The impact of the prevention strategies on the indirect effects of CMV infection in solid organ transplant recipients
Abstract: Transplant recipients receiving immunosuppressive therapy are at increased risk of active cytomegalovirus (CMV) infection and disease. Without appropriate prophylaxis, as many as 80% of solid organ transplant recipients may experience CMV infection. In addition to the direct effects of CMV, infection may be associated with a range of indirect effects, including an increase in risk of other infections, as well as a higher incidence of rejection, graft loss and death. The indirect effects of CMV infection can vary depending on the transplanted organ. For example, CMV-infected kidney transplant recipients may be at ...
Source: Transplantation Reviews - January 31, 2014 Category: Transplant Surgery Authors: Antonio Roman, Nicolás Manito, Josep Maria Campistol, Valentín Cuervas-Mons, Luis Almenar, Manuel Arias, Fernando Casafont, Domingo del Castillo, María G. Crespo-Leiro, Juan F. Delgado, J. Ignacio Herrero, Paloma Jara, José M. Morales, Mercedes Navarr Tags: Independent Articles Source Type: research
Obesity, metabolic syndrome and diabetes mellitus after renal transplantation: Prevention and treatment
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 30, 2013 Category: Transplant Surgery Authors: Karl Martin Wissing, Lissa Pipeleers Tags: Special Section Source Type: research
Obesity, metabolic syndrome and diabetes mellitus after renal transplantation: Prevention and treatment
Abstract: The prevalence of the metabolic syndrome in dialysis patients is high and further increases after transplantation due to weight gain and the detrimental metabolic effects of immunosuppressive drugs. Corticosteroids cause insulin resistance, hyperlipidemia, abnormal glucose metabolism and arterial hypertension. The calcineurin inhibitor tacrolimus is diabetogenic by inhibiting insulin secretion, whereas cyclosporine causes hypertension and increases cholesterol levels. Mtor antagonists are responsible for hyperlipidemia and abnormal glucose metabolism by mechanisms that also implicate insulin resistance. The metab...
Source: Transplantation Reviews - December 30, 2013 Category: Transplant Surgery Authors: Karl Martin Wissing, Lissa Pipeleers Tags: Special Section Source Type: research
Malignancies: Pre and post transplantation strategies
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 16, 2013 Category: Transplant Surgery Authors: Meteb AlBugami, Bryce Kiberd Tags: Special Section Source Type: research
Bone and mineral disorders after kidney transplantation: Therapeutic strategies
(Source: Transplantation Reviews)
Source: Transplantation Reviews - December 16, 2013 Category: Transplant Surgery Authors: Miklos Z. Molnar, Mohamed S. Naser, Connie M. Rhee, Kamyar Kalantar-Zadeh, Suphamai Bunnapradist Tags: Special Section Source Type: research
