ASCO: NSCLC Therapy Guided by RRM1, ERCC1 Expression Yields No Survival Difference
Guiding treatment for non–small-cell lung cancer (NSCLC) using expression levels of the proteins RRM1 and ERCC1 led to no difference in either progression-free or overall survival, according to a study presented at the American Society of Clinical Oncology (ASCO) annual meeting. (Source: Cancer Network)
Source: Cancer Network - June 4, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Long-Term Tamoxifen Benefit for Breast Cancer Confirmed
Women diagnosed with estrogen-receptor (ER)-positive breast cancer who took tamoxifen for 10 years as adjuvant therapy had lower risk of late recurrence and lower risk of death compared to those who took the drug for 5 years. These results corroborate the findings of the international ATLAS trial. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Sulforaphane in Prostate Cancer Found Worthy of Further Investigation
Treatment with 200 µmol per day of sulforaphane for 20 weeks was “feasible, safe,” and inhibited histone deacetylase (HDAC) function in a single-arm study of 20 patients who had non-castrate biochemical (PSA)-recurrence of prostate cancer despite surgery or radiation. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Pomalidomide New Standard of Care in Heavily Pretreated, Relapsed Multiple Myeloma
Pomalidomide in combination with low-dose dexamethasone had a highly significant benefit on progression-free survival and overall survival compared with single-agent high-dose dexamethasone in patients with relapsed or refractory multiple myeloma, according to updated results of the MM-03 trial presented at the ASCO 2013 Annual Meeting. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: For Painful Bone Mets, Single Fraction Irradiation Noninferior to Multiple-Fraction Therapy
The use of a single 8 Gy fraction of re-irradiation for the treatment of painful bone metastases was noninferior to multiple fractions, according to the results of the NCIC CTG SC.20 trial presented at the ASCO 2013 Annual Meeting in Chicago. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: DNR Completion at End of Life Influenced by Perception of Caregiver Support
Results of a new study indicated that patients with terminal cancer are more likely to have completed a do-not-resuscitate order when they prefer, and believe that their caregiver prefers, comfort at the end of life. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Prolonged Survival in Multiple Myeloma Predicted Using Deep Sequencing
Multiparameter flow cytometry and deep sequencing were both able to accurately identify patients with multiple myeloma who were negative for minimal residual disease, a factor that was found to better predict prolonged survival compared with complete response as measured by traditional response criteria. (Source: Cancer Network)
Source: Cancer Network - June 3, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Preview of the Prostate Cancer Sessions
Ahead of the 2013 ASCO meeting we highlight some of this year's prostate cancer sessions, many of which focus on how best to use the new agents that have been approved recently, and look into the new drugs and combinations being presented from early trials. (Source: Cancer Network)
Source: Cancer Network - May 30, 2013 Category: Cancer & Oncology Source Type: news

Study: Recurrent Heartburn Ups Risk for Throat Cancer
A new population-based study of never-smokers shows those with gastric reflux are more likely to be diagnosed with cancers of the throat, including the voice box. (Source: Cancer Network)
Source: Cancer Network - May 29, 2013 Category: Cancer & Oncology Source Type: news

ASCO: Neoadjuvant Therapy Options and Clinical Trials in Breast Cancer
Ahead of the ASCO 2013 meeting we discuss neoadjuvant therapy options and clinical trials in breast cancer, as well as the opportunities for targeted therapies in post-neoadjuvant trials. (Source: Cancer Network)
Source: Cancer Network - May 29, 2013 Category: Cancer & Oncology Source Type: news

Cannabis Linked to Decreased Bladder Cancer Risk
The use of cannabis among men has been linked to a significantly decreased risk for bladder cancer, according to a recent study; however, no cause and effect association has been found. (Source: Cancer Network)
Source: Cancer Network - May 28, 2013 Category: Cancer & Oncology Source Type: news

AUA Guidelines for Metastatic Castration-Resistant Prostate Cancer
The AUA recently released its first set of treatment guidelines addressing the treatment of men with metastatic castration-resistant prostate cancer (mCRPC) at its 2013 Annual Meeting. The guidelines were released to address the increasingly complex treatment landscape available for patients with mCRPC. (Source: Cancer Network)
Source: Cancer Network - May 28, 2013 Category: Cancer & Oncology Source Type: news

Conservative vs Aggressive Treatment in Older Prostate Cancer Patients
Survival data of prostate cancer patients 70 and older show that those with three or more comorbidities and low- or intermediate-risk prostate cancer are less likely to die from prostate cancer than another health issue. But those with aggressive, high-risk disease are more likely to die from their prostate cancer. (Source: Cancer Network)
Source: Cancer Network - May 28, 2013 Category: Cancer & Oncology Source Type: news

Breast Cancer Screening, Risk, and Options for High-Risk Women
We speak with two experts to discuss breast cancer risk, genetics, and prevention options available to women at high risk of developing breast and ovarian cancer. (Source: Cancer Network)
Source: Cancer Network - May 23, 2013 Category: Cancer & Oncology Source Type: news

A 52-Year-Old Man Presents With an Erythematous Lesion
A 52-year-old man presented with an erythematous lesion in the axilla of unknown duration. Surgical excision was performed. What is your diagnosis? (Source: Cancer Network)
Source: Cancer Network - May 22, 2013 Category: Cancer & Oncology Source Type: news