Blood Pressure during Blood Collection and the Implication for Absolute Cardiovascular Risk Assessment
Conclusion: Absolute CVD risk calculation is not affected by use of SBP measurements recorded at the time of blood collection. Therefore, it is acceptable to collect blood and measure BP during the same consultation for absolute CVD risk assessment.Pulse (Source: Pulse)
Source: Pulse - June 2, 2020 Category: Cardiology Source Type: research

Resting Left Ventricular Dyssynchrony and Mechanical Reserve in Asymptomatic Normotensive Subjects with Early Type 2 Diabetes Mellitus
Conclusion: The LVdys (Ts-SD-12) cutoff ≥36.5 ms was the optimal value for prediction of impaired LVMR and might be an early marker of subclinical cardiac dysfunction and risk stratification of subjects with asymptomatic early T2DM with preserved left ventricular ejection fraction.Pulse (Source: Pulse)
Source: Pulse - June 2, 2020 Category: Cardiology Source Type: research

Insight into Atrial Fibrillation in LVAD Patients: From Clinical Implications to Prognosis
The use of left ventricular assist devices (LVADs), whether for destination therapy or bridge to transplantation, has gained increasing validation in recent years in patients with advanced heart failure. Arrhythmias can be the most challenging variables in the management of such patients but the main attention has always been focused on ventricular arrhythmias given the detrimental impact on mortality. Nevertheless, atrial fibrillation (AF) is the most common rhythm disorder associated with advanced heart failure and may therefore characterize the LVADs ’ pre- and postimplantation periods. Indeed, the consequences of AF ...
Source: Pulse - April 28, 2020 Category: Cardiology Source Type: research

Contents Vol. 7, 2019
Pulse 2019;7:I –II (Source: Pulse)
Source: Pulse - March 25, 2020 Category: Cardiology Source Type: research

Clinical Classification of Arrhythmogenic Right Ventricular Cardiomyopathy
Conclusions: The described clinical forms of ARVC are determined by a combination of genetic and environmental factors and do not transform into each other. The proposed classification could be used in clinical practice to determine the range of diagnostic and therapeutic measures and to assess the prognosis of the disease in a particular patient.Pulse (Source: Pulse)
Source: Pulse - February 11, 2020 Category: Cardiology Source Type: research

The Role of Heart Rate Variability and Fragmented QRS for Determination of Subclinical Cardiac Involvement in Beta-Thalassemia Major
Conclusions: We observed a higher prevalence of low limb voltage and low atrial rhythm in TM cases versus non-TM cases. Indeed, the role of fragmented QRS (fQRS) for subclinical detection of cardiac disease in TM cases is still so controversial and needs more evaluation. Application of HRV and fQRS in this regard may need to be performed at the right time point after initiation of blood transfusion, but this needs to be determined.Pulse (Source: Pulse)
Source: Pulse - February 11, 2020 Category: Cardiology Source Type: research

Aortic Pulse Wave Velocity, Ankle-Brachial Index, and Malondialdehyde in Older Adults with or without Metabolic Syndrome
Metabolic syndrome is an important health problem associated with both subclinical atherosclerosis and an increased risk of cardiovascular disease and it leads to an elevated total mortality. Aortic pulse wave velocity (aPWV) is widely used for noninvasive assessment of arterial stiffness. Ankle-brachial index (ABI) predicts peripheral arterial disease (PAD) of the lower extremities. In addition, malondialdehyde (MDA) is thought to be involved in the development of arterial stiffness. The present study aimed to: (1) compare aPWV, ABI, and MDA between participants with MetS and those without MetS and (2) investigate the cor...
Source: Pulse - February 11, 2020 Category: Cardiology Source Type: research

Vascular Structure and Inflammation in a South African Population: The SABPA Study
Conclusion: The early structural changes observed are not related to higher inflammatory levels in this South African population. Future studies are needed to investigate the possible protective effect of suPAR on early changes in vascular structure, especially with the focus on cardiovascular disease prevention.Pulse 2019;7:60 –68 (Source: Pulse)
Source: Pulse - July 10, 2019 Category: Cardiology Source Type: research

The Pulse of Asia 2019 Shanghai
Pulse (Source: Pulse)
Source: Pulse - April 15, 2019 Category: Cardiology Source Type: research

Contents Vol. 6
Pulse 2018;6:I –IV (Source: Pulse)
Source: Pulse - April 15, 2019 Category: Cardiology Source Type: research

The Effect of Head-Out Aquatic Exercise on Arterial Stiffness in Middle-Aged and Elderly People
Aquatic exercise is ideal for older adults because it mitigates weight-bearing stress. However, the effect of head-out aquatic exercise on arterial stiffness, a strong future cardiovascular disease (CVD) risk, remains unclear. We determined whether head-out aquatic exercise would mitigate arterial stiffness in middle-aged and elderly people. In 25 middle-aged and older people (9 men, mean age 64 ± 8 years), blood pressure (BP) and brachial-ankle pulse wave velocity (baPWV) were measured before and after a supervised aquatic exercise training program (60 min, 1 session/week, 14 sessions) which mainly consisted of walking, ...
Source: Pulse - April 15, 2019 Category: Cardiology Source Type: research

Genome-Wide Association Studies of Hypertension and Several Other Cardiovascular Diseases
Genome-wide association studies (GWAS) have greatly expanded our understanding of the genetic architecture of cardiovascular diseases in the past decade. They have revealed hundreds of suggestive genetic loci that replicate known biological candidate genes and indicate the existence of a previously unsuspected new biology relevant to cardiovascular disorders. These data have been used successfully to create genetic risk scores that may improve risk prediction and the identification of susceptive individuals. Furthermore, these GWAS-identified novel pathways may herald a new era of novel drug development and stratification ...
Source: Pulse - February 5, 2019 Category: Cardiology Source Type: research

Cuff-Based Oscillometric Measurements of Central Hemodynamics: Factors Influencing Central Augmentation Pressure in Normotensive Japanese Individuals
Conclusions: Age, sex, and height influenced central AP, as assessed using the Mobil-O-Graph. Age-related increase in central AP was observed in normotensive Japanese individuals. Brachial cuff-based waveform recordings using the Mobil-O-Graph are feasible for the estimation of central AP in the Asian population.Pulse 2018;6:161 –168 (Source: Pulse)
Source: Pulse - January 31, 2019 Category: Cardiology Source Type: research

Association of Hemoglobin and Blood Pressure in a Chinese Community-Dwelling Population
This study investigated the relationship between hemoglobin (Hb) level and blood pressure in a Chinese community-dwelling population with normal glucose metabolism. Hb, fasting plasma glucose, glycated Hb A1c, hepatic and renal function, lipid, electrolytes, and anthropometric parameters were measured. Hb level was found to be positively correlated with systolic (SBP;r = 0.075,p #x3c; 0.001) and diastolic (DBP;r = 0.272,p #x3c; 0.001) blood pressure in the cohort. The relationship was not affected by age, BMI, serum creatinine (Cr), and low-density lipoprotein (LDL) in both males and females. Multivariate stepwise regressi...
Source: Pulse - November 28, 2018 Category: Cardiology Source Type: research

Urinary Metabolites and Their Link with Premature Arterial Stiffness in Black Boys: The ASOS Study
Conclusion: Our study is the first to discover the associations of pulse wave velocity with β-alanine, 1-methylhistidine, and L-proline in children from South Africa, which may suggest potential early compromise in cardiac protective metabolic pathways in black boys as young as 6 years of age.Pulse 2018;6:144 –153 (Source: Pulse)
Source: Pulse - August 17, 2018 Category: Cardiology Source Type: research