Delirium associated with concomitant use of duloxetine and bupropion in an elderly patient
Abstract Delirium is common in daily practice. Drug‐induced delirium constitutes approximately one‐third of all cases of delirium. In cases characterized by the limited efficacy of a single antidepressant, a combination of two antidepressants is required, which may induce a complex drug–drug interaction. We reviewed a case of duloxetine‐ and bupropion‐related delirium in an elderly male patient in our clinical practice. The patient was diagnosed with major depressive disorder and was treated with duloxetine. However, he developed delirium 10 days after bupropion was added to his treatment regimen. Three days afte...
Source: Psychogeriatrics - February 29, 2016 Category: Geriatrics Authors: Szu‐Pin Ma, Chia‐Jui Tsai, Cheng‐Chen Chang, Wen‐Yu Hsu Tags: Case Report Source Type: research

Evaluation of facilitative factors for preventing cognitive decline: A 3‐year cohort study of community intervention
ConclusionSubjects who had maintained a certain level of cognitive function, engaged in activities with friends, and went out frequently at baseline were extracted. In other words, the results suggested that enhancement of social networks and leisure activities prompted by recreational centre participation had a positive effect on maintaining cognitive function. The results also suggest that to improve the effectiveness of preventive interventions for cognitive dysfunction, support for social factors and leisure activities, in addition to cognitive function, may improve the long‐term effectiveness of maintaining cognitiv...
Source: Psychogeriatrics - February 8, 2016 Category: Geriatrics Authors: Daisuke Kimura, Tokunori Takeda, Tomoko Ohura, Aiko Imai Tags: Original Article Source Type: research

Evaluation of facilitative factors for preventing cognitive decline: A 3 ‐year cohort study of community intervention
ConclusionSubjects who had maintained a certain level of cognitive function, engaged in activities with friends, and went out frequently at baseline were extracted. In other words, the results suggested that enhancement of social networks and leisure activities prompted by recreational centre participation had a positive effect on maintaining cognitive function. The results also suggest that to improve the effectiveness of preventive interventions for cognitive dysfunction, support for social factors and leisure activities, in addition to cognitive function, may improve the long‐term effectiveness of maintaining cognitiv...
Source: Psychogeriatrics - February 7, 2016 Category: Geriatrics Authors: Daisuke Kimura, Tokunori Takeda, Tomoko Ohura, Aiko Imai Tags: Original Article Source Type: research

Behavioural effects of PNU‐282987 and stress in an animal model of Alzheimer's disease
ConclusionsFurther studies are needed in order to better understand the role of α7 nicotinic cholinergic receptor agonists in motor activity, anxiety, and spatial learning and memory and to develop more accurate pharmacological treatment of psychopathological diseases. (Source: Psychogeriatrics)
Source: Psychogeriatrics - January 27, 2016 Category: Geriatrics Authors: Paloma Vicens, Luis Heredia, Margarita Torrente, José L. Domingo Tags: Original Article Source Type: research

Patients who are not driving 6 weeks after transient ischaemic attack have higher levels of anxiety
(Source: Psychogeriatrics)
Source: Psychogeriatrics - January 27, 2016 Category: Geriatrics Authors: Simon M. Bell, Rejina Maniam, Alisha Patel, Kirsty Harkness, Daniel Blackburn Tags: Letter to the Editor Source Type: research