Peripheral Precocious Puberty including congenital adrenal hyperplasia: causes, consequences, management and outcomes

Publication date: Available online 13 April 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Nadine G. Haddad, Erica A. EugsterAbstractPeripheral precocious puberty results from peripheral production of sex steroids independent of activation of the hypothalamic-pituitary gonadal axis. It is much less common than central precocious puberty. Causes are variable and can be congenital or acquired. In this review, we will discuss the diagnosis and management of the most common etiologies including congenital adrenal hyperplasia, McCune Albright syndrome, familial male-limited precocious puberty, and adrenal and gonadal tumors.
Source: Best Practice and Research Clinical Endocrinology and Metabolism - Category: Endocrinology Source Type: research