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A pilot study with early adolescents: dealing with diet, tobacco and air pollution using practical experiences and biological markers
ConclusionsThe integrated approach, combined with the use of biological markers, could be an innovative approach to the promotion of healthy lifestyles among adolescents, but further research is needed. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - December 1, 2017 Category: Respiratory Medicine Source Type: research

Nasal Muco-ciliary transport time alteration: efficacy of 18 B Glycyrrhetinic acid
ConclusionsThis study shows the effectiveness of treatment with natural extracts with nasal mucosa restoring function in the treatment of chronic vasomotor rhinitis, a nasal inflammatory disease characterized by morphological and functional alteration of the normal nasal mucosa. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - November 29, 2017 Category: Respiratory Medicine Source Type: research

COPD management as a model for all chronic respiratory conditions: report of the 4 th Consensus Conference in Respiratory Medicine
AbstractBackgroundNon-communicable diseases (NCDs) kill 40 million people each year. The management of chronic respiratory NCDs such as chronic obstructive pulmonary disease (COPD) is particularly critical in Italy, where they are widespread and represent a heavy burden on healthcare resources. It is thus important to redefine the role and responsibility of respiratory specialists and their scientific societies, together with that of the whole healthcare system, in order to create a sustainable management of COPD, which could become a model for other chronic respiratory conditions.MethodsThese issues were divided into four...
Source: Multidisciplinary Respiratory Medicine - November 10, 2017 Category: Respiratory Medicine Source Type: research

Uneven distribution of professors and instructors in medical disciplines dealing with the four main chronic non-communicable diseases: the case of the Italian Universities
ConclusionsBoth national societies and ERS should promote periodic analyses of the academic situation of respiratory medicine in the European countries for advocating the EU in order to have recommendations/suggestions for the Member States to get the proper recognition of respiratory medicine, at the same level as the other disciplines involved in preventing and managing the four main NCD. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - November 2, 2017 Category: Respiratory Medicine Source Type: research

Case-finding for alpha1-antitrypsin deficiency in Kazakh patients with COPD
ConclusionThis study proved that AATD is present in the Kazakh population. These results support the general concept of targeted screening for AAT deficiency in countries like Kazakhstan, with a large population of COPD patients and low awareness among care-givers about this genetic condition. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - October 25, 2017 Category: Respiratory Medicine Source Type: research

Antibiotic therapy, supportive treatment and management of immunomodulation-inflammation response in community acquired pneumonia: review of recommendations
AbstractCommunity-acquired pneumonia is a common and serious disease, with high rates of morbidity and mortality. Management and treatment of community-acquired pneumonia are described in three main documents: the 2007 American Thoracic Society guidelines, the 2011 European Respiratory Society guidelines, and the 2009 British Thoracic Society guidelines, updated by the NICE in 2015. Despite the validity of current guidelines in improving prognosis and management of patients with community-acquired pneumonia, not all recommendations have high levels of evidence and there are still some controversial issues. In particular, t...
Source: Multidisciplinary Respiratory Medicine - October 5, 2017 Category: Respiratory Medicine Source Type: research

Second lung malignancy and Richter syndrome in chronic lymphocytic leukemia: case report and literature review
ConclusionsSteady surveillance of CLL patients and systematic screening for second solid tumors, particularly lung cancer, and Richter ’s transformation seem to be relevant more than ever. Early diagnosis might help us understand the pathways leading to these complications and adapt therapy. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - September 29, 2017 Category: Respiratory Medicine Source Type: research

Effects of combination therapy indacaterol/glycopyrronium versus tiotropium on moderate to severe COPD: evaluation of impulse oscillometry and exacerbation rate
ConclusionsThe “new” bronchodilator combination LABA/LAMA significantly reduces bronchial obstruction in small airways too. The oscillometry demonstrated greater sensitivity compared with spirometry for monitoring outcome measures of airway obstruction and the effect of long-term therapy. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - September 27, 2017 Category: Respiratory Medicine Source Type: research

Desmoplastic small round cell tumors of the pleura: a review of the clinical literature
AbstractDesmoplastic small round cell tumor of the pleura is a rare malignancy, with only a few cases reported in the scientific literature. The aim of the present review is to discuss the demographic, pathological, clinical, and therapeutic features of this rare tumor. English-language articles published since 1989, when the first case of desmoplastic small round cell tumor of the pleura was described, were retrieved, and fifteen cases included in fourteen articles were revised. The mean age of the patients was 25.5 years, out of them  60% were males. Chest pain, pleural effusion, and dyspnea were the most common clinica...
Source: Multidisciplinary Respiratory Medicine - September 9, 2017 Category: Respiratory Medicine Source Type: research

Could Eosinophilia predict clinical severity in nasal polyps?
ConclusionMucosal and peripheral eosinophilia can be used as a marker to predict disease severity in nasal polyps. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - August 21, 2017 Category: Respiratory Medicine Source Type: research

The history and epidemiology of Middle East respiratory syndrome corona virus
AbstractCorona viruses cause common cold, and infections caused by corona viruses are generally self-resolving. During the last 4  years, corona viruses have become the most important viruses worldwide because of the occurrence of several recent deaths caused by corona viruses in Saudi Arabia. Spread of the infection occurred worldwide; however, most cases of mortality have occurred in the Middle East. Owing to the predominan ce of outbreaks in the Middle Eastern countries, the virus was renamed a Middle East respiratory syndrome corona virus (MERS-CoV) by the Corona virus Study Group. The Center for Diseases Control and ...
Source: Multidisciplinary Respiratory Medicine - August 7, 2017 Category: Respiratory Medicine Source Type: research

Implementation of GOLD consensus report in real life: results from the Velletri-Lariano (VELA) cohort
ConclusionsThese results describe for the first time the distribution of COPD patients in an Italian cohort according to the GOLD categories, with the highest frequencies in levels B and D. The misclassification from HCPs may impact the therapeutic approach and the clinical outcomes. (Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - July 17, 2017 Category: Respiratory Medicine Source Type: research

Novel aspects in diagnostic approach to respiratory patients: is it the time for a new semiotics?
AbstractMedical approach to patients is a fundamental step to get the correct diagnosis. The aim of this paper is to analyze some aspects of the reasoning process inherent in medical diagnosis in our era. Pathologic signs (anamnestic data, symptoms, semiotics, laboratory and strumental findings) represent informative phenomena to be integrated for inferring a diagnosis. Thus, diagnosis begins with “signs” and finishes in a probability of disease. The abductive reasoning process is the generation of a hypothesis to explain one or more observations (signs) in order to decide between alternative explanations searching the...
Source: Multidisciplinary Respiratory Medicine - June 27, 2017 Category: Respiratory Medicine Source Type: research

Erratum to: Recent advances in capsule-based dry powder inhaler technology
(Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - June 23, 2017 Category: Respiratory Medicine Source Type: research

Erratum to: The evidence on tiotropium bromide in asthma: from the rationale to the bedside
(Source: Multidisciplinary Respiratory Medicine)
Source: Multidisciplinary Respiratory Medicine - June 1, 2017 Category: Respiratory Medicine Source Type: research