The thrill of the paper, the agony of the review
The process of first writing a scientific paper and then responding to reviewer comments can be challenging and sometimes—some might say often—frustrating. In this personal view, I recount some of my experiences as an author, and I offer some strategies to write a paper and to then respond to comments from the people who reviewed it. (Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - July 5, 2017 Category: Universities & Medical Training Authors: Curran-Everett, D. Tags: A PERSONAL VIEW Source Type: research

Effort and trust: the underpinnings of active learning
Three undergraduate students and their teacher discuss two crucial issues that form the implicit basis of active learning: effort and trust. They use a single course in a Health Sciences Program to anchor their comments. (Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - July 5, 2017 Category: Universities & Medical Training Authors: Adams, S., Bilimoria, K., Malhotra, N., Rangachari, P. K. Tags: A PERSONAL VIEW Source Type: research

A student guide to proofreading and writing in science
Scientific writing requires a distinct style and tone, whether the writing is intended for an undergraduate assignment or publication in a peer-reviewed journal. From the first to the final draft, scientific writing is an iterative process requiring practice, substantial feedback from peers and instructors, and comprehensive proofreading on the part of the writer. Teaching writing or proofreading is not common in university settings. Here, we present a collection of common undergraduate student writing mistakes and put forth suggestions for corrections as a first step toward proofreading and enhancing readability in subseq...
Source: AJP: Advances in Physiology Education - July 5, 2017 Category: Universities & Medical Training Authors: Hyatt, J.-P. K., Bienenstock, E. J., Tilan, J. U. Tags: A PERSONAL VIEW Source Type: research

Small steps to help improve the caliber of the reporting of statistics
(Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - July 5, 2017 Category: Universities & Medical Training Authors: Curran-Everett, D. Tags: EDITORIALS Source Type: research

Seeing is believing: a demonstration of critical fusion frequency and its multidimensional nature
(Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: Ganesh, G., Mahalingam, S., Annamalai, G., Damodharan, U. Tags: ILLUMINATIONS Source Type: research

Visualizing fundamental neuronal computation for life science students
(Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: Korngreen, A. Tags: ILLUMINATIONS Source Type: research

"Thinking ethics": a novel, pilot, proof-of-concept program of integrating ethics into the Physiology curriculum in South India
The objective of this exercise was to introduce an interactive and integrated ethics program into the Physiology course of first-year medical students and to evaluate their perceptions. Sixty medical students (30 men, 30 women) underwent 11 sessions over a 7-mo period. Two of the Physiology faculty conducted these sessions (20–30 min each) during the routine physiology (theory/practicals) classes that were of shorter duration and could, therefore, accommodate the discussion of related ethical issues. This exercise was in addition to the separate ethics classes conducted by the Medical Ethics department. The sessions ...
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: D, S., Vaz, M., Vaz, M. Tags: HOW WE TEACH Source Type: research

Measuring osmosis and hemolysis of red blood cells
Since the discovery of the composition and structure of the mammalian cell membrane, biologists have had a clearer understanding of how substances enter and exit the cell’s interior. The selectively permeable nature of the cell membrane allows the movement of some solutes and prevents the movement of others. This has important consequences for cell volume and the integrity of the cell and, as a result, is of utmost clinical importance, for example in the administration of isotonic intravenous infusions. The concepts of osmolarity and tonicity are often confused by students as impermeant isosmotic solutes such as NaCl...
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: Goodhead, L. K., MacMillan, F. M. Tags: HOW WE TEACH Source Type: research

A simple laboratory exercise with rat isolated esophagus and stomach fundus to reveal functional differences between striated and smooth muscle cells
This study describes an undergraduate student laboratory activity using isolated preparations from rat gastrointestinal tissues that possess contractile profiles typically exhibited by striated and smooth muscle cells. While students are introduced to an ex vivo methodology, they can compare differences in trace experiments, twitch aspects, phasic and tonic properties, force-frequency relationships, and pharmacological responsiveness of esophageal (striated) and fundic (smooth muscle) segments. Muscle strips were subjected to electrical field stimulation (EFS) applied by platinum electrodes immersed in the physiological so...
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: Batista-Lima, F. J., Gadelha, K. K. L., Oliveira, D. M., Vasconcelos, T. B., Brito, T. S., Magalhaes, P. J. C. Tags: HOW WE TEACH Source Type: research

Understanding the interrelationship between the synthesis of urea and gluconeogenesis by formulating an overall balanced equation
It is well known that a strong metabolic interrelationship exists between ureagenesis and gluconeogenesis. In this paper, we present a detailed, overall equation, describing a possible metabolic link between ureagenesis and gluconeogenesis. We adopted a guided approach in which we strongly suggest that students, when faced with the problem of obtaining the overall equation of a metabolic pathway, carefully account for all atoms and charges of the single reactions, as well as the cellular localizations of the substrates, and the related transport systems. If this suggestion is always taken into account, a balanced, overall ...
Source: AJP: Advances in Physiology Education - May 19, 2017 Category: Universities & Medical Training Authors: Ipata, P. L., Pesi, R. Tags: STAYING CURRENT Source Type: research

Avoiding the chopping block in curricular reform: reimagining physiology laboratories in the era of integrated medical curricula
(Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - April 25, 2017 Category: Universities & Medical Training Authors: Flagg, T. P., Rothwell, S., Neubauer, B. Tags: ILLUMINATIONS Source Type: research

Structure-function relations in physiology education: Wheres the mechanism?
Physiology demands systems thinking: reasoning within and between levels of biological organization and across different organ systems. Many physiological mechanisms explain how structures and their properties interact at one level of organization to produce emergent functions at a higher level of organization. Current physiology principles, such as structure-function relations, selectively neglect mechanisms by not mentioning this term explicitly. We explored how students characterized mechanisms and functions to shed light on how students make sense of these terms. Students characterized mechanisms as 1) processes that o...
Source: AJP: Advances in Physiology Education - April 25, 2017 Category: Universities & Medical Training Authors: Lira, M. E., Gardner, S. M. Tags: HOW WE TEACH Source Type: research

Novel use of a noninvasive hemodynamic monitor in a personalized, active learning simulation
The present study furthered the concept of simulation-based medical education by applying a personalized active learning component. We tested this novel approach utilizing a noninvasive hemodynamic monitor with the capability to measure and display in real time numerous hemodynamic parameters in the exercising participant. Changes in medical knowledge concerning physiology were examined with a pre-and posttest. Simply by observation of one's own hemodynamic variables, the understanding of complex physiological concepts was significantly enhanced. (Source: AJP: Advances in Physiology Education)
Source: AJP: Advances in Physiology Education - April 25, 2017 Category: Universities & Medical Training Authors: Zoller, J. K., He, J., Ballew, A. T., Orr, W. N., Flynn, B. C. Tags: HOW WE TEACH Source Type: research

Validating a conceptual framework for the core concept of "cell-cell communication"
We have created and validated a conceptual framework for the core physiology concept of "cell-cell communication." The conceptual framework is composed of 51 items arranged in a hierarchy that is, in some instances, four levels deep. We have validated it with input from faculty who teach at a wide variety of institutional types. All items making up the framework were deemed essential to moderately important. However, some of the main ideas were clearly judged to be more important than others. Furthermore, the lower in the hierarchy an item is, the less important it is thought to be. Finally, there was no significant differ...
Source: AJP: Advances in Physiology Education - April 25, 2017 Category: Universities & Medical Training Authors: Michael, J., Martinkova, P., McFarland, J., Wright, A., Cliff, W., Modell, H., Wenderoth, M. P. Tags: HOW WE TEACH Source Type: research

Nobel Laureate A. V. Hill and the refugee scholars, 1933-1945
A. V. Hill shared the 1922 Nobel Prize in Physiology or Medicine for his investigation of the energetics of muscular contraction. His scientific work has been well chronicled over many years (Rall JA. Mechanism of Muscular Contraction, 2014). There is the natural tendency to focus solely on an investigator’s scientific achievements. But in the case of Hill, it has been said (Katz B. Biogr Mem Fellows R Soc 24: 71–149, 1978) that "it was his devotion to such wider issues, outside the boundaries of his own research, through which he exerted his most important influence on other people’s lives and on the cou...
Source: AJP: Advances in Physiology Education - April 25, 2017 Category: Universities & Medical Training Authors: Rall, J. A. Tags: HISTORICAL PERSPECTIVES Source Type: research