Decreased Expression of Thrombomodulin in Endothelial Cells by Fibroblast Growth Factor ‐23/α‐Klotho

This study indicates a possible mechanism by which excessive levels of FGF23 are involved in endothelial TM disruption, which has been implicated as a potential cardiovascular risk factor in patients with CKD, especially in HD patients.

Source: Therapeutic Apheresis and Dialysis - August 17, 2017 Category: Hematology Authors: Kenji Tanaka, Tancharoen Salunya, Yoshihiro Motomiya, Yasuki Motomiya, Yoko Oyama, Munekazu Yamakuchi, Ikuro Maruyama Tags: Original Article Source Type: research