Relationship Between Echocardiographically Evaluated Aortic Stiffness and Prolidase Activity in Aortic Tissue of Patients with Critical Coronary Artery Disease
The aim of this study was to determine the relationship between echocardiographically evaluated aortic stiffness and prolidase activity in aortic tissue of patients with critical coronary occlusion. (Source: Archives of Medical Research)
Source: Archives of Medical Research - July 3, 2016 Category: Research Authors: Aydemir Koçarslan, Sezen Koçarslan, Mehmet Salih Aydin, İbrahim Halil Altiparmak, Deniz Demir, Hatice Sezen, Hasan Hüsnü Yüce, Mustafa Göz Tags: Original Article Source Type: research
D-dimer Is a Predictor of 28-Day Mortality in Critically Ill Patients Receiving Continuous Renal Replacement Therapy
Continuous renal replacement therapy (CRRT) is an important treatment in the intensive care unit (ICU). Nevertheless, the outcome of CRRT remains unclear. It is important to find a useful and easy indicator to predict the prognosis in patients on CRRT treatment. We undertook this study to observe the association between serum D-dimer level and mortality of ICU patients in the treatment of CRRT. (Source: Archives of Medical Research)
Source: Archives of Medical Research - June 30, 2016 Category: Research Authors: Jun Lu, Xing Wang, Qiuhua Chen, Mingqi Chen, Lu Cheng, Hua Jiang, Zhiguang Sun Tags: Original Article Source Type: research
Relationship Between Serum microRNA155 and Telomerase Expression in Hepatocellular Carcinoma
Activation of telomerase reverse transcriptase (hTERT) has a role in liver carcinogenesis where telomerase is normally suppressed in most human somatic tissues after birth. In the current study we aimed to detect the significance of hTERT mRNA in early detection of hepatocellular carcinoma (HCC) and to determine the relationship between serum microRNA155 and telomerase expression. (Source: Archives of Medical Research)
Source: Archives of Medical Research - June 30, 2016 Category: Research Authors: Wafaa M. Ezzat, Khalda Said Amr, Haiam Abdel Raouf, Yasser A. Elhosary, Abdelfattah E. Hegazy, Hoda H. Fahim, Refaat R. Kamel Tags: Original Article Source Type: research
Diagnosis of Sepsis with Cell-free DNA by Next-Generation Sequencing Technology in ICU Patients
Bacteremia is a common serious manifestation of disease in the intensive care unit (ICU), which requires quick and accurate determinations of pathogens to select the appropriate antibiotic treatment. To overcome the shortcomings of traditional bacterial culture (BC), we have adapted next-generation sequencing (NGS) technology to identify pathogens from cell-free plasma DNA. (Source: Archives of Medical Research)
Source: Archives of Medical Research - June 30, 2016 Category: Research Authors: Yun Long, Yinxin Zhang, Yanping Gong, Ruixue Sun, Longxiang Su, Xin Lin, Ao Shen, Jiali Zhou, Zhuoma Caiji, Xinying Wang, Dongfang Li, Honglong Wu, Hongdong Tan Tags: Original Article Source Type: research
Monitoring of CD8(+) T-cell Activity in mTOR Inhibitor-treated Cancer Patients for Successful Immunotherapy
Mammalian target of rapamycin (mTOR) inhibitors are strong anti-tumor drugs; however, they have adverse immunosuppressive side effects in some cancer patients. Animal studies have provided evidence that mTOR inhibitors improved tumor-specific T-cells adoptive transfer in which the quality of CD8+ T-cells is a major factor for predicting success. Interestingly, mTOR inhibitors are capable of stimulating cytotoxic CD8+ T-cell if their dose/duration is adjusted. Rapamycin-induced CD8+ T-cells have also been associated with tumor immunity in animal models. (Source: Archives of Medical Research)
Source: Archives of Medical Research - June 30, 2016 Category: Research Authors: Alireza Bolourian, Zahra Mojtahedi Tags: Opinion Source Type: research
