Study Finds Mechanism by which Obesity Promotes Pancreatic and Breast Cancer (Dana-Farber/Brigham and Women’s Cancer Center | Massachusetts General Hospital Cancer Center)

Massachusetts General Hospital investigators may have uncovered a novel mechanism behind the ability of obesity to promote cancer progression. In their report published online in the journal Clinical Cancer Research, the research team describes finding an association between obesity and an overabundance of a factor called PlGF (placental growth factor) and that PlGF's binding to its receptor VEGFR-1, which is expressed on immune cells within tumors, promotes tumor progression. Their findings in...
Source: National Comprehensive Cancer Network - Category: Cancer & Oncology Source Type: news