Beer effects on postprandial digestive symptoms and gastroesophagic physiology
Neurogastroenterology&Motility, EarlyView. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Source Type: research

The effect of a controlled gluten challenge in a group of patients with suspected non ‐coeliac gluten sensitivity: A randomized, double‐blind placebo‐controlled challenge
Neurogastroenterology&Motility, EarlyView. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Source Type: research

Anatomy and mechanical properties of the anal sphincter muscles in healthy senior volunteers
Neurogastroenterology&Motility, EarlyView. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Source Type: research

Impaired motility in Barrett's esophagus: A study using high ‐resolution manometry with physiologic challenge
Neurogastroenterology&Motility, EarlyView. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Source Type: research

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Neurogastroenterology&Motility, Ahead of Print. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Source Type: research

Impaired motility in Barrett's esophagus: A study using high ‐resolution manometry with physiologic challenge
Conclusions & InferencesReduced contractile effectiveness persisted in BE with the more representative esophageal challenge of swallowing solids and free drinking; while in ENRD and FHC peristalsis usually improved, demonstrating peristaltic reserve. Furthermore, symptom association and refluxate clearance were reduced in BE. These factors may underlie BE pathogenesis. Esophageal dysmotility is implicated in the pathogenesis of Barrett's esophagus, but has not been studied following solids and rapid drink challenge, which more accurately replicate normal swallowing behavior. With standard HRM using 5mL water swallows,...
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Authors: S. Sanagapalli, A. Emmanuel, R. Leong, S. Kerr, L. Lovat, R. Haidry, M. Banks, D. Graham, A. Raeburn, N. Zarate ‐Lopez, R. Sweis Tags: ORIGINAL ARTICLE Source Type: research

Anatomy and mechanical properties of the anal sphincter muscles in healthy senior volunteers
ConclusionsThis work reports baseline parameters describing the morpho‐mechanical condition of the sphincter muscle of healthy elderly volunteers. New parameters were also proposed to quantify the active properties of the muscles based on the mechanical energy associated with muscle contraction and fatigue. This information could be used to assess patients suffering from AI or for the design of novel implants. The mechanisms by which continence is maintained remain poorly understood. Therefore, we report a first statistical analysis of the involuntary (compliance) and voluntary (muscle work) mechanical properties of the...
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Authors: T. Brusa, D. Abler, R. Tutuian, C. Gingert, J. T. Heverhagen, M. Adamina, L. E. Br ügger, P. Büchler Tags: ORIGINAL ARTICLE Source Type: research

The effect of a controlled gluten challenge in a group of patients with suspected non ‐coeliac gluten sensitivity: A randomized, double‐blind placebo‐controlled challenge
Conclusions and InferencesThe present study showed that the majority of patients with suspected NCGS are not able to identify when challenged with gluten in a double‐blind placebo‐controlled food challenge, indicating that gluten is not the cause of their symptoms. The objective of this study was to characterize the response to an oral gluten‐challenge in patients with a symptom‐relief when following a gluten‐free diet. We found that the majority of patients with suspected NCGS are not able to identify when challenged with gluten in a DBPC gluten challenge, indicating that gluten is not the cause of their sympto...
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Authors: H. F. Dale, J. G. Hatlebakk, N. Hovdenak, S. O. Ystad, G. A. Lied Tags: ORIGINAL ARTICLE Source Type: research

Beer effects on postprandial digestive symptoms and gastroesophagic physiology
Conclusions and InferencesModerate consumption of traditional and alcohol‐free beer does not increase dyspeptic symptoms or GER in healthy subjects, whether in a controlled‐intake or real‐life situation. Neither gastric accommodation nor reflux episodes are modified in this context. Moderate consumption of traditional and alcohol‐free beer does not increase dyspeptic symptoms or GER in healthy subjects, whether in a controlled‐intake or real‐life situation. Neither gastric accommodation nor reflux episodes are modified in this context. (Source: Neurogastroenterology and Motility)
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Authors: B. Serrano Falc ón, M. Megía Sánchez, A. Ruiz de León, E. Rey Tags: ORIGINAL ARTICLE Source Type: research

Disruption of the pacemaker activity of interstitial cells of Cajal via nitric oxide contributes to postoperative ileus
Conclusions and InferencesThe generation and propagation of pacemaker potentials by ICC are disrupted via nitric oxide after IM, and this disruption may contribute to POI. When inflammation is ameliorated, ICC can recover their pacemaker function. The participation of interstitial cells of Cajal (ICC) in the postoperative ileus (POI) is not well understood. In a mouse model of POI, the propagation of electrical pacemaker activity and the networks of ICC were disrupted. These changes were mediated by nitric oxide. In addition to smooth muscle and enteric neuron, ICC may be a new therapeutic target cell for prevention and t...
Source: Neurogastroenterology and Motility - March 15, 2018 Category: Gastroenterology Authors: N. Kaji, S. Nakayama, K. Horiguchi, S. Iino, H. Ozaki, M. Hori Tags: ORIGINAL ARTICLE Source Type: research