Systematic review of hormone replacement therapy in the infertile man
Conclusions Exogenous testosterone inhibits spermatogenesis. Hypogonadal men wanting to preserve their fertility and at the same time benefiting from TRT effects can be prescribed selective oestrogen receptor modulators or testosterone plus low-dose human chorionic gonadotrophin (hCG). Patients treated for infertility with hypogonadotrophic hypogonadism can be prescribed hCG alone at first followed by or in combination from the start with follicle-stimulating hormone preparations. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Preliminary study of prevalence for bladder cancer in Isfahan Province, Iran
Conclusion The PP for BC in the male population was 4.8-times higher than females. There was a 28.6% increase in the Ir over the study period. Further study concerning environmental exposure, genetic factors, job-related exposure to various chemical carcinogens, and geographical distribution in Isfahan and its’ rural provinces would seem to be valuable. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
A systematic review on sperm DNA fragmentation in male factor infertility: Laboratory assessment
Conclusion There are pros and cons to all the available SDF assays. TUNEL is a reliable technique with greater accuracy and as an additional diagnostic test in Andrology laboratories along with basic semen analysis can predict fertility outcome, and thus direct the choice of an assisted reproductive technology procedure for infertile couples. Also, the TUNEL assay can be used as a prognostic test and results are beneficial in deciding personalised treatment for infertile men. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Microscopic subinguinal varicocelectomy in 100 consecutive cases: Spermatic cord vascular anatomy, recurrence and hydrocele outcome analysis
Conclusion Microscopic subinguinal varicocelectomy accurately evaluated the detailed vascular anatomy of the spermatic cord, achieving excellent surgical outcome with minimal varicocele recurrence and hydrocele formation. Microscopic subinguinal varicocelectomy should be the ‘gold standard’ for varicocelectomy. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Oxidation –reduction potential and sperm DNA fragmentation, and their associations with sperm morphological anomalies amongst fertile and infertile men
Conclusion A direct inverse relationship exists between seminal ORP and SDF with various levels of normal sperm morphology. Using ORP and SDF measures in conjunction with standard semen morphology analysis could validate the result of the fertility status of patients. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Role of varicocele treatment in assisted reproductive technologies
Conclusion Varicocele repair is a cost-effective treatment method that can improve semen parameters, pregnancy rates, and live-birth rates in most infertile men with clinical varicocele. By improving semen parameters and sperm structure, varicocele repair can decrease or even eliminate ART requirement. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Geographical differences in semen characteristics of 13 892 infertile men
Conclusion Semen quality is generally lower in male infertility patients from the MENA region compared to non-MENA regions. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - February 10, 2018 Category: Urology & Nephrology Source Type: research
Systemic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate
Conclusion Antioxidants generally have a favourable effect on male fertility. Further studies are needed to identify the optimal antioxidant regimen that can be used safely and efficiently in clinical practice. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - January 3, 2018 Category: Urology & Nephrology Source Type: research
Systemic review of hormone replacement therapy in the infertile man
Conclusions Exogenous testosterone inhibits spermatogenesis. Hypogonadal men wanting to preserve their fertility and at the same time benefiting from TRT effects can be prescribed selective oestrogen receptor modulators or testosterone plus low-dose human chorionic gonadotrophin (hCG). Patients treated for infertility with hypogonadotrophic hypogonadism can be prescribed hCG alone at first followed by or in combination from the start with follicle-stimulating hormone preparations. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 31, 2017 Category: Urology & Nephrology Source Type: research
Update on the proteomics of male infertility: A systemic review
Conclusion In this molecular era, sperm proteomics has created a platform for enhanced understanding of male reproductive physiology as a potential tool for identification of novel protein biomarkers related to sperm function in infertile men. Therefore, it is believed that proteomic biomarkers can overcome the gaps in information from conventional semen analysis that are of limited clinical utility. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 29, 2017 Category: Urology & Nephrology Source Type: research
Spermatogonial stem cell transplantation and male infertility: Current status and future directions
Conclusions Evidence does not yet support clinical application of SSCs in humans. However, significant progress in the in vitro and in vivo development of SSCs, including differentiation into functional germ cells, gives reason for cautious optimism for future research. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 28, 2017 Category: Urology & Nephrology Source Type: research
Repair of panurethral stricture: Proximal ventral and distal dorsal onlay technique of buccal mucosal graft urethroplasty
Conclusions A proximal ventral and distal dorsal onlay technique of BMG urethroplasty is an available alternative for repairing panurethral stricture. The technique described is simple and easily reproducible with encouraging results compared to other similar techniques. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 27, 2017 Category: Urology & Nephrology Source Type: research
Advances in sperm retrieval techniques in azoospermic men: A systematic review
Conclusion Micro-TESE is the most efficient method for retrieving sperm but requires special expertise and can be traumatic for the testes. Conventional biopsies are twice more likely to retrieve sperm than fine-needle aspiration. Testicular aspiration performed by multiple passes into the testis is traumatic and is not efficient for sperm retrieval. Needle-aspiration biopsy and open real-time testicular mapping by the single seminiferous tubule technique can offer less traumatic methods for sperm retrieval, which can be tried before proceeding to micro-TESE. The first attempt at sperm retrieval is the best chance the pati...
Source: Arab Journal of Urology - December 26, 2017 Category: Urology & Nephrology Source Type: research
Comparing tamsulosin, silodosin versus silodosin plus tadalafil as medical expulsive therapy for lower ureteric stones: A randomised trial
Conclusion The present study concludes that the combination of silodosin and tadalafil increases the ureteric stone expulsion rate and decreases the expulsion time significantly. This combination provided significantly better control of pain without any serious side-effects. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 24, 2017 Category: Urology & Nephrology Source Type: research
Chromosomal abnormalities in infertile men with azoospermia and severe oligozoospermia in Qatar and their association with sperm retrieval intracytoplasmic sperm injection outcomes
Conclusion The incidence of chromosomal abnormalities in Qatar as a cause of severe male infertility is within a similar range as their prevalence internationally. (Source: Arab Journal of Urology)
Source: Arab Journal of Urology - December 23, 2017 Category: Urology & Nephrology Source Type: research
