Fertility after Cancer: Young Woman Less Likely to be Told about Options
A new nationwide study by researchers at Fred Hutchinson Cancer Research Center and Seattle Children's reveals that young male patients were twice as likely as young women to be counseled on ways to preserve their fertility, such as freezing sperm or eggs. Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 27, 2015 Category: Cancer & Oncology Source Type: news

Gene Therapy May Improve Survival of Patients with Recurrent Ovarian Cancer
Use of gene therapy to deliver a protein that suppresses the development of female reproductive organs may improve the survival of patients with ovarian cancer that has recurred after chemotherapy, which happens 70 percent of the time and is invariably fatal. In their report, a Massachusetts General Hospital research team describes how a single injection of a modified version of Mullerian Inhibiting Substance, a protein critical to sexual development, carried on a commonly used viral vector sup... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 27, 2015 Category: Cancer & Oncology Source Type: news

New Drug for Blood Cancers Now in Five Phase II Clinical Trials
Researchers at University of California, San Diego School of Medicine have established the safety and dosing of a new drug for treating blood cancers. The findings are published online July 27 in The Lancet Haematology. The drug is a small molecule inhibitor that suppresses the activity of a signaling pathway believed to contribute to a variety of blood cancers' eventual resistance to standard chemotherapy treatments. UC San Diego Moores Cancer Center is one of the 26 NCCN Member Instituti... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 27, 2015 Category: Cancer & Oncology Source Type: news

Doctors Speak Out Against 'Unsustainable' Rise In Cancer Drug Prices
According to 118 leading oncologists, there's some good news about cancer drugs. New ones are being developed faster than ever. Here's the bad news. A lot of cancer patients can't afford them. In a commentary published Thursday by the journal of the Mayo Clinic Clinic Cancer Center, the oncologists call the steady rise in the price of cancer drugs unsustainable. Mayo Clinic Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 25, 2015 Category: Cancer & Oncology Source Type: news

Lymph Node Radiation May Halt Breast Cancer Recurrences
Two new studies show promising results for the use of radiation therapy to prevent breast cancer from coming back. The research shows that when patients with breast cancer received radiation therapy to their lymph nodes - not just the area of the breast where cancer occurred - cancer did not recur in the original site or spread to other parts of the body. Interestingly, the results were the same regardless of whether the cancer had spread to the lymph nodes. Case Comprehensive Cancer Cente... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 23, 2015 Category: Cancer & Oncology Source Type: news

For Prostate Cancer Patients, Risk-Specific Therapies Now More the Norm
After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UCSF Helen Diller Family Comprehensive Cancer Center-one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 23, 2015 Category: Cancer & Oncology Source Type: news

Study Explores Protein’s Role in Inflammation-Associated Cancer
A protein that transports the micronutrient selenium and has antioxidant functions may protect against colitis-associated carcinoma - colon cancer that develops in patients with inflammatory bowel disease, according to a new Vanderbilt-Ingram Cancer Center-led study. The findings, reported in the July 2015 issue of the Journal of Clinical Investigation, could suggest strategies for reducing colon cancer risk in these patients. Vanderbilt-Ingram Cancer Center is one of the 26 NCCN Member In... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 23, 2015 Category: Cancer & Oncology Source Type: news

Researchers Decode Molecular Action of Combination Therapy for a Deadly Thyroid Cancer
In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic Cancer Center's Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal. In testing multiple HDAC inhibitors in combination with the chemotherapy drug paclitaxel, known to give some benefit for this aggressive cancer, they found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemoth... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 23, 2015 Category: Cancer & Oncology Source Type: news

Finding Better Ways to Fight Cancer Means Starting with the Basics (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)
Having a team of scientists working on basic science at a cancer institute may seem unusual, but Kai W. Wucherpfennig, MD, PhD, co-chair of the Department of Cancer Immunology and Virology at Dana-Farber Cancer Institute, says it makes perfect sense. Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospital Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 23, 2015 Category: Cancer & Oncology Source Type: news

Moffitt Cancer Center Researchers Develop First Genetic Test to Predict Tumor Sensitivity to Radiation Therapy
Recent advances in the understanding of cancer have led to more personalized therapies, such as drugs that target particular proteins and tests that analyze gene expression patterns in tumors to predict a patient's response to therapy. Moffitt Cancer Center researchers have contributed to these advances by developing the first test that analyzes the sensitivity of tumors to radiation therapy. They discovered that colon cancer metastases have varying sensitivity to radiation therapy based on thei... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 22, 2015 Category: Cancer & Oncology Source Type: news

Poor Survival in Multiple Myeloma Patients Linked to Genetic Variation
As part of a multi-institutional effort, researchers with Huntsman Cancer Institute at the University of Utah have found that multiple myeloma patients with a genetic variation in the gene FOPNL die on average one to three years sooner than patients without it. The finding was identified with a genetic mapping technique, genome wide association studies (GWAS), and verified in patient populations from North America and Europe. This was the first study to survey the entire human genome for genetic... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 22, 2015 Category: Cancer & Oncology Source Type: news

Salmonella Bacterium Could Prove Potent Foe to Aggressive Form of Pancreatic Cancer (City of Hope Comprehensive Cancer Center)
Patients with an aggressive form of pancreatic cancer known as pancreatic ductal adenocarcinoma currently have few good therapeutic options, with most medications able to increase survival by only a few months while exacting a high physical toll. City of Hope researchers appear to have found a better option, one that uses the Salmonella bacterium. City of Hope Comprehensive Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - July 1, 2015 Category: Cancer & Oncology Source Type: news

Mayo Clinic Study Suggests which Glioblastoma Patients May Benefit from Drug Treatment (Mayo Clinic Cancer Center)
Clinicians testing the drug dasatinib, approved for several blood cancers, had hoped it would slow the aggressive growth of the deadly brain cancer glioblastoma; however, clinical trials to date have not found any benefit. Researchers at Mayo Clinic, who conducted one of those clinical trials, believe they know why dasatinib failed - and what to do about it. Mayo Clinic Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - June 30, 2015 Category: Cancer & Oncology Source Type: news

10 Years to Cancer Cures 'Actually Plausible,' Fred Hutch President Says (Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance)
The future of cancer therapy looks 'incredibly promising,' Dr. D. Gary Gilliland, president and director of Fred Hutchinson Cancer Research Center, said Tuesday. 'It's actually plausible that in 10 years we'll have curative therapies for most if not all human cancers,' Gilliland told hundreds of industry and research leaders from around the world who were gathered in Seattle at the 2015 Life Science Innovation Northwest conference, an event hosted by the Washington Biotechnology & Biomed... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - June 30, 2015 Category: Cancer & Oncology Source Type: news

Protein’s Impact on Colorectal Cancer is Dappled (UC San Diego Moores Cancer Center)
Researchers at University of California, San Diego School of Medicine have discovered a cell signaling pathway that appears to exert some control over initiation and progression of colorectal cancer, the third leading cause of cancer-related death in the United States. A key protein in the pathway also appears to be predictive of cancer survival rates. UC San Diego Moores Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - June 30, 2015 Category: Cancer & Oncology Source Type: news