Source Type: research

Central Precocious Puberty, Functional And Tumor-Related
Publication date: Available online 22 January 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Leandro Soriano-Guillén, Jesús ArgenteAbstractPrecocious puberty is defined as the appearance of secondary sex characteristics before 8 years of age in girls and before 9 years of age in boys. Central precocious puberty (CPP) is diagnosed when activation of the hypothalamic-pituitary axis is identified. It is a rare disease with a clear female predominance. A background of international adoption increases its risk, with other environmental factors such as endocrine disruptors also being associa...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 23, 2019 Category: Endocrinology Source Type: research

IUGR: genetic influences, metabolic problems, environmental associations/triggers, current and future management
Publication date: Available online 22 January 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Feyza DarendelilerAbstractThe children with intrauterine growth retardation (IUGR) especially if they make a catch-up growth in early life have a higher risk for long term problems including short stature and also developing metabolic syndrome, Type 2 diabetes, insulin resistance and cardiovascular diseases. The studies also support that these children may have abnormalities in pubertal timing, adrenarche and reproductive function. The aim of this review was to summarize the published reports mai...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 23, 2019 Category: Endocrinology Source Type: research

Male fertility preservation in DSD, XXY, pre-gonadotoxic treatments – update, methods, ethical issues, current outcomes, future directions
Publication date: Available online 23 January 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Maria Grazia Giudice, Federico Del Vento, Christine WynsAbstractThis paper aims at reviewing the fertility preservation strategies that could be considered in several conditions at risk of spermatogonial depletion such as 46,XY disorders of sexual development, Klinefelter syndrome and after gonadotoxic treatment in males highlighting current knowledge on diseases and processes involved in infertility as well as future directions along with their specific ethical issues.While sperm cryopreservatio...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 23, 2019 Category: Endocrinology Source Type: research

Editorial Board
Publication date: December 2018Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 32, Issue 6Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - January 20, 2019 Category: Endocrinology Source Type: research

Treatment of hypoparathyroidism
Publication date: Available online 6 December 2018Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Francesco Tecilazich, Anna Maria Formenti, Stefano Frara, Raffaele Giubbini, Andrea GiustinaAbstractThe goal of the clinical management of hypoparathyroidism is to correct acute and chronic hypocalcemia. Treatment of acute hypoparathyroidism via intravenous infusion of Ca++ salts, is necessary only in symptomatic patients, or in asymptomatic patients in the setting of a rapid decrease in ionized Ca++ levels. The treatment cornerstones of chronic hypoparathyroidism are oral supplementation of calc...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 7, 2018 Category: Endocrinology Source Type: research

The surgical management of sporadic primary hyperparathyroidism
Publication date: Available online 6 December 2018Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Richard J. Egan, David M. Scott-CoombesAbstractSporadic primary hyperparathyroidism (pHPT) is the commonest cause of hypercalcaemia in the ambulatory population. It has a female preponderance and its incidence is increasing. In 85% of cases it is caused by a single parathyroid adenoma, with four gland hyperplasia in up to 20%. Parathyroidectomy is the only cure and bilateral neck exploration remains the gold standard to achieve this. Several adjuncts have been developed to improve success rates o...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 7, 2018 Category: Endocrinology Source Type: research

Epidemiology of Parathyroid Disorders
Publication date: Available online 7 December 2018Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sudhaker D. RaoAbstractParathyroid disorders are not as uncommon as once believed. Both hyper- and hyperparathyroidism are more prevalent in women, but for different reasons. The female preponderance in primary hyperparathyroidism may be pathogenically linked, as it is more common after menopause. By contrast, higher prevalence of hypoparathyroidism in women is related to thyroid surgery, which is performed more commonly in women; thus the female to male ratio of hyper- and hypoparathyroidism is ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 7, 2018 Category: Endocrinology Source Type: research

Parathyroid Carcinoma
Publication date: Available online 1 December 2018Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Antonio Stefano Salcuni, Filomena Cetani, Vito Guarnieri, Vincenzo Nicastro, Elisabetta Romagnoli, Danilo de Martino, Alfredo Scillitani, David EC. ColeAbstractParathyroid carcinoma (PC) is a rare disease with an indolent behavior due to the low malignant potential. The etiology is unknown. Somatic mutations of CDC73 gene, the same gene involved in the hyperparathyroidism-jaw tumor syndrome, can be identified in up to 70% of patients with PC and in one-third of cases the mutations are germline. T...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - December 2, 2018 Category: Endocrinology Source Type: research

Molecular pathogenesis of parathyroid tumours
Publication date: Available online 20 November 2018Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Luigia Cinque, Flavia Pugliese, Antonio Stefano Salcuni, Alfredo Scillitani, Vito GuarnieriAbstractParathyroid tumors represent an elusive endocrine neoplasia, which lead to primary hyperparathyroidism, pHPT, a common endocrine calcium disorder characterized by hypercalcemia and normal-high parathormone secretion. Parathyroid tumours are benign adenomas or multiple glands hyperplasia in the vast majority (>99% of cases), while malignant neoplasms are rare (less than 1%). Despite pHPT is a common...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - November 21, 2018 Category: Endocrinology Source Type: research