Review of the role of robotic surgery in male infertility
ConclusionsRobotic assistance for microsurgical procedures in male infertility appears to be safe and feasible. It has several advantages including elimination of tremor, multi-view magnification, additional instrument arms, and enhanced dexterity with articulating instrument arms. It also has a short learning curve with a small skin incision. However, larger, prospective studies are needed to establish the clinical benefits over standard microsurgery. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Varicocele management for infertility and pain: A systematic review
Publication date: March 2018Source: Arab Journal of Urology, Volume 16, Issue 1Author(s): Scott D. Lundy, Edmund S. SabaneghAbstractDespite being first described two thousand years ago, the varicocele remains a controversial multifaceted disease process with numerous biological consequences including infertility, hypogonadism, and chronic orchidalgia. The underlying mechanisms remain poorly understood and likely include hypoxia, oxidative stress, hyperthermia, anatomical aberrations, and genetics as primary components. Despite a high prevalence amongst asymptomatic fertile men, varicoceles paradoxically also represent the ...
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Spermatogonial stem cell transplantation and male infertility: Current status and future directions
ConclusionsEvidence does not yet support clinical application of SSCs in humans. However, significant progress in the in vitro and in vivo development of SSCs, including differentiation into functional germ cells, gives reason for cautious optimism for future research. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Microscopic subinguinal varicocelectomy in 100 consecutive cases: Spermatic cord vascular anatomy, recurrence and hydrocele outcome analysis
ConclusionMicroscopic subinguinal varicocelectomy accurately evaluated the detailed vascular anatomy of the spermatic cord, achieving excellent surgical outcome with minimal varicocele recurrence and hydrocele formation. Microscopic subinguinal varicocelectomy should be the ‘gold standard’ for varicocelectomy. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Role of varicocele treatment in assisted reproductive technologies
ConclusionVaricocele repair is a cost-effective treatment method that can improve semen parameters, pregnancy rates, and live-birth rates in most infertile men with clinical varicocele. By improving semen parameters and sperm structure, varicocele repair can decrease or even eliminate ART requirement. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Arab J Urol
Publication date: March 2018Source: Arab Journal of Urology, Volume 16, Issue 1Author(s): Ashok Agarwal, Ahmad Majzoub, Mohamed Arafa, Haitham Elbardisi (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Geographical differences in semen characteristics of 13 892 infertile men
ConclusionSemen quality is generally lower in male infertility patients from the MENA region compared to non-MENA regions. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Lifestyle causes of male infertility
ConclusionThe major lifestyle factors discussed in the present review are amongst the multiple potential risk factors that could impair male fertility. However, their negative impact may well be mostly overcome by behaviour modification and better lifestyle choices. Greater awareness and recognition of the possible impact of these lifestyle factors are important amongst couples seeking conception. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Role of sperm DNA fragmentation in male factor infertility: A systematic review
ConclusionThe significant role of SDF in male factor infertility is supported by current evidence. The beneficial role of SDF testing in selection of varicocelectomy candidates, evaluation of patients with unexplained infertility and recurrent pregnancy loss, selection of the most appropriate assisted reproductive technique with highest success rate for infertile couples, and assessment of infertile men with modifiable lifestyle factors or gonadotoxin exposure has been recently proposed. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Role of reactive oxygen species in male infertility: An updated review of literature
ConclusionAlthough elevated levels of ROS are implicated as a cause of infertility, there is no consensus on selecting patients to test for ROS, which test to perform, or if treatment for ROS can have a positive impact on infertility rates and pregnancy. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Hyperprolactinaemia in male infertility: Clinical case scenarios
ConclusionHyperprolactinaemia, both directly and indirectly, has a negative effect on sperm production, and its detection and management in men seeking fertility is mandatory. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
A systematic review on the genetics of male infertility in the era of next-generation sequencing
ConclusionsMale infertility is a condition that is genetically heterogeneous, and therefore remarkably amenable to study by NGS. Although some headway has been made, given the high incidence of this condition despite its detrimental effect on reproductive fitness, there is significant potential for further discoveries. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
A systematic review on sperm DNA fragmentation in male factor infertility: Laboratory assessment
ConclusionThere are pros and cons to all the available SDF assays. TUNEL is a reliable technique with greater accuracy and as an additional diagnostic test in Andrology laboratories along with basic semen analysis can predict fertility outcome, and thus direct the choice of an assisted reproductive technology procedure for infertile couples. Also, the TUNEL assay can be used as a prognostic test and results are beneficial in deciding personalised treatment for infertile men. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Laboratory assessment of oxidative stress in semen
ConclusionTraditional OS laboratory assessments have their limitations. Amongst the prevalent laboratory techniques, ORP is novel and better option as it can be easily used in a clinical setting to provide a comprehensive review of OS. However, more studies are needed to evaluate its reproducibility across various laboratory centres. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
Laparoscopic renal surgery is here to stay
ConclusionWith the high cost and lack of overt clinical benefit of the robotic approach, laparoscopic renal surgery will likely continue to remain relevant in treating various urological pathologies. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - July 5, 2018 Category: Urology & Nephrology Source Type: research
