Asian Guidelines on Hypertension
Pulse 2015;3:12-13 (Source: Pulse)
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Hypertension Guidelines: Timely New Initiatives from East Asia
Pulse 2015;3:1-3 (Source: Pulse)
Source: Pulse - April 28, 2015 Category: Cardiology Source Type: research

Lifestyle Factors and Coronary Artery Calcification
This article briefly reviews whether lifestyle factors relate to subclinical atherosclerosis as assessed by coronary artery calcification in asymptomatic individuals.Pulse 2014;2:95-102 (Source: Pulse)
Source: Pulse - March 11, 2015 Category: Cardiology Source Type: research

Clinical Considerations for the Association between Vascular Damage and Chronic Kidney Disease
Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease. Recently, noninvasive and simple morphological and functional methods have been introduced to assess atherosclerotic vascular damage. This review describes the association of CKD with vascular damage as assessed by these methods. Carotid intima-media thickness (IMT) and coronary artery calcium score (CACS) are morphological parameters of vascular damage, and an ankle-brachial index (ABI) (Source: Pulse)
Source: Pulse - February 26, 2015 Category: Cardiology Source Type: research

Arterial Stiffness in Children: Pediatric Measurement and Considerations
Conclusions: The measurement of arterial stiffness in children is feasible and, under controlled conditions, can give accurate information about the underlying state of the arteries. This potentially adds valuable information about the functionality of the cardiovascular system in children with a variety of chronic diseases well beyond that of the brachial artery blood pressure.Pulse 2014;2:69-80 (Source: Pulse)
Source: Pulse - February 17, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: Is the Future Now
Pulse 2014;2:63-68 (Source: Pulse)
Source: Pulse - February 3, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: A Window into the Future
The aorta has limited ability to accommodate increasing body size by remodeling. The dramatic rise in pediatric obesity threatens to overwhelm this intrinsic remodeling program and lead to abnormal aortic function. As hypothesized, pulse pressure, as an index of aortic function, has indeed risen dramatically in parallel with the rise of pediatric obesity, while at the same time mean arterial pressure, as an index of small resistance artery function, has fallen. These divergent large-artery-versus-small-artery indices may combine to explain the counterintuitive decrease in systolic blood pressure in children and adults duri...
Source: Pulse - February 3, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: Is the Future Now?
Pulse 2014;2:63-68 (Source: Pulse)
Source: Pulse - February 2, 2015 Category: Cardiology Source Type: research

Pulsatile and Steady-State Pressure Trends in Children: A Window into the Future?
The aorta has limited ability to accommodate increasing body size by remodeling. The dramatic rise in pediatric obesity threatens to overwhelm this intrinsic remodeling program and lead to abnormal aortic function. As hypothesized, pulse pressure, as an index of aortic function, has indeed risen dramatically in parallel with the rise of pediatric obesity, while at the same time mean arterial pressure, as an index of small resistance artery function, has fallen. These divergent large-artery-versus-small-artery indices may combine to explain the counterintuitive decrease in systolic blood pressure in children and adults duri...
Source: Pulse - February 2, 2015 Category: Cardiology Source Type: research

Noninvasive and Invasive Assessments of the Functional Significance of Intermediate Coronary Artery Stenosis: Is This a Matter of Right or Wrong?
Coronary computed tomographic angiography (cCTA) has emerged in recent years as a noninvasive modality to evaluate coronary artery disease. Many studies have revealed the excellent diagnostic accuracy of cCTA when compared with invasive coronary angiography (ICA) or intravascular ultrasound (IVUS). It is generally accepted that the functional significance of coronary artery stenosis is important to make treatment decisions; however, cCTA, ICA, and IVUS are limited in the ability to determine the physiologic significance of coronary stenosis. The FIGURE-OUT study compared the noninvasive and invasive assessment of the funct...
Source: Pulse - December 16, 2014 Category: Cardiology Source Type: research

Risk Associated with Pulse Pressure on Out-of-Office Blood Pressure Measurement
Background: Longitudinal studies have demonstrated that the risk of cardiovascular disease increases with pulse pressure (PP). However, PP remains an elusive cardiovascular risk factor with findings being inconsistent between studies. The 2013 ESH/ESC guideline proposed that PP is useful in stratification and suggested a threshold of 60 mm Hg, which is 10 mm Hg higher compared to that in the 2007 guideline; however, no justification for this increase was provided. Methodology: Published thresholds of PP are based on office blood pressure measurement and often on arbitrary categorical analyses. In the International Database...
Source: Pulse - November 20, 2014 Category: Cardiology Source Type: research

Hypertensive Vasculopathy
An exclusive interview by Prof. Jeong Bae Park conducted with Dr. Rhian M. Touyz in Seoul while she was visiting for the Korean Society of Hypertension, May 10, 2014. In this interview, Dr. Touyz explains and describes hypertensive vasculopathy.Pulse 2014;2:38-41 (Source: Pulse)
Source: Pulse - November 13, 2014 Category: Cardiology Source Type: research

Pulse Pressure Is Useful for Determining the Choice of Antihypertensive Drugs in Postmenopausal Women
Objective: To assess the efficacy of various classes of antihypertensive drugs in postmenopausal women with hypertension using pulse pressure (PP) as an index. Patients and Methods: Selected women were required to be naturally menopausal for at least 1 year but not more than 5 years past their menstrual period. Exclusion criteria were a history of preeclampsia or eclampsia, a severe illness such as myocardial infarction or stroke within 6 months, the use of estrogens or progestins within 3 months, proteinuric nephropathy, and surgically induced menopause. There were 114 women who participated in this study after having giv...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Exercise Hypertension
Irrespective of apparent ‘normal' resting blood pressure (BP), some individuals may experience an excessive elevation in BP with exercise (i.e. systolic BP ≥210 mm Hg in men or ≥190 mm Hg in women or diastolic BP ≥110 mm Hg in men or women), a condition termed exercise hypertension or a ‘hypertensive response to exercise' (HRE). An HRE is a relatively common condition that is identified during standard exercise stress testing; however, due to a lack of information with respect to the clinical ramifications of an HRE, little value is usually placed on such a finding. In this review, we discuss both the clinical im...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

The Efficacy of Fimasartan for Cardiovascular Events and Metabolic Syndrome (K-MetS Study): Rationale, Design and Participant Characteristics
Fimasartan, the eighth angiotensin receptor blocker, was launched in March 2011 and was found to have an excellent efficacy and safety profile in a large cross-sectional population study [Safety and Efficacy of Fimasartan in Patients with Arterial Hypertension (Safe-KanArb); Park et al.: Am J Cardiovasc Drugs 2013;13:47-56]. However, there is no long-term study to evaluate its efficacy for major adverse cardiovascular events (MACE) and other effects. The purpose of this study (K-MetS study) was to evaluate whether the early reduction of blood pressure (BP) and/or correction of metabolic derangements with fimasartan will af...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research