Multi-atlas pancreas segmentation: Atlas selection based on vessel structure
Automated abdominal organ segmentation from three-dimensional medical images is one of the essential components for clinical applications, such as computer-aided diagnosis (CAD) (Kobatake, 2007), computer-assisted surgery (CAS) planning and navigation (Azagury et  al., 2012). Pancreatic cancer has recently been increasing globally (Ito et al., 2013), and its mortality rate is the fourth among cancer-related deaths in Japan, 2011 (Matsuda et al., 2011). Because pancreatic cancer is difficult to treat and has such a high mortality rate, it would be benefici al to develop systems to automatically detect the pancreatic regi...
Source: Medical Image Analysis - March 30, 2017 Category: Radiology Authors: Ken ’ichi Karasawa, Masahiro Oda, Takayuki Kitasaka, Kazunari Misawa, Michitaka Fujiwara, Chengwen Chu, Guoyan Zheng, Daniel Rueckert, Kensaku Mori Source Type: research

Semi-Local Tractography Strategies Using Neighborhood Information
Emerging in the mid-1980s (Le  Bihan and Breton, 1985; Merboldt et al., 1985; Taylor and Bushell, 1985), Diffusion MRI is an imaging modality that has since been widely used for measuring the movement of water molecules in biological tissue in vivo. In fibrous tissue, for instance in human brain white matter, diffusion is know n to be fastest parallel to fibers but highly restrained perpendicular to the fiber orientation (Beaulieu, 2002). Thus, information about nerve fiber bundle orientation in the living human brain can be inferred from Diffusion MRI data noninvasively. (Source: Medical Image Analysis)
Source: Medical Image Analysis - March 24, 2017 Category: Radiology Authors: Helen Schomburg, Thorsten Hohage Source Type: research

Transformation Diffusion Reconstruction of Three-Dimensional Histology Volumes from Two-Dimensional Image Stacks
Traditional histology, the study of tissue microarchitecture, originated in the 17th c. with first applications of microscopy to animal-derived samples by Marcello Malpighi. It has become the gold standard for structural description of cells and tissue, serving important functions in clinical diagnosis of pathologies. Traditional histology produces two-dimensional (2D) images, resolving cellular and sub-cellular detail in slices that typically are several micrometers thick. A wide variety of chromatic stains, developed since the 18th c., enable cell labelling (e.g. (Source: Medical Image Analysis)
Source: Medical Image Analysis - March 22, 2017 Category: Radiology Authors: Ram ón Casero, Urszula Siedlecka, Matthew Gibb, Jürgen E. Schneider, Peter Kohl, Vicente Grau Source Type: research

Robust Guidewire Tracking under Large Deformations Combining Segment-Like Features (SEGlets)
Robust tracking of interventional tools, such as guidewires and catheters, in X-ray fluoroscopic video sequences has a wide range of clinical applications for endovascular procedures. Thus far, the tracking is usually achieved by finding the optimal displacement of the control points of a spline, which models the guidewire, between consecutive frames. The displacement of the control points is typically driven by a data term and smoothed by a regularization term. In the presence of large deformation and changes in length of the tool, the current tracking methods may fail to recover the guidewire motion. (Source: Medical Image Analysis)
Source: Medical Image Analysis - March 15, 2017 Category: Radiology Authors: Alessandro Vandini, Ben Glocker, Mohamad Hamady, Guang-Zhong Yang Source Type: research

Population model of bladder motion and deformation based on dominant eigenmodes and mixed-effects models in prostate cancer radiotherapy
Prostate cancer is one the most common cancer types worldwide. One of the standard treatment methods is external radiotherapy, which involves delivering ionizing radiation to a clinical target, namely the prostate and seminal vesicles. Due to the uncertain location of organs during treatment, consisting around 40 radiation fractions delivering a total dose ranging from 70 to 80Gy, safety margins are defined around the tumor target upon treatment planning. This also leads to portions of healthy organs neighboring the prostate or organs at risk – the bladder and rectum – to be included in the target volume, potentially r...
Source: Medical Image Analysis - March 7, 2017 Category: Radiology Authors: Richard Rios, Renaud De Crevoisier, Juan D. Ospina, Frederic Commandeur, Caroline Lafond, Antoine Simon, Pascal Haigron, Jairo Espinosa, Oscar Acosta Source Type: research