Calendar of Events
2017 (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 30, 2017 Category: Internal Medicine Source Type: research

Personalized modeling for real-time pressure ulcer prevention in sitting posture
Ischial pressure ulcer is an important risk for every paraplegic person and a major public health issue. Pressure ulcers appear following excessive compression of buttock's soft tissues by bony structures, and particularly in ischial and sacral bones. Current prevention techniques are mainly based on daily skin inspection to spot red patches or injuries. Nevertheless, most pressure ulcers occur internally and are difficult to detect early. Estimating internal strains within soft tissues could help to evaluate the risk of pressure ulcer. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 14, 2017 Category: Internal Medicine Authors: Vincent Luboz, Mathieu Bailet, Christelle Boichon Grivot, Michel Rochette, Bruno Diot, Marek Bucki, Yohan Payan Source Type: research

Platelet-rich plasma with keratinocytes and fibroblasts enhance healing of full-thickness wounds
In this study, we determine the possibility of using a low density of human skin cells suspended in platelet-rich plasma (PRP)-enriched medium to promote the healing of full-thickness skin wounds. To achieve this, full-thickness wounds of size 1.767  cm2 were created at the dorsum part of nude mice and treated with keratinocytes (2 × 104 cells/cm2) and fibroblasts (3 × 104 cells/cm2) suspended in 10% PRP-enriched medium. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 7, 2017 Category: Internal Medicine Authors: Jia Xian Law, Shiplu Roy Chowdhury, Aminuddin Bin Saim, Ruszymah Bt Hj Idrus Source Type: research

Mesenchymal stem cell in venous leg ulcer: An intoxicating therapy
Venous leg ulcers (VLU) are a prevalent and reoccurring type of complicated wound, turning as a considerable public healthcare issue, with critical social and economic concern. There are both medical and surgical therapies to treat venous leg ulcers; however, a cure does not yet exist. Mesenchymal stem cells (MSC) are capable and proved of accelerating wound healing in vivo and their study with human chronic wounds is currently awaited. MSCs are a promising source of adult progenitor cells for cellular therapy and have been demonstrated to differentiate into various mesenchymal cell lineages. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - June 6, 2017 Category: Internal Medicine Authors: Anjali Athanerey, Pradeep Kumar Patra, Awanish Kumar Source Type: research

Off loading wheelchair cushion provides best case reduction in tissue deformation as indicated by MRI
Off-loading or the Orthotic approach to wheelchair seating has been used successfully to provide seating that optimizes tissue protection at the ischial tuberosities (ITs), sacrum and greater trochanters. Recent publications indicate the significance of preventing tissue compression to reduce ulcer formation. Comparative Magnetic Resonance Imaging (MRI) of individuals seated on two cushion types provides direct evidence of tissue unloading resulting in the reduction in tissue compression. Measurement of tissue compression in MRI images provides the cumulative impact of compression and shear resulting in ultimate tissue thi...
Source: Journal of Tissue Viability - May 17, 2017 Category: Internal Medicine Authors: Evan Call, Thomas Hetzel, Chad McLean, Joshua N. Burton, Craig Oberg Source Type: research

Pressure signatures can influence tissue response for individuals supported on an alternating pressure mattress
Prolonged mechanical loading can lead to the breakdown of skin and underlying tissues which can, in turn, develop into a pressure ulcer. The benefits of pressure relief and/or redistribution to minimise risk have been well documented. Manufacturers have developed alternating air pressure mattresses (APAMs) to provide periodic relief for individuals on prolonged bed-rest. The present study describes the development of a control system, termed Pneumatic Manager which can vary the signature of an APAM, namely its pressure amplitude, cell profile and cycle period. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - May 10, 2017 Category: Internal Medicine Authors: C.Y. Chai, O. Sadou, P.R. Worsley, D.L. Bader Source Type: research

Calendar of Events
2017 (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - May 1, 2017 Category: Internal Medicine Source Type: research

Beware of the toilet: The risk for a deep tissue injury during toilet sitting
A pressure injury (PrI) compromises quality of life and can be life-threatening. The fundamental cause of PrIs is sustained deformations in weight-bearing soft tissues, e.g., during prolonged sitting on inadequate surfaces such as a toilet seat. In nursing homes and geriatric facilities, patients need assistance using the restroom, and patients being left on the toilet for tens-of-minutes is a real-world scenario, unfortunately. Nevertheless, there are no published studies regarding sustained tissue loads during toilet sitting and their effects on tissue physiology. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 22, 2017 Category: Internal Medicine Authors: Maayan Lustig, Ayelet Levy, Kara Kopplin, Zehava Ovadia-Blechman, Amit Gefen Source Type: research

A pilot study comparing custom contoured and planar support surfaces for pressure ulcer risk over the heels for night time postural management using interface pressure mapping and discomfort scores
Custom contouring techniques are effective for reducing pressure ulcer risk in wheelchair seating. These techniques may assist the management of pressure ulcer risk during sleep for night time postural management. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 21, 2017 Category: Internal Medicine Authors: J. Hosking Source Type: research

Healing potential of zerumbone ointment on experimental full-thickness excision cutaneous wounds in rat
Zerumbone is a monocyclic sesquiterpene compound. Based on report, it is the predominant bioactive compound from the rhizomes of Zingiber zerumbet. The study was undertaken to evaluate the therapeutic effects of topical zerumbone on excision wounds in rats. A 1% (w/w) simple ointment containing zerumbone was applied topically (100  mg ointment per rat) once a day on full-thickness excision wounds created on rats. The wound tissue was removed and used for estimation of antioxidant activity and to observe histopathological changes. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 15, 2017 Category: Internal Medicine Authors: Wayne Young Liu, Thing-Fong Tzeng, I-Min Liu Source Type: research

The effect of pressure and shear on tissue viability of human skin in relation to the development of pressure ulcers: A systematic review
Pressure ulcers are a significant problem in health care, due to high costs and large impact on patients' life. In general, pressure ulcers develop as tissue viability decreases due to prolonged mechanical loading. The relation between load and tissue viability is highly influenced by individual characteristics. It is proposed that measurements of skin blood flow regulation could provide good assessment of the risk for pressure ulcer development, as skin blood flow is essential for tissue viability. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 14, 2017 Category: Internal Medicine Authors: Iris Hoogendoorn, Jasper Reenalda, Bart F.J.M. Koopman, Johan S. Rietman Source Type: research

An MRI investigation of the effects of user anatomy and wheelchair cushion type on tissue deformation
This study investigated the effects of anatomy and wheelchair cushion type on tissue deformation. (Source: Journal of Tissue Viability)
Source: Journal of Tissue Viability - April 11, 2017 Category: Internal Medicine Authors: David Brienza, Jaxon Vallely, Patricia Karg, Jonathan Akins, Amit Gefen Source Type: research