Calciphylaxis – A case study in a patient with Maori heritage
This case history describes a rare complaint – Calciphylaxis, seen in a New Zealand Maori patient undergoing renal dialysis. This condition causes non-healing tissue ulceration, typically with sepsis and is associated with a very high mortality rate. The need for vigilance among health professionals is highlighted, including the risk factors that may faciliate an early diagnosis; together with the value associated with a multi-disciplinary team approach to management. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - July 4, 2016 Category: Internal Medicine Authors: Lawrence Kingi, Roger Grech, Michael Lam, Ajith Dissanayake, Simon Otter Tags: Case report Source Type: research

Calciphylaxis – a case study in a patient with Maori heritage
This case history describes a rare complaint – Calciphylaxis, seen in a New Zealand Maori patient undergoing renal dialysis. This condition causes non-healing tissue ulceration, typically with sepsis and is associated with a very high mortality rate. The need for vigilance among health professionals is highlighted, including the risk factors that may faciliate an early diagnosis; together with the value associated with a multi-disciplinary team approach to management. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - July 4, 2016 Category: Internal Medicine Authors: Lawrence Kingi, Roger Grech, Michael Lam, Ajith Dissanayake, Simon Otter Tags: Case report Source Type: research

Effectiveness of basic fibroblast growth factor for pediatric hand burns
Pediatric hand deep dermal and deep burns may lead to serious hand deformity with functional impairment and result in an esthetically unfavorable outcome. Since there is no guideline regarding the use of growth factors for pediatric hand burns, we sought to investigate the effectiveness of an angiogenic and regenerative growth factor, basic fibroblast growth factor (bFGF). (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 27, 2016 Category: Internal Medicine Authors: Kenji Hayashida, Masaki Fujioka, Shin Morooka, Hiroto Saijo, Sadanori Akita Source Type: research

Corrigendum to “Editorial” [J. Tissue Viability 25 (2016) 1–2]
The authors regret for omitting in the references of the two reports detailed in the editorial published in Journal of Tissue Viability. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 25, 2016 Category: Internal Medicine Tags: Corrigendum Source Type: research

Calendar of Events
September 2016 (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 25, 2016 Category: Internal Medicine Source Type: research

Genetic and molecular basis of diabetic foot ulcers: Clinical review
Diabetic Foot Ulcers (DFUs) are major complications associated with diabetes and often correlate with peripheral neuropathy, trauma and peripheral vascular disease. It is necessary to understand the molecular and genetic basis of diabetic foot ulcers in order to tailor patient centred care towards particular patient groups. This review aimed to evaluate whether current literature was indicative of an underlying molecular and genetic basis for DFUs and to discuss clinical applications. From a molecular perspective, wound healing is a process that transpires following breach of the skin barrier and is usually mediated by gro...
Source: Journal of Tissue Viability - June 24, 2016 Category: Internal Medicine Authors: Shaurya Jhamb, Venkat N. Vangaveti, Usman H. Malabu Source Type: research

Lacking the ‘protective label’ of diabetes: Phenytoin-induced distal symmetrical peripheral neuropathy. A clinical case report
This report documents an unusual case of distal symmetrical peripheral neuropathy (DSPN) in an otherwise healthy patient without diabetes mellitus (DM) presenting to a podiatric wound care clinic. The development of gas gangrene coupled with Charcot neuroarthropathic changes ultimately resulted in a potentially life-saving transmetatarsal (TMT) amputation. Causation of, or at least a contributor to, the DSPN was likely phenytoin usage for epileptic seizures. Long-term use of phenytoin can lead to axonal shrinkage and random clusters of nerve demyelination [1]. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 23, 2016 Category: Internal Medicine Authors: A.M. Mahon Tags: Case report Source Type: research

Rotational repair of pressure ulcer using double-perforators based flaps: A report of 11 cases
National Pressure Ulcer Advisory Panel (NPUAP) stage 3 and 4 pressure ulcers typically require surgical repair with perforator-based flaps and fasciocutaneous flaps. We designed advancement/rotation flaps based on two different perforators originating from two different mother vessels that covered large pressure ulcers without the need for additional skin grafts for donor sites. In this paper, we describe the surgical technique on the use of the advancement/rotation flaps and report the preliminary results of surgical management of 11 cases of pressure ulcers using advancement/rotation flaps. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 14, 2016 Category: Internal Medicine Authors: Nan Zhang, Xin Yu, Qiuyan Zhao, Kai Shi, Zhenghua Jin, Xi Zhang, Hong Lei, Jiaao Yu Tags: Case report Source Type: research

Induction of delayed wound healing by irradiation with optional mechanical compression in swine
This study was designed to create delayed wound healing induced by irradiation and mechanical compression using silicone block. Two female pigs received a single fraction of 20  Gy with 6-MeV electrons to a 22 × 60 cm field on the dorsal body skin 7 weeks before experimentation. A 30 × 30 mm sized wounds were created with preservation of muscle fascia on the dorsum. In groups of six, wounds were designated to be control (C) or test areas of irradiation only (T0), irradiation with silicone blocks for 1 week (T1), irradiation with silicone blocks for 2 weeks (T2), and irradiation with silicone blocks for 3 weeks (T3...
Source: Journal of Tissue Viability - June 14, 2016 Category: Internal Medicine Authors: Woonhyeok Jeong, Daemyung Oh, Sunyoung Kwon, Jinhee Kim, Daegu Son Source Type: research

Rotational repair of pressure ulcer using double-perforators based flaps: A report of 11 cases
National Pressure Ulcer Advisory Panel (NPUAP) stage 3 and 4 pressure ulcers typically require surgical repair with perforator-based flaps and fasciocutaneous flaps. We designed advancement/rotation flaps based on two different perforators originating from two different mother vessels that covered large pressure ulcers without the need for additional skin grafts for donor sites. In this paper, we describe the surgical technique on the use of the advancement/rotation flaps and report the preliminary results of surgical management of 11 cases of pressure ulcers using advancement/rotation flaps. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 14, 2016 Category: Internal Medicine Authors: Nan Zhang, Xin Yu, Qiuyan Zhao, Kai Shi, Zhenghua Jin, Xi Zhang, Hong Lei, Jiaao Yu Tags: Case report Source Type: research

Induction of delayed wound healing by irradiation with optional mechanical compression in swine
This study was designed to create delayed wound healing induced by irradiation and mechanical compression using silicone block. Two female pigs received a single fraction of 20 Gy with 6-MeV electrons to a 22 × 60 cm field on the dorsal body skin 7 weeks before experimentation. A 30 × 30 mm sized wounds were created with preservation of muscle fascia on the dorsum. In groups of six, wounds were designated to be control (C) or test areas of irradiation only (T0), irradiation with silicone blocks for 1 week (T1), irradiation with silicone blocks for 2 weeks (T2), and irradiation with silicone blocks for 3 weeks (T3)...
Source: Journal of Tissue Viability - June 14, 2016 Category: Internal Medicine Authors: Woonhyeok Jeong, Daemyung Oh, Sunyoung Kwon, Jinhee Kim, Daegu Son Source Type: research