Management of Lymph Node–Positive Prostate Cancer: The Role of Surgery and Radiation Therapy
Current evidence for the management of lymph node–positive prostate cancer suggests both a disease-control and survival benefit to systemic ADT plus surgery and radiation. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

A Large Cystic Pancreatic Mass in a 45-Year-Old Female
The patient is an otherwise healthy 45-year-old female who presented to her primary care physician with 6 weeks of increasing left upper quadrant abdominal pain with radiation to the back. She underwent an abdominal ultrasound, which revealed a large cystic abdominal mass. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

High-Dose Interleukin-2: Is It Still Indicated for Melanoma and RCC in an Era of Targeted Therapies?
In this review, we examine the currently approved options available for these disease processes, including the newer agents and selected combinatorial approaches under investigation, and we attempt to identify the role of high-dose IL-2 in the context of current clinical practice. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

Can I Pray With You?
A 40-year-old woman with no significant family history of cancer came to me for a second opinion about her widely metastatic infiltrating gastric cancer. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

Clarifying the Use of Ruxolitinib in Patients With Myelofibrosis
In this article, we provide updated data on ruxolitinib therapy for patients with myelofibrosis and offer expert opinion on the appropriate use of this agent in the community practice. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

Muscle Density Linked to Survival in Metastatic RCC
A high skeletal muscle density has been linked to a twofold prolonged survival in patients with metastatic renal cell carcinoma compared with patients with low muscle density, according to a new study. (Source: Cancer Network)
Source: Cancer Network - July 15, 2013 Category: Cancer & Oncology Source Type: news

EUTOS Score Validated for Predicting Treatment Outcomes With TKI Therapy
A new study validates a simple prognostic score, the EUTOS score, as a useful tool in predicting the therapeutic effects of TKIs for chronic myeloid leukemia. (Source: Cancer Network)
Source: Cancer Network - July 12, 2013 Category: Cancer & Oncology Source Type: news

LUX-LUNG 3 and 4 Show Afatinib Effective in EGFR-mutated NSCLC
Two new studies show that afatinib, an orally bioavailable ERBB family blocker, could be effective in patients with non–small-cell lung cancer (NSCLC) who progressed on other therapies and in patients with advanced lung adenocarcinomas and EGFR mutations. (Source: Cancer Network)
Source: Cancer Network - July 12, 2013 Category: Cancer & Oncology Source Type: news

FDA Approves Afatinib for Advanced Lung Cancer
The FDA approved afatinib (Gilotrif) as a first-line therapy for patients with metastatic non-small-cell lung cancer whose tumors harbor certain mutations in the epidermal growth factor receptor gene. (Source: Cancer Network)
Source: Cancer Network - July 12, 2013 Category: Cancer & Oncology Source Type: news

Ponatinib Receives Marketing Authorization in Europe for CML and Ph+ ALL
ARIAD has received marketing authorization from the European Commission for ponatinib (Iclusig) in chronic myeloid leukemia and acute lymphoblastic leukemia. (Source: Cancer Network)
Source: Cancer Network - July 12, 2013 Category: Cancer & Oncology Source Type: news

ASCO Adds New Drug to Breast Cancer Prevention Guidelines
The American Society of Clinical Oncology (ASCO) has updated its guidelines on treating women at high risk of developing breast cancer with pharmacologic drugs. (Source: Cancer Network)
Source: Cancer Network - July 10, 2013 Category: Cancer & Oncology Source Type: news

Developing Novel Treatments Using the AML Genome
In this interview we discuss acute myeloid leukemia therapy approaches and new molecular targets based on genetic analyses of the disease with a leukemia expert. (Source: Cancer Network)
Source: Cancer Network - July 10, 2013 Category: Cancer & Oncology Source Type: news

Pertuzumab Granted Priority Review for Neoadjuvant HER2-Positive Breast Cancer
Last week, the FDA announced that it would grant priority review to pertuzumab (Perjeta), as a neoadjuvant treatment for women with HER2-positive early-stage breast cancer. (Source: Cancer Network)
Source: Cancer Network - July 9, 2013 Category: Cancer & Oncology Source Type: news

Role of Aspirin in Colorectal Cancer Prevention and Treatment
In this interview we discuss the role of aspirin in colorectal cancer prevention and treatment. Various studies have suggested that a daily aspirin pill can help prevent certain types of cancers. Other studies suggest that there may even be a role for aspirin in treating cancer. (Source: Cancer Network)
Source: Cancer Network - July 9, 2013 Category: Cancer & Oncology Source Type: news

Particulate Air Pollution Contributes to Lung Cancer Risk in Huge European Study
A study including 17 cohorts with a total of more than 300,000 individuals found that ambient air pollution of various types contributes to lung cancer incidence across nine European countries. (Source: Cancer Network)
Source: Cancer Network - July 9, 2013 Category: Cancer & Oncology Source Type: news