[Perspectives] Illuminating the body
This instalment of the Scottish National Gallery of Modern Art's NOW series brings together the work of artists who explore ideas related to the human body, performance, process, and materials. The highlight of the show is a selection of works by Jenny Saville. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Fiona Mitchell Tags: Perspectives Source Type: research

[Perspectives] Plastic perfection
At a time of increasing dissatisfaction with the natural body, people are ever more likely to call for the sculptor with the scalpel. Two-thirds of young people and adults in the UK are unhappy about how they look, and cosmetic surgery is big business. British artist Jonathan Yeo's new exhibition shows his long-held interest in ideas of bodily perfection and their shaping by new technologies. Self-taught as a portraitist while recovering from Hodgkin's lymphoma as a young man, Yeo achieved fame with paintings of celebrities such as Damien Hirst, Nicole Kidman, and Dennis Hopper. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Charles Fernyhough Tags: Perspectives Source Type: research

[World Report] Pimavanserin evaluated by the FDA
The US Food and Drug Administration is conducting an evaluation of available evidence about pimavanserin. Paul Webster reports. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Paul Webster Tags: World Report Source Type: research

[World Report] Managing MDR tuberculosis in Nepal
The burden of multidrug and extensively drug resistant tuberculosis might be underevaluated among Nepalis, threatening bordering countries. Sophie Cousins reports from Kathmandu. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Sophie Cousins Tags: World Report Source Type: research

[World Report] El Salvador's total ban on abortion risks women's health
The total and enforceable ban on abortion creates a climate of fear among medical professionals and threatens women's health. Amanda Sperber reports from San Salvador. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Amanda Sperber Tags: World Report Source Type: research

[Comment] Offline: A Caribbean consciousness
The word Windrush now defines the shame of a nation, a nation that once courted, welcomed, and put to work Caribbean migrants to fill shortages in Britain's labour market after World War 2. The cold expediency of modern British politics, the racist nationalism of today's England, and the angry isolationism of Brexiteers have combined to foster a bitterly hostile environment for anyone with a skin colour or accent deemed outside populist boundaries of acceptability. The British colonialist state expropriated riches from those it occupied to build an inglorious Empire. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Richard Horton Tags: Comment Source Type: research

[Comment] The gendered system of academic publishing
Gender is a sociocultural and economic concept and an institutionalised system of social practices that translates into different experiences and uneven advantages for men and women at the individual, organisational, and societal levels.1 This system manifests as the persistent gender pay gap, endemic sexual harassment,2 and the proverbial glass ceiling limiting women's representation and advancement in social and economic life. Academia, including academic publishing, is not immune to this gendered system of social practices. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Jamie Lundine, Ivy Lynn Bourgeault, Jocalyn Clark, Shirin Heidari, Dina Balabanova Tags: Comment Source Type: research

[Comment] Who is responsible for the vaccination of migrants in Europe?
A report from WHO exploring the provision of immunisation services to migrants and refugees in the WHO European Region1 provides a stark reminder that European health services are a long way off adapting to the rapid demographic shift that the region has witnessed in the past two decades, amid unprecedented rises in internal and external migration. Migrants are more likely to be under-immunised —putting them at increased risk of vaccine-preventable diseases circulating in Europe—and may face greater disease, disability, and deaths from vaccine-preventable diseases than the host population. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Sally Hargreaves, Laura B Nellums, Mary Ramsay, Vanessa Saliba, Azeem Majeed, Sandra Mounier-Jack, Jon S Friedland Tags: Comment Source Type: research

[Editorial] Austerity in Spain: time to loosen the grip
Calculating the health impact of a financial crisis and subsequent austerity measures is an inexact science. A new UN report, published on April 25, 2018, illuminates the repercussions on health care of the 2008 monetary crisis, state retrenchment, and the implementation of a royal decree in Spain, echoing findings of an earlier European Commission 2017 Country Health Profile. The consequences and patient perceptions of Spain's emergency rescue package in the wake of the financial crash were also analysed in an Amnesty International document, published April 24, 2018. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: The Lancet Tags: Editorial Source Type: research

[Editorial] Progress in the USA for autistic spectrum disorder
The prevalence of autistic spectrum disorder is increasing in the USA, the latest figures from the Centers for Disease Control and Prevention suggest. According to the Autism and Developmental Disabilities Monitoring Network (ADDM), the prevalence of autistic spectrum disorder in children was 16 ·8 per 1000 in 2014—an absolute increase of 2·2% since 2012 and more than double the prevalence in 2000 when monitoring by the ADDM began. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: The Lancet Tags: Editorial Source Type: research

[Editorial] Campaigning for preconception health
A three-paper Series on preconception health in this week's issue draws special attention to an underappreciated period in the lifecycle with far-reaching consequences across the lifecourse. The Series highlights the importance of good health and nutrition of both women and men before conception, not only for the ability to conceive, pregnancy outcomes, and maternal and child health immediately after birth but also for the long-term health of the next generation and beyond. While it is now widely accepted that alcohol, smoking, certain medications, caffeine, and poor nutritional status during pregnancy have adverse outcome...
Source: LANCET - May 4, 2018 Category: General Medicine Authors: The Lancet Tags: Editorial Source Type: research

[Articles] Cardiovascular disease risk prediction equations in 400  000 primary care patients in New Zealand: a derivation and validation study
We constructed a large prospective cohort study representing typical patients in primary care in New Zealand who were recommended for cardiovascular disease risk assessment. Most patients are now at low risk of cardiovascular disease, which explains why the PCEs based mainly on old cohorts substantially overestimate risk. Although the PCEs and many other equations will need to be recalibrated to mitigate overtreatment of the healthy majority, they also need new predictors that include measures of socioeconomic deprivation and multiple ethnicities to identify vulnerable high-risk subpopulations that might otherwise be under...
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Romana Pylypchuk, Sue Wells, Andrew Kerr, Katrina Poppe, Tania Riddell, Matire Harwood, Dan Exeter, Suneela Mehta, Corina Grey, Billy P Wu, Patricia Metcalf, Jim Warren, Jeff Harrison, Roger Marshall, Rod Jackson Tags: Articles Source Type: research

[Comment] Contemporary cardiovascular risk prediction
Cardiovascular disease remains an important health problem, accounting for 3 ·9 million deaths every year in Europe alone.1 To reduce the incidence of cardiovascular disease, risk prediction models are widely used for risk-tailored management, such as antihypertensive and lipid-lowering treatment. More than 350 risk prediction models have been developed for cardiovascular d isease in the past decades. These models are mainly based on long-standing cohort data, but only a few models have been validated externally to test their generalisability in present settings. (Source: LANCET)
Source: LANCET - May 4, 2018 Category: General Medicine Authors: Johanna A A G Damen, Lotty Hooft, Karel G M Moons Tags: Comment Source Type: research

[Comment] New leadership for the WHO Regional Office for the Eastern Mediterranean: exceptional election in an exceptional time
On May 19, 2018, during the 71st World Health Assembly, the 21 health ministers, or their representatives, from the Eastern Mediterranean region are due to elect a new Regional Director for the WHO Regional Office for the Eastern Mediterranean (EMRO) in a special session of its regional committee. The exceptional election follows the unexpected death of Mahmoud Fikri who was WHO EMRO Regional Director for only 8 months during 2017. WHO has accelerated the normally lengthy election process to fill the vacuum in WHO EMRO leadership. (Source: LANCET)
Source: LANCET - May 2, 2018 Category: General Medicine Authors: Samer Jabbour, Sameen Siddiqi, Rita Giacaman, Hani Serag, Jawad Al-Lawati, Amirhossein Takian, Habiba Ben Romdhane, Elsheikh Badr, Laith J Abu-Raddad, Aida Seif El-Dawla, Salwa Najjab, Driss Moussaoui, Mustafa Khogali, Yousef Khader, Bothaina Attal, Iman Tags: Comment Source Type: research

[Articles] Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis
In acutely ill adults, high-quality evidence shows that liberal oxygen therapy increases mortality without improving other patient-important outcomes. Supplemental oxygen might become unfavourable above an SpO2 range of 94 –96%. These results support the conservative administration of oxygen therapy. (Source: LANCET)
Source: LANCET - April 27, 2018 Category: General Medicine Authors: Derek K Chu, Lisa H-Y Kim, Paul J Young, Nima Zamiri, Saleh A Almenawer, Roman Jaeschke, Wojciech Szczeklik, Holger J Sch ünemann, John D Neary, Waleed Alhazzani Tags: Articles Source Type: research