Tyrosine ‐Kinase Inhibitors for Treatment in Hemodialysis Patients on Kidney Transplant Waiting List. Comment on: Nakai et al.
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - September 7, 2017 Category: Hematology Authors: Giorgia Comai, Maria Cappuccilli, Giuseppe Cianciolo, Gaetano La Manna Tags: Letter to the Editor Source Type: research
Characteristics and Prognosis of Hepatocellular Carcinoma in Japanese Patients Undergoing Dialysis
Abstract
Patients with end‐stage renal disease who are undergoing dialysis may be at high risk of developing hepatocellular carcinoma (HCC). We investigated the characteristics and prognosis of HCC in patients undergoing dialysis in Japan. Patients characteristics, progression of HCC at diagnosis, and survival rates after diagnosis were compared between 108 HCC patients undergoing dialysis and 526 non‐dialysis patients followed up at liver center. The comparisons were also performed after adjusting for patient age, gender, platelet count, and etiology using propensity‐score matching. HCC was more advanced in patients...
Source: Therapeutic Apheresis and Dialysis - September 7, 2017 Category: Hematology Authors: Hidenori Toyoda, Atsushi Hiraoka, Toshifumi Tada, Kojiro Michitaka, Koichi Takaguchi, Kunihiko Tsuji, Ei Itobayashi, Daichi Takizawa, Masashi Hirooka, Yohei Koizumi, Hironori Ochi, Koji Joko, Yoshiyasu Kisaka, Yuko Shimizu, Kazuto Tajiri, Joji Tani, Tatsu Tags: Original Article Source Type: research
The ISFA wishes to acknowledge the following 2016 Corporate Sponsors
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Tags: Corporate Sponsors Source Type: research
Upcoming Meetings Therapeutic Apheresis and Dialysis August 2017
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Tags: Communication Source Type: research
Decreased Expression of Thrombomodulin in Endothelial Cells by Fibroblast Growth Factor ‐23/α‐Klotho
This study indicates a possible mechanism by which excessive levels of FGF23 are involved in endothelial TM disruption, which has been implicated as a potential cardiovascular risk factor in patients with CKD, especially in HD patients. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Authors: Kenji Tanaka, Tancharoen Salunya, Yoshihiro Motomiya, Yasuki Motomiya, Yoko Oyama, Munekazu Yamakuchi, Ikuro Maruyama Tags: Original Article Source Type: research
Is High ‐Volume Online Hemodiafiltration Associated With Malnutrition?
Abstract
Chronic malnutrition is a common problem in patients with end‐stage renal disease on hemodialysis. Some studies have reported albumin loss into dialysis fluid during postdilution online hemodiafiltration (OL‐HDF). The aim of the study was to assess the nutritional status of patients on high‐volume OL‐HDF and to demonstrate that higher convective clearances are not associated with malnutrition due to possible loss of nutrients with ultrafiltration. Demographic and clinical data, corporal composition with bioimpedance spectroscopy, dialysis features, albumin loss into dialysis fluid and laboratory parameters...
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Authors: Nicol ás Macías, Almudena Vega, Soraya Abad, Alba Santos, Santiago Cedeño, Tania Linares, Ana María García‐Prieto, Inés Aragoncillo, Claudia Yuste, Juan Manuel López‐Gómez Tags: Original Article Source Type: research
RAS Inhibitor Is Not Associated With Cardiovascular Benefits in Patients Undergoing Hemodialysis in Japan
The objective of this study was to investigate the association of RAS inhibitor usage with CVEs in patients enrolled in the Dialysis Outcomes Practice Pattern Study in Japan (J‐DOPPS). Association of RAS inhibitor prescription with outcomes including all‐cause death, death caused by CVE, and hospitalization due to cardiac failure was investigated by using a multivariable Cox proportional hazards model. Of the 3848 patients enrolled, 1784 (45%) patients were treated by RAS inhibitors. After adjusting for potential cofounders by Cox proportional hazards models, we found a statistically insignificant but positive associat...
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Authors: Masahide Mizobuchi, Hiroaki Ogata, Yoshihiro Onishi, Shingo Fukuma, Tadao Akizawa, Shunichi Fukuhara Tags: Original Article Source Type: research
Issue Information
No abstract is available for this article. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Tags: Issue Information Source Type: research
Early Graft Loss in Two Recipients of Mate Kidneys From the Same Donor With Diabetic Nephropathy
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 14, 2017 Category: Hematology Authors: Daigo Okada, Masayoshi Okumi, Kazunari Tanabe Tags: Letter to the Editor Source Type: research
Hemodialysis Decreases the Concentration of Accumulated Plant Phenols in the Plasma of Patients on Maintenance Dialysis: Influence of Residual Renal Function
Abstract
Plant phenols may accumulate in end‐stage kidney disease. The effect of hemodialysis on their plasma concentration remains poorly determined. Contingent on concentration, health‐promoting or noxious effects occur; therefore, we assessed plasma concentration in hemodialyzed patients. In total, 21 maintenance hemodialyzed patients with diuresis < 500 mL per day (with oliguria), nine hemodialyzed patients with diuresis ≥ 500 mL per day (without oliguria) and 31 healthy volunteers were included. Nine phenolic acids were identified with high‐performance liquid chromatography and total polyphenol concentr...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Piotr Jan Nowak, Radoslaw Wilk, Anna Prymont ‐Przyminska, Anna Zwolinska, Agata Sarniak, Anna Wlodarczyk, Jeffrey Graft‐Johnson, Beata Mamelka, Anna Zasowska‐Nowak, Piotr Bartnicki, Dariusz Nowak, Michal Nowicki Tags: Original Article Source Type: research
Parathyroid Nodular Hyperplasia and Responsiveness to Drug Therapy in Renal Secondary Hyperparathyroidism: An Open Question
Abstract
The goal of the pharmacological therapy in secondary hyperparathyroidism (SHPT) is to reduce serum levels of parathyroid hormone and phosphorus, to correct those of calcium and vitamin D, to arrest or reverse the parathyroid hyperplasia. However, when nodular hyperplasia or an autonomous adenoma develops, surgery may be indicated. We reviewed the literature with the aim of defining if the echographic criteria predictive of unresponsiveness of SHPT to calcitriol therapy are valid also in the cinacalcet era and if drug therapy may reverse nodular hyperplasia of parathyroid gland (PTG). The responsiveness to therapy ...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Carlo Vulpio, Maurizio Bossola Tags: Review Source Type: research
Prevalence of and Predictive Factor for Abdominal Aortic Calcification in Thai Chronic Kidney Disease Patients
Abstract
Presence and severity of cardiovascular calcifications strongly predict cardiovascular morbidity and mortality in patients with CKD. This multicenter, cross‐sectional study primarily aimed to determine prevalence of abdominal aortic calcification (AAC) detected by plain lateral abdominal radiograph, and secondarily aimed to assess predictive factors for AAC. Patients (N = 1500), aged 18–70 years, with CKD stages 3–5D for ≥3 months prior to evaluation, were enrolled at 24 study centers in Thailand; 54.3% were non‐dialysis patients. The prevalence of AAC was 70.6% and 70.8% in non‐dialysis and dialys...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Dusit Lumlertgul, Surasak Kantachuvesiri, Somboon Apichaiyingyurd, Worapot Treamtrakanpon, Manoch Rattanasompattikul, Pongsathorn Gojaseni, Prasert Thanakitcharu, Thananda Trakarnvanich, Ussanee Poonvivatchaikarn, Kriengsak Vareesangthip, Tags: Original Article Source Type: research
FGF23 Level and Intima ‐Media Thickness Are Elevated From Early Stages of Chronic Kidney Disease
Abstract
Considering high cardiovascular (CV) risk in chronic kidney disease (CKD), the aim of this cross‐sectional study was to assess the association between carotid intima‐media thickness (IMT) and fibroblast growth factor (FGF) 23 as important players in CV pathophysiology. Eighty‐seven patients with mean estimated glomerular filtration rate 40.1 mL/min per 1.73 m2 were involved. FGF23 and IMT were elevated from early stages of CKD. Mean IMT value was 1.10 ± 0.20 mm, being significantly elevated starting from early CKD, showing no correlation with FGF23 (r = −0.01, P = −0.91). Unlike the FGF23 level...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Andreja Figurek, Goce Spasovski, Snjezana Popovic ‐Pejicic Tags: Original Article Source Type: research
Red Blood Cell Distribution Width is Associated With All ‐Cause and Cardiovascular Mortality in Hemodialysis Patients
In conclusion, higher RDW value was a significant predictor for all‐cause and cardiovascular mortality in patients undergoing maintenance hemodialysis. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Hirotaka Fukasawa, Kento Ishibuchi, Mai Kaneko, Hiroki Niwa, Hideo Yasuda, Hiromichi Kumagai, Ryuichi Furuya Tags: Original Article Source Type: research
Impact of Statins on Arteriovenous Fistulas Outcomes: A Meta ‐Analysis
Abstract
Statins are effective lipid‐lowering drugs with beneficial pleiotropic effects for vascular remodeling processes, statins may have a beneficial effect on the function of arteriovenous fistulas (AVFs) in hemodialysis (HD) patients. Therefore, we performed this systematic review to assess the protective effects of statin therapy in HD patients. The randomized controlled trials (RCTs) or quasi‐RCTs and retrospective cohort studies (RCS) of statin therapy for the function of AVFs in HD patients were searched from multiple databases. Relevant studies were screened according to predefined inclusion criteria and then...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Qingsong Wan, Li Li, Shikun Yang, Fenfen Chu Tags: Original Article Source Type: research
