Inhibition of Inflammatory Cytokines and Induction of Myeloid ‐Derived Suppressor Cells by the Effects of Granulocyte and Monocyte Adsorption Apheresis
Abstract Pro‐inflammatory cytokines are involved in the pathogenesis of inflammatory skin diseases attributable to activated neutrophils and macrophages. Myeloid‐derived suppressor cells (MDSCs) play an important role in the regulation of the immune response and possess strong immunosuppressive and anti‐inflammatory properties. Granulocyte and monocyte adsorption apheresis (GMA), an extracorporeal apheresis instrument featuring columns containing cellulose acetate (CA) beads, is designed to remove pathogenic myeloid lineage cells. The purpose of this study was to investigate the effects of GMA on cytokine production ...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Masanao Sakanoue, Yuko Higashi, Takuro Kanekura Tags: Original Article Source Type: research

Generalized Pustular Psoriasis With IL ‐36 Receptor Antagonist Mutation Successfully Treated With Granulocyte and Monocyte Adsorption Apheresis Accompanied by Reduced Serum IL‐6 Level
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Asami Fujii, Hidenori Ohnishi, Mariko Seishima Tags: Letter to the Editor Source Type: research

Occult Hepatitis B Virus Infection With Increased Virus DNA Levels in a Chronic Hemodialysis Patient
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Yoshitaka Koshino, Yasuyuki Shinozaki, Takashi Wada Tags: Letter to the Editor Source Type: research

Decongestion Versus Cytokine Clearance in Acute Heart Failure: Not All that Glitters is Gold
(Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Abhilash Koratala, Amir Kazory Tags: Letter to the Editor Source Type: research

Bartonellosis in Chronic Kidney Disease: An Unrecognized and Unsuspected Diagnosis
Abstract Systemic cat scratch disease or bartonellosis is a clinical entity caused by Bartonella henselae, which manifests with necrotizing granulomas in visceral organs. The cat flea, Ctenocephalides felis, is the vector responsible for horizontal transmission of the disease from cat to cat, and its bite can also infect humans. In immunocompromised patients including chronic kidney disease and renal transplant recipients, it can cause persistent and disseminated cat scratch disease. The aim of this paper is to perform a systematic review of the studies that have addressed the diagnostic methods of cat scratch disease in c...
Source: Therapeutic Apheresis and Dialysis - August 1, 2017 Category: Hematology Authors: Fateme Shamekhi Amiri Tags: Review Source Type: research