UCSF Research Suggests New Model for Cancer Metastasis (UCSF Helen Diller Family Comprehensive Cancer Center)
Scientists at UC San Francisco have been able to directly observe, for the first time, how invasive cancer cells create a beachhead as they migrate to the lung in a mouse model of metastatic cancer. What they saw was utterly surprising: early 'pioneer' cancer cells that lodge in the lung generally die, but first they shed zombie-like particles that move around on their own and get gobbled up by waves of immune cells. Many of these immune cells, as if infected by the cancer particles, then burrow... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 16, 2016 Category: Cancer & Oncology Source Type: news

New Lung Cancer Therapy May Target Previously Untreatable Tumors (Memorial Sloan Kettering Cancer Center)
Although some lung cancer patients have benefited from developments in precision therapy, those with mutations in a gene called KRAS have not. Now Memorial Sloan Kettering Cancer Center researchers are developing uses for a compound that targets a common KRAS mutation in lung cancer. Memorial Sloan Kettering Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 15, 2016 Category: Cancer & Oncology Source Type: news

Higher Volume Radiation Facilities Associated with Better Survival Rates for Men with High Risk Prostate Cancer (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)
In a new study led by researchers at Brigham and Women's Hospital, investigators looked at men with aggressive prostate cancer who were treated with radiation as well as the case volume of the facility at which they were treated. They found that receiving radiation at a facility that treats a high volume of prostate cancer patients with radiation was associated with improved overall survival. Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospital Cancer Center is ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 14, 2016 Category: Cancer & Oncology Source Type: news

Research in the News: Key Protein in Pancreatic Cancer Growth May Also be Its Undoing (Yale Cancer Center/Smilow Cancer Hospital)
Yale researchers have found that the overexpression of a protein called renalase in pancreatic cancer plays a critical role in spurring the cancer's growth while also providing a possible new target for attacking the tumors it helps develop. The findings were described in the March 14th online issue of Scientific Reports. Yale Cancer Center/Smilow Cnacer Hospital is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 14, 2016 Category: Cancer & Oncology Source Type: news

Anticancer Drug Restores Hearing in Some Patients with Neurofibromatosis (The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins)
... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 14, 2016 Category: Cancer & Oncology Source Type: news

New Agent Overcomes Drug Resistance in HER2-Positive Breast Cancer, Preclinical Study Shows (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)
A type of breast cancer that often develops resistance to targeted therapies was driven back into remission in mice by a drug that blocks the division of cancer cells, a new study led by researchers at Dana-Farber Cancer Institute has found. The results, reported in Cancer Cell, prompted investigators to launch a clinical trial of the new agent in women with a metastatic form of this cancer, known as HER2-positive breast cancer. Dana-Farber/Brigham and Women's Cancer Center | Massachusetts Ge... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 14, 2016 Category: Cancer & Oncology Source Type: news

Rattled by Drug Price Increases, Hospitals Seek Ways to Stay on Guard (
This article mentions a number of NCCN Member Institutions, including Case Comprehensive Cancer Center/University Hospitals Seidman Cancer ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 13, 2016 Category: Cancer & Oncology Source Type: news

Financial Burden of Cancer Can Harm Quality of Life (Fox News Health)
This article features commentary from a physician at University of Michigan Comprehensive Cancer Center-one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 13, 2016 Category: Cancer & Oncology Source Type: news

Neurofeedback Reduces Pain, Increases Quality of Life for cancer Patients Suffering from Chemotherapy-Induced Neuropathy (The University of Texas MD Anderson Cancer Center)
A new study from The University of Texas MD Anderson Cancer Center evaluating the use of neurofeedback found a decrease in the experience of chronic pain and increase quality of life in patients with neuropathic pain. The University of Texas MD Anderson Cancer Center is one of the 26 NCCN Member Institutions. ... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 12, 2016 Category: Cancer & Oncology Source Type: news

Certain Biopsy Method Tied to Better Outcomes after Kidney Cancer (U.S. NewsandWorld Report)
A type of lab test called a "core-needle biopsy," performed on tissue taken from a mass on a kidney, may be better for certain kidney cancer patients, new research suggests. The study involved people with a renal (kidney) cell carcinoma-the most common type of kidney cancer in adults. Researchers led by Dr. Rosaleen Parsons, of Fox Chase Cancer Center in Philadelphia-one of the 26 NCCN Member Institutions, noted that incidence and death rates of the disease have climbed in recent de... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 12, 2016 Category: Cancer & Oncology Source Type: news

Who Really Needs a Colonoscopy? (The Philadelphia Inquirer)
In the United States, several cancer experts said more Americans likely would get screened if their doctors offered them options. The most commonly suggested alternative: a simple take-at-home stool test that may suffice for healthy people who have no family history of the disease and aren't suffering from irritable bowel syndrome. If done annually, fecal immunochemical tests (FIT) have a strong track record for detecting hidden blood in the stool, an early sign of malignancy. A FIT do... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 11, 2016 Category: Cancer & Oncology Source Type: news

When Gene Tests for Breast Cancer Reveal Grim Data but No Guidance (
This article features commentary from experts at three NCCN Member Institutions-Dana-Farber/Brigham and Women's Cancer Center | Massachusetts General Hospita... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 11, 2016 Category: Cancer & Oncology Source Type: news

The Rate of Double Mastectomies Has Tripled In 10 Years: Study (
Cancer treatments, especially for breast cancer, have become remarkably sophisticated and are responsible for saving millions of lives. But in some cases, the inclination toward surgery in one or both breasts may be unnecessary-or at least not without major complications. That has a growing number of experts saying that the standard ways in which breast cancer is treated verges on overkill-and needs to be rethought. A new study published Friday in the Annals of Surgery adds nuance to the picture... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 11, 2016 Category: Cancer & Oncology Source Type: news

In Defense of the Negative Result (Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance)
We've all heard the story. An experimental cancer treatment shows promise in preliminary testing, and then larger trials find no actual improvement over the standard of care. There's a positive side to negative results, those clinical trials where the treatment under study is worse or, at least, no better than currently available therapies, said Dr. Joseph Unger, a biostatistician at Fred Hutchinson Cancer Research Center. He and his colleagues found that, among all the publications resulting... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 10, 2016 Category: Cancer & Oncology Source Type: news

Unpacking Space Radiation Key to Controlling Astronaut and Potentially Earthbound Cancer Risk (University of Colorado Cancer Center)
NASA limits an astronaut's radiation exposures to doses that keep their added risk of fatal cancer below 3 percent. Unfortunately, that ceiling restricts the time an astronaut may spend in space, which in turn restricts the ability to perform longer missions, say a mission to Mars. Now a network of research laboratories seeks to understand the mechanisms and effects of space radiation with the goal of predicting and preventing radiation-induced cancers, both in space and at home. One of these la... (Source: National Comprehensive Cancer Network)
Source: National Comprehensive Cancer Network - March 10, 2016 Category: Cancer & Oncology Source Type: news