Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease
DiscussionBiologists can use these freely-available tools to obtain a comprehensive, information-rich view of the pathways in AD. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 30, 2019 Category: Geriatrics Source Type: research

Erratum to “Altered bile acid profile associates with cognitive impairment in Alzheimer’s disease—An emerging role for gut microbiome” [Alzheimer’s & Dementia 2019;15:76-92.]
Publication date: Available online 21 March 2019Source: Alzheimer's & DementiaAuthor(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 22, 2019 Category: Geriatrics Source Type: research

The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial
DiscussionComputerized cognitive training significantly improved global cognitive function, which was supported by the improved brain plasticity. Incorporation of biomarkers should be implemented in cognitive training trials. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 18, 2019 Category: Geriatrics Source Type: research

Impact of Helicobacter pylori and/or Helicobacter pylori–related metabolic syndrome on incidence of all-cause and Alzheimer's dementia
Publication date: Available online 11 March 2019Source: Alzheimer's & DementiaAuthor(s): Jannis Kountouras, Michael Doulberis, Stergios A. Polyzos, Taxiarchis Katsinelos, Elizabeth Vardaka, Constantinos Kountouras, Stergios Arapoglou, Aristomenis K. Exadaktylos, Georgia Deretzi, Magda Tsolaki, Marina Boziki, Panagiotis Katsinelos (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 12, 2019 Category: Geriatrics Source Type: research

A randomized clinical trial to evaluate home-based assessment of people over 75 years old
DiscussionRelatively low efficiency of internet-based assessment compared with testing by live-assessors has implications for internet-based recruitment and assessment efforts currently proposed for diverse populations. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 12, 2019 Category: Geriatrics Source Type: research

Primary age-related tauopathy (PART) and Alzheimer's disease (AD)
Publication date: Available online 8 March 2019Source: Alzheimer's & DementiaAuthor(s): Kurt A. Jellinger (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 9, 2019 Category: Geriatrics Source Type: research

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum
DiscussionAxonal degeneration, synaptic dysfunction, astroglial activation, and altered tau metabolism are involved already in preclinical AD. NFL may be a useful prognostic marker. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 9, 2019 Category: Geriatrics Source Type: research

Detecting both current and prior Helicobacter pylori infection is important to assess its impact on dementia
Publication date: Available online 8 March 2019Source: Alzheimer's & DementiaAuthor(s): Claire Roubaud-Baudron, Francis Mégraud, Nathalie Salles, Jean-François Dartigues, Luc Letenneur (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 9, 2019 Category: Geriatrics Source Type: research

The role of age on tau PET uptake and gray matter atrophy in atypical Alzheimer's disease
DiscussionAge is an important determinant of severity of cortical tau uptake in atypical AD, with young participants more likely to show widespread and severe cortical tau uptake. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 9, 2019 Category: Geriatrics Source Type: research

Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia
DiscussionSelf-reported TBI with loss of consciousness may not be an independent risk factor for clinical or pathological AD. Research that evaluates number and severity of TBIs is needed to clarify the neuropathological links between TBI and dementia documented in other large clinical databases. (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research

Contents
Publication date: March 2019Source: Alzheimer's & Dementia, Volume 15, Issue 3Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research

Editorial Board
Publication date: March 2019Source: Alzheimer's & Dementia, Volume 15, Issue 3Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research

Medical and Scientific Advisory Council
Publication date: March 2019Source: Alzheimer's & Dementia, Volume 15, Issue 3Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research

Subscriber Information
Publication date: March 2019Source: Alzheimer's & Dementia, Volume 15, Issue 3Author(s): (Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association)
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research

2019 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society. The Special Report examines the use of brief cognitive assessments by primary care physicians as a tool for improving early detection of dementia. An estimated 5.8 million Americans have Alzheimer's dementia. By mid-century, the number of people living with Alzheimer's dementia in the United States may grow to 13.8 million, fueled in large part by the aging baby boom generation. In 2017, official death certificates ...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - March 7, 2019 Category: Geriatrics Source Type: research