Nonseminomatous Germ Cell Tumor of Testis and Interrupted Treatment
A 22-year-old man presented to the emergency department with a 5-cm painful testicular mass that had increased in size over the previous month. Tumor markers were drawn and an inguinal orchiectomy was performed. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

Oral Oncolytics: Part 1—Financial, Adherence, and Management Challenges
The management of patients receiving treatment with oral oncolytics presents challenges such as cost, adherence, monitoring of side effects, and safe handling. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

First-Line Treatment for Patients With CML in Chronic Phase: Second-Generation TKIs Are the Therapy of Choice
How often do we choose the “second best” treatment as initial therapy for our patients with cancer? The management of chronic myeloid leukemia should be no different. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

First-Line Treatment for Patients With CML in Chronic Phase: Why Imatinib Is an Appropriate Choice
I am very comfortable in using imatinib as initial therapy in most patients who present in chronic phase, with the possible exception of patients with more advanced disease and higher Sokal scores. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

The Impact of Molecular Testing on Treatment of Cancer of Unknown Primary Origin
The preponderance of data support the accuracy of molecular assay diagnoses in about 80% to 90% of patients with known advanced primary cancers and in patients with cancer of unknown primary origin. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

Announcing a New Series: Understanding Unusual Dysproteinemias
In a new series, beginning this month and running into early 2014, experts on five “unusual dysproteinemias” will share their insights into diagnosis and management. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

Unusual Myelomas: A Review of IgD and IgE Variants
Although survival of patients with IgD or IgE multiple myeloma is shorter in comparison to those with IgG or IgA multiple myeloma, the outcome for patients with IgD and IgE subtypes is improving with the use of novel agents and autologous transplantation. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

ACR Appropriateness Criteria® Localized Nodal Indolent Lymphoma
The present guidelines review epidemiology, pathology, presentation, workup, staging, prognostic factors, and treatment options for patients with localized nodal indolent lymphoma, with an emphasis on radiation guidelines, including radiation dose, field design, and radiation techniques. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

Use of Molecular Biomarkers to Inform Adjuvant Therapy for Colon Cancer
In this review, we will discuss adjuvant chemotherapy in non-metastatic colon cancer, the existing prognostic and predictive molecular biomarkers in the field, and how to integrate these molecular biomarkers into the decision about whether to administer adjuvant therapy. (Source: Cancer Network)
Source: Cancer Network - August 15, 2013 Category: Cancer & Oncology Source Type: news

One-Two Punch May Improve Cancer Treatment Results
A new study demonstrates a way to exploit a metabolic vulnerability of senescent cells. The strategy provides evidence for an anticancer approach that targets a cellular process or condition of the cell rather than a distinct molecular pathway. (Source: Cancer Network)
Source: Cancer Network - August 14, 2013 Category: Cancer & Oncology Source Type: news

Some Blood Pressure Drugs Increase Breast Cancer Risk
Use of calcium-channel blockers for treatment of high blood pressure for more than 10 years can increase the risk of breast cancer for women after menopause, a new study shows. (Source: Cancer Network)
Source: Cancer Network - August 13, 2013 Category: Cancer & Oncology Source Type: news

Patterns of Recurrence Differ by Breast Cancer Node-Negative Subtype
A study defining patterns of recurrence in node-negative breast cancer patients could help guide surveillance recommendations and future therapeutic approaches. (Source: Cancer Network)
Source: Cancer Network - August 12, 2013 Category: Cancer & Oncology Source Type: news

Adrenal Lesion Discovered in 50-Year-Old Patient
A 50-year-old patient had an abdomen MRI to evaluate an adrenal lesion detected during the work-up of abdominal pain. Based on the images from the abdomen MRI, what is your diagnosis? (Source: Cancer Network)
Source: Cancer Network - August 12, 2013 Category: Cancer & Oncology Source Type: news

Robotic Ultrasound Beneficial for Robotic Partial Nephrectomy
Surgeons saw advantages in robotic, over laparoscopic, ultrasound probes during robotic partial nephrectomy, and similar perioperative outcomes and margin rates. (Source: Cancer Network)
Source: Cancer Network - August 12, 2013 Category: Cancer & Oncology Source Type: news

Post-Orchiectomy Surveillance Is Sufficient for Men With Stage I Seminoma
At the 2013 ASCO meeting, investigators of a large Danish study have concluded that surveillance alone following surgery for stage I seminoma is sufficient, sparing patients in this setting from the unnecessary expense and associated toxicities of chemotherapy and radiation treatment. (Source: Cancer Network)
Source: Cancer Network - August 10, 2013 Category: Cancer & Oncology Source Type: news