Alzheimer's and Dementia: The Journal of the Alzheimer's Association This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Incidence of frontotemporal disorders in Olmsted County: A population-based study
DiscussionWe observed an increased incidence and trends of FTDs over time. This may reflect a better recognition by clinicians and improvement of clinical criteria and diagnostic tools. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 27, 2019 Category: Geriatrics Source Type: research

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration
We examined cognitive performance, behavioral ratings, and brain volumes from the first time point in 320 MAPT, GRN, and C9orf72 family members, including 102 non–mutation carriers, 103 asymptomatic carriers, 43 mildly/questionably symptomatic carriers, and 72 carriers with dementia.ResultsAsymptomatic carriers showed similar scores on all clinical measures compared with noncarriers but reduced frontal and temporal volumes. Those with mild/questionable impairment showed decreased verbal recall, fluency, and Trail Making Test performance and impaired mood and self-monitoring. Dementia was associated with impairment in all...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 27, 2019 Category: Geriatrics Source Type: research

Tau-positron emission tomography correlates with neuropathology findings
DiscussionElevated FTP-PET reflects Braak IV or greater neuropathology. Participants with primary age-related tauopathy and hippocampal sclerosis did not show elevated FTP-PET signal. Secondary neuropathologic diagnoses of Alzheimer's disease neuropathologic change can lead to borderline elevated FTP-PET signal. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 27, 2019 Category: Geriatrics Source Type: research

Clinical meaningfulness of subtle cognitive decline on longitudinal testing in preclinical AD
DiscussionEarly “subtle cognitive decline” among Aβ+ CN on a sensitive cognitive composite demonstrably increases risk for imminent clinical disease progression and functional impairment. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 21, 2019 Category: Geriatrics Source Type: research

A research framework for cognitive aging and Alzheimer's disease among diverse US Latinos: Design and implementation of the Hispanic Community Health Study/Study of Latinos—Investigation of Neurocognitive Aging (SOL-INCA)
Publication date: Available online 20 November 2019Source: Alzheimer's & DementiaAuthor(s): Hector M. González, Wassim Tarraf, Myriam Fornage, Kevin A. González, Albert Chai, Marston Youngblood, Maria de los Angeles Abreu, Donglin Zeng, Sonia Thomas, Gregory A. Talavera, Linda C. Gallo, Robert Kaplan, Martha L. Daviglus, Neil SchneidermanAbstractHispanics/Latinos are the largest ethnic/racial group in the United States and at high risk for Alzheimer's disease and related dementia (ADRD). Yet, ADRD among diverse Latinos is poorly understood and disparately understudied or unstudied compared to other ethnic/racial groups t...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 21, 2019 Category: Geriatrics Source Type: research

Apolipoprotein E genotype and the association between C-reactive protein and postoperative delirium: Importance of gene-protein interactions
DiscussionOur findings raise the possibility that APOE ε4 carrier status may modify the relationship between postoperative day 2 CRP levels and postoperative delirium. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 21, 2019 Category: Geriatrics Source Type: research

Corrigendum to “AMYPAD Diagnostic and Patient Management Study: Rationale and design” [Alzheimer's & Dementia 2019;15:388-99]
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Research Roundtable Considers Novel Treatment Approaches for Alzheimer's Disease
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): Stacie Weninger, Bjorn Sperling, Lisa J. Bain, Maria C. Carillo (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Contents
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Editorial Board
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Medical and Scientific Advisory Council
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Subscriber Information
Publication date: November 2019Source: Alzheimer's & Dementia, Volume 15, Issue 11Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Computerized cognitive performance assessments in the Brooklyn Cognitive Impairments in Health Disparities Pilot Study
DiscussionThe Cognigram was well liked in waiting rooms of primary care settings. Assistance from a trained adult and clinic endorsement were keys to success. How the Cognigram performs in a geographically compact, population-dense global setting, such as Brooklyn with high vascular disease risk and a plethora of health disparities, is being tested. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 19, 2019 Category: Geriatrics Source Type: research

Prevalence and correlates of mild cognitive impairment among diverse Hispanics/Latinos: Study of Latinos-Investigation of Neurocognitive Aging results
DiscussionMCI prevalence varied among Hispanic/Latino backgrounds, but not as widely as reported in the previous studies. CVD risk and depressive symptoms were associated with increased MCI, whereas APOE4 was not, suggesting alternative etiologies for MCI among diverse Hispanics/Latinos. Our findings suggest that mitigating CVD risk factors may offer important pathways to understanding and reducing MCI and possibly dementia among diverse Hispanics/Latinos. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 18, 2019 Category: Geriatrics Source Type: research

Leisure activity and social integration mitigate the risk of dementia related to cardiometabolic diseases: A population-based longitudinal study
DiscussionCMDs, especially when comorbid, are associated with increased dementia risk; however, leisure activities and social integration mitigate this risk. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - November 10, 2019 Category: Geriatrics Source Type: research