New Predictor of Cancer (Robert H. Lurie Comprehensive Cancer Center of Northwestern University)
Epigenetic age is a new way to measure your biological age. When your biological (epigenetic) age is older than your chronological age, you are at increased risk for getting and dying of cancer, reports a new Northwestern Medicine study. Robert H. Lurie Comprehensive Cancer Center of Northwestern University is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 17, 2016 Category: Cancer & Oncology Source Type: news

Some Chemotherapy Drugs May Increase the Percentage of Patients whose Tumors Respond to Immune Checkpoint Therapy (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)
The use of certain traditional chemotherapy drugs may expand the number of tumors that respond to one of today's most promising cancer therapies - immune checkpoint blockade. Researchers from the Massachusetts General Hospital Center for Systems Biology report in the Feb. 16 issue of the journal Immunity that inducing the infiltration of cytotoxic T cells (CTLs) - immune cells that kill cancer cells and cells that are infected or in other ways damaged - into lung tumors sensitized otherwise unre... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 16, 2016 Category: Cancer & Oncology Source Type: news

MD Anderson Researchers Propose New Staging for HPV-Related Oropharyngeal Cancer (The University of Texas MD Anderson Cancer Center)
Human papillomavirus (HPV) status is a strong predictor of prognosis for patients with oropharyngeal carcinoma (OPC), but the current staging system does not adequately account for biological and clinical differences between HPV-positive OPC and HPV-negative OPC, commonly caused by alcohol and tobacco use. With rates of HPV-related OPC rising rapidly, researchers at The University of Texas MD Anderson Cancer Center propose a new staging system to more accurately predict patient outcomes and iden... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 16, 2016 Category: Cancer & Oncology Source Type: news

Discovery Lays the Foundation to Expand Personalized Chemotherapy for Leukemia Patients (St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center)
An international research team has determined how inherited gene variations lead to severe drug toxicity that may threaten chances for a cure in children with leukemia. St. Jude Children's Research Hospital scientists led the study, results of which set the stage to expand the use of a patient's genetic make-up to tailor chemotherapy. St. Jude Children's Research Center/The University of Tennessee Health Science Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 15, 2016 Category: Cancer & Oncology Source Type: news

New NCCN Guidelines Include Evidence Blocks to Illustrate Value in Breast, Colon, Kidney, and Rectal Cancers
NCCN Guidelines with NCCN Evidence Blocks™ for Breast, Colon, Kidney, and Rectal Cancers illustrate five dimensions of value for therapeutic regimens: efficacy, safety, quality and quantity of evidence, consistency of evidence, and affordability. FORT WASHINGTON, PA -The National Comprehensive Cancer Network® (NCCN®) has published the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) with NCCN Evidence Blocks™ for Breast, Colon, Kidney, and Rectal Cancers. Part of NCCN's n... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 14, 2016 Category: Cancer & Oncology Source Type: news

Study Finds Mechanism by which Obesity Promotes Pancreatic and Breast Cancer (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)
Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of obesity to promote cancer progression. In their report published online in the journal Clinical Cancer Research, the research team describes finding an association between obesity and an overabundance of a factor called PlGF (placental growth factor) and that PlGF's binding to its receptor VEGFR-1, which is expressed on immune cells within tumors, promotes tumor progression. Their findings in... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 12, 2016 Category: Cancer & Oncology Source Type: news

NCCN Awarded $2 Million in Research Funding from Infinity Pharmaceuticals to Study Duvelisib in Hematologic Malignancies
The NCCN Oncology Research Program (ORP) was awarded a $2-million grant from Infinity Pharmaceuticals, Inc. to facilitate studies of duvelisib in the treatment of hematologic malignancies. FORT WASHINGTON, PA - The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has been awarded a $2-million grant from Infinity Pharmaceuticals, Inc. to evaluate the safety and effectiveness of duvelisib as a potential treatment for hematologic malignancies. 'NCCN ORP is plea... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 12, 2016 Category: Cancer & Oncology Source Type: news

NCCN Supports the Global Fight against Cancer on World Cancer Day 2016
The National Comprehensive Cancer Network® (NCCN®) is proud to support World Cancer Day 2016 and take action to reduce the impact that cancer has on individuals, families, and communities. With more than 14 million people affected by cancer each year, it is our mission, an alliance of 26 of the leading cancer centers, to improve the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. Each year, NCCN's esteemed experts volunteer more than 26... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 6, 2016 Category: Cancer & Oncology Source Type: news

Prostate Cancer Survivors ’ Risk of Heart Disease Studied (Vanderbilt-Ingram Cancer Center)
The 3 million prostate cancer survivors in the United States are likely to die from something other than cancer, thanks to early detection, effective treatment, and the disease's slow progression. What survivors need to be more concerned with is heart disease, the most common non-cancer cause of death for men with prostate cancer, according to a paper published this week in Circulation, authored by Vanderbilt physicians. Vanderbilt-Ingram Cancer Center is one of the 26 NCCN Member Institut ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 4, 2016 Category: Cancer & Oncology Source Type: news

Renowned Oncologist Dr. Marc Ernstoff to Assume Leadership Roles at UB, Roswell Park (Roswell Park Cancer Institute)
Marc S. Ernstoff, MD, has been appointed professor and chief of the Division of Hematology/Oncology in the Department of Medicine in the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo (UB), and chair of the Department of Medicine and senior vice president of clinical investigation at Roswell Park Cancer Institute (RPCI). Ernstoff also will serve as chief of the Division of Hematology/Oncology at UBMD Internal Medicine, the clinical practice plan of the UB Departme... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 4, 2016 Category: Cancer & Oncology Source Type: news

Prostate Cancer Survivors’ Risk of Heart Disease Studied (Vanderbilt-Ingram Cancer Center)
The 3 million prostate cancer survivors in the United States are likely to die from something other than cancer, thanks to early detection, effective treatment, and the disease's slow progression. What survivors need to be more concerned with is heart disease, the most common non-cancer cause of death for men with prostate cancer, according to a paper published this week in Circulation, authored by Vanderbilt physicians. Vanderbilt-Ingram Cancer Center is one of the 26 NCCN Member Institut... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 4, 2016 Category: Cancer & Oncology Source Type: news

Meditation Eases Pain, Anxiety and Fatigue during Breast Cancer Biopsy (Duke Cancer Institute)
Meditation eases anxiety, fatigue and pain for women undergoing breast cancer biopsies, according to researchers at the Duke Cancer Institute. They also found that music is effective, but to a lesser extent. Duke Cancer Institute is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 4, 2016 Category: Cancer & Oncology Source Type: news

Investigating Surgery for Women at High Risk of Breast and Ovarian Cancer (Mayo Clinic Cancer Center)
In a review article published in the Feb. 4 issue of the New England Journal of Medicine, a pair of Mayo Clinic Cancer Center researchers provide an in-depth look at the issues associated with the care of women in families with hereditary breast and ovarian cancer syndrome who have not yet developed cancer themselves. The article addresses optimal risk assessment for breast and ovarian cancers, the usefulness of risk-reducing surgery, side effects of these procedures, alternative strategies for ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 3, 2016 Category: Cancer & Oncology Source Type: news

Does Radiation Therapy Improve Survival for Women with Ductal Carcinoma in Situ (DCIS)? Yes...and...No. (Dana-Farber/Brigham and Women’s Cancer Center)
Approximately 60,000 patients in the United States will receive a diagnosis of ductal carcinoma in situ (DCIS) in 2016. DCIS is not an invasive form of cancer and the 10-year survival rate for women with DCIS is greater than 98 percent. However, incidence of DCIS has increased dramatically over the last three decades, and being able to determine which women are among the small percentage at higher risk of breast cancer recurrence and mortality could help clinicians and patients tailor treatment ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 1, 2016 Category: Cancer & Oncology Source Type: news

Shedding New Light on Breast Cancer Metastases (Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance)
A new study by researchers at Fred Hutchinson Cancer Research Center and Johns Hopkins Medical Institute, published in PNAS Early Edition, confirmed that clusters of cancer cells indeed travel together throughout all stages of metastasis. The study also identified the molecular signatures unique to these highly aggressive, roaming tumor clumps, such as the fact that each are led by a gang member that's fueled by a type of cellular kryptonite: a highly expressed protein called keratin 14. Fred... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - February 1, 2016 Category: Cancer & Oncology Source Type: news