The evolution of antivascular endothelial growth factor agents for the treatment of neovascular age-related macular degeneration
Publication date: March 2014 Source:Taiwan Journal of Ophthalmology, Volume 4, Issue 1 Author(s): Chang-Hao Yang (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Role of genetic factors in the pathogenesis of exudative age-related macular degeneration
Publication date: Available online 6 May 2014 Source:Taiwan Journal of Ophthalmology Author(s): Peng Zhou , Xiao-Xin Li Exudative age-related macular degeneration (AMD) is one of the leading causes of irreversible blindness worldwide. Many recent genetic association studies on large case–control cohorts have helped in drawing an outline of the pathogenesis of AMD. The majority of the associations observed in oxidative stress and lipid peroxidation (complement factor H or CFH), complement (CFH, C3, complement factor I, C2, complement factor B), and neovascularization (vascular endothelial growth factor A, high-tempe...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Current concepts and cutting-edge techniques in myopic macular surgeries
Publication date: Available online 10 May 2014 Source:Taiwan Journal of Ophthalmology Author(s): Yasushi Ikuno Myopic foveoschisis and macular hole with a retinal detachment are two major diseases associated with posterior staphyloma that are specific to high myopia. The pathogenesis is a combination of various types of traction from the vitreous cortex, epiretinal membrane (ERM), internal limiting membrane (ILM), and microvessels. Foveoschisis typically starts with retinoschisis, and a retinal detachment subsequently develops as a result of traction on the inner retina. The stress on the fovea eventually opens a smal...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Severe ocular complications following facial calcium hydroxylapatite injections: Two case reports
We report two cases of severe ocular complications after nasal cosmetic enhancement. Both cases had poor visual outcomes in spite of emergency management. The second patient is a rare case with bilateral anterior ischemic optic neuropathy after dermal soft-tissue augmentation. The visual outcome was correlated with the location and the extent of the arterial embolization. Unfortunately, there is still no standard treatment protocol for vision-threatening complications. Clinicians should always keep in mind that embolic arterial occlusion may occur after augmentation. (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Post-chemotherapy bilateral limbal stem cell deficiency
We report an extremely rare case of bilateral total limbal stem cell deficiency (LSCD) induced by long-term systemic chemotherapy for squamous cell carcinoma of the lung, and the outcomes of bilateral keratolimbal allograft transplantation (KLAT) in such a case. A 34-year-old male patient had underlying disease of squamous cell carcinoma in the right upper lung with extensive mediastinum and lymph node metastasis and received a series of systemic chemotherapy, including a combination of vinorelbine and cisplatin and a combination of gemcitabine, cisplatin, and docetaxel. According to clinical manifestations of ocular surfa...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Hybrid monovision therapy in a patient with retinitis pigmentosa
Publication date: June 2014 Source:Taiwan Journal of Ophthalmology, Volume 4, Issue 2 Author(s): Shao-Yu Lei , Chien-Liang Wu A 41-year-old female was diagnosed with retinitis pigmentosa (RP) after bilateral implantation of multifocal intraocular lenses (IOLs). Due to persistent dissatisfaction with her visual performance, she came to our hospital for medical help. We exchanged the multifocal IOL in the dominant eye with a monofocal IOL (hybrid monovision therapy), and the visual inconvenience was alleviated to a large extent. To our knowledge, this is the first case report on the effect of hybrid monovision therapy ...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Management of keratoconus and post-laser-assisted in situ keratomileusis ametropia and keratectasia with mini-scleral lenses—Three case reports
In conclusion, mini-scleral lenses provide better comfort and vision in patients with keratoconus and post-LASIK keratectasia and ametropia. (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Intravitreal injection of triamcinolone acetonide in nonarteritic anterior ischemic optic neuropathy
Conclusion Some patients with NAION may improve with IVITA treatment. Further randomized controlled clinical trials are needed. (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Smartphone fundoscopy for retinopathy of prematurity
Conclusion Fundus photographs of acceptable diagnostic quality can be obtained in ROP patients conveniently and inexpensively using a portable hand-held smartphone. It might be a useful tool in documentation, education, consultation, and telemedicine in ROP. (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Outcomes of combination therapy with dexamethasone implant and bevacizumab in macular edema related to vascular occlusions
Conclusion This study demonstrates that the combination therapy of bevacizumab and dexamethasone implant given simultaneously is safe and synergistic resulting in significantly early and sustained visual recovery and decreased macular edema in patients having retinal vein occlusions. (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Scleral contact lenses for visual rehabilitation in keratoconus and irregular astigmatism after refractive surgery
This study aims to report our experience of using fluid-ventilated, gas-permeable scleral contact lenses (SCLs) for visual rehabilitation of patients with keratoconus and irregular astigmatism after refractive surgery. This is a noncomparative interventional case series reporting eight consecutive patients fitted with SCLs because of irregular astigmatism following the failure of other optical corrections. Retrospective chart review and data analysis included age, sex, etiology prior to lens fitting, visual outcomes, follow-up time, and complications. Twelve eyes of eight patients were studied. All eyes were fitted with SC...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Endocrinologic management of hyperthyroidism and the impact on thyroid eye disease
Publication date: June 2014 Source:Taiwan Journal of Ophthalmology, Volume 4, Issue 2 Author(s): Fatemeh Rajaii , Shivani Gupta , Raymond S. Douglas Thyroid eye disease (TED) is a complex inflammatory disease with a poorly understood etiopathogenesis. It is often, but not always, associated with Graves' disease and the endocrinologic manifestations of hyperthyroidism. Controversy exists regarding optimal treatment of hyperthyroidism especially with regard to the progression of orbitopathy. We review the literature examining the effectiveness of antithyroid drugs, radioactive iodine, and thyroidectomy for long-term e...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Vitreomacular interface diseases: Diagnosis and management
This article discusses the diagnosis and management of abnormal vitreomacular interfaces disorders including vitreomacular adhesion, vitreomacular traction, epiretinal membrane, full thickness macular holes, lamellar holes and pseudoholes. Optical coherence tomography has better enabled our ability to diagnose abnormalities of the vitreoretinal interface by providing clinical information that cannot be obtained by other ophthalmic diagnostic techniques. While vitrectomy remains the most commonly performed treatment for these disorders, the recent introduction of pharmacologic vitreolysis represents the development of non-s...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Ophthalmology in Taiwan
Publication date: June 2014 Source:Taiwan Journal of Ophthalmology, Volume 4, Issue 2 Author(s): Wen-Ming Hsu , Jorn-Hon Liu We herein report the current status of ophthalmology in Taiwan. There are 1667 ophthalmologists in Taiwan (up to the year 2011), with an average of 7.22 eye specialists/100,000 people. The ophthalmology residency program is a 4-year course in Taiwan, and around 40–44 new residents pass out each year. The Ophthalmological Society of Taiwan and many other professional ophthalmological organizations, and 30 teaching hospitals provide continuing education for practicing ophthalmologists and hospi...
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
Old dogs, new tricks: Modern scleral contact lenses in refractory corneal disease
Publication date: June 2014 Source:Taiwan Journal of Ophthalmology, Volume 4, Issue 2 Author(s): Yi-Yu Tsai (Source: Taiwan Journal of Ophthalmology)
Source: Taiwan Journal of Ophthalmology - November 7, 2014 Category: Opthalmology Source Type: research
