Simulation of the Effect of Different Presbyopia-Correcting Intraocular Lenses With Eyes With Previous Laser Refractive Surgery
It has been demonstrated that higher order aberrations (HOAs) increase after laser refractive surgery.1 –4 The most commonly affected aberration is the spherical aberration, which increases positively after myopic laser surgery and negatively after laser correction for hyperopia.1–4 It is crucial to know the type of aberrations induced by currently available presbyopia-correcting IOLs for evaluati ng whether their implantation is recommendable in eyes with previous laser refractive surgery that are already aberrated. From a clinical perspective, the outcomes of the implantation of (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - April 11, 2018 Category: Opthalmology Authors: Vicente J. Camps, PhD Source Type: research
Erratum for “Analysis of Accommodative Performance of a New Accommodative Intraocular Lens”
The article “Analysis of Accommodative Performance of a New Accommodative Intraocular Lens” by Alió et al., which was published in the February 2018 issue of the Journal of Refractive Surgery (volume 34, number 2, pp. 78–83), has been amended to include a factual correction. An error was identified subse quent to its original printing. The captions for Figures 1–2 were incorrect. The figure captions should read: “Figure 1. Mean defocus curves of the accommodative (blue), monofocal (red), and control (green) groups. D = diopters” and “Figure 2. Mean objective accommodation with the (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: TBD Source Type: research
The Sensitivity of Clinical Outcomes to Centration on the Light-Constricted Pupil for a Shape-Changing Corneal Inlay
Centration of corneal refractive procedures currently has only two pragmatic reference locations: the coaxially sighted corneal light reflex (CSCLR) or the pupil center. If the camera capturing the pupil image is coaxial with the patient's fixation point, the CSCLR is a good approximation of the point on the cornea containing the theoretical concept of a “visual axis.”1,2 For non–wavefront-guided LASIK and photorefractive keratectomy, centration of the ablation pattern on or close to the CSCLR is currently believed to optimize refractive outcomes and minimize induction of higher order (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Enrique Barrag án-Garza, MD Source Type: research
Evaluation of the Accuracy of Two Marking Methods and the Novel toriCAM Application for Toric Intraocular Lens Alignment
It has been shown that approximately 30% of patients undergoing cataract surgery have corneal astigmatism of more than 0.75 diopters (D).1 Postoperative residual astigmatism decreases unaided visual acuity and quality of vision.2 A better understanding of the effect of posterior corneal astigmatism3 and the availability of more accurate toric intraocular lens (IOL) predictions have improved the ability to correct astigmatism with toric IOLs during cataract surgery, even in patients with low preexisting cylinder.4 Toric IOLs need to be positioned accurately on the intended meridian to have (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Andreas Pallas, MD Source Type: research
Should the Corvis Biomechanical Index (CBI) Include Corneal Thickness Parameters?
We read with great interest the article by Steinberg et al.1 regarding a modified Corvis Biomechanical Index (named aCBI in the article) with the elimination of corneal thickness data, including the Ambr ósio's Relational Thickness in the horizontal profile (ARTh). The aim of the cited article was to provide a proof of concept of whether corneal deformation (biomechanics) alone would be sufficient to separate normal patients from patients with keratoconus.1 This was accomplished by creating the aCB I algorithm without the ARTh in a pairwise matching of normal and keratoconic eyes with regard to (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Riccardo Vinciguerra, MD Source Type: research
Predictability of Tunnel Depth for Intrastromal Corneal Ring Segments Implantation Between Manual and Femtosecond Laser Techniques
Intrastromal corneal ring segments (ICRS) implantation is a surgical procedure used for the treatment of keratoconus, enabling both a therapeutic and refractive improvement.1 –3 Both the safety and the refractive efficacy of the implant depend on the correct selection of the implant features and a precise intrastromal surgical implantation. Shallower intrastromal tunnels are associated with complications such as implant exposure due to corneal thinning over the implant , segment migration and extrusion, astigmatism overcorrection, or corneal melting.4–6 Deeper tunnels can be associated with (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Tiago Monteiro, MD, FEBO Source Type: research
Clinical Outcomes of SMILE With a Triple Centration Technique and Corneal Wavefront-Guided Transepithelial PRK in High Astigmatism
Small incision lenticule extraction (SMILE) is a femtosecond laser –based technique for the correction of myopic errors.1–4 It has become popular in the field of refractive surgery since Shah et al.5 and Sekundo et al.6 first reported the clinical outcomes of SMILE in 2011. SMILE provides faster recovery and a lower risk of haze than photorefractive keratectomy (PRK).7 In contrast, relative to LASIK, corneas treated by SMILE might remain more resistant and exhibit a lesser decrease in corneal sensitivity.7,8 Single-step transepithelial PRK, which involves the removal of epithelium by laser (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Ikhyun Jun, MD, PhD Source Type: research
Histological and microRNA Signatures of Corneal Epithelium in Keratoconus
Keratoconus is a corneal ectatic disorder characterized by irregular astigmatism and mild to severe visual impairment. As the disease advances, approximately 20% of the patients require keratoplasty for visual rehabilitation.1,2 The etiology of keratoconus is complex and multifactorial, involving both genetic and environmental factors. Our previous genome-wide association study identified 26 loci associated with central corneal thickness, among which FOXO1 and FNDC3B confer high risk for keratoconus.2 Another exome sequencing analysis also reported the association of a WNT10A variant with (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Yu Meng Wang, MMed Source Type: research
Effect of Conus Eccentricity on Visual Outcomes After Intracorneal Ring Segments Implantation in Keratoconus
Intracorneal ring segments (ICRS) are small polymethylmethacrylate devices implanted into the cornea to alter its geometry in a manner that will enhance its refractive properties and thereby improve visual acuity. The concept of ICRS implantation was first proposed by Burris1 in 1978 for treatment of myopia. Colin et al.2 introduced the use of ICRS implantation for the management of keratoconus in 2000. Since then, many different types of ICRS with variable thickness, geometry, and diameter have been developed and used for restoring visual acuity in patients with keratoconus. Their (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Zisis Gatzioufas, MD, PhD Source Type: research
The 7-Year Outcomes of Epithelium-Off Corneal Cross-linking in Progressive Keratoconus
Corneal cross-linking (CXL) with riboflavin and ultraviolet-A (UVA) 370-nm radiation is capable of arresting the progression of keratoconus, with significant improvements in visual, keratometric, and topo-graphic measurements.1 However, most studies report clinical improvements and stability in a short- or medium-term follow-up,2 –9 with few studies reporting the real capability of CXL for maintaining the corneal shape and structure in the long term.10 Raiskup et al.10 reported the outcomes in terms of visual acuity, refraction, corneal curvature, and endothelial cell count changes 10 years (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Mohamed Shafik Shaheen, MD, PhD Source Type: research
Progression of Keratoconus in Patients While Awaiting Corneal Cross-linking: A Prospective Clinical Study
Keratoconus is the most common progressive ectatic corneal disease.1 Although keratoconus is the second most common indication for corneal transplantation worldwide,2 the introduction of corneal cross-linking (CXL) has led to a reduction in the number of patients requiring a corneal transplant.3,4 Developments in corneal topography and tomography have enabled the detection of keratoconus at an early stage.5 The rate and speed of the progression of keratoconus has been reported to be higher in children6,7 and, as a result, patients with an earlier onset may be more likely to require subsequent (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Vito Romano, MD Source Type: research
Nepafenac Ophthalmic Suspension 0.3% for the Management of Ocular Pain After Photorefractive Keratectomy
Management of postoperative ocular pain after photorefractive keratectomy (PRK) has been a significant goal of refractive surgery to render PRK a more popular procedure. Use of contact lenses postoperatively has improved pain management but remains insufficient for some patients. Pharmaceutical treatments such as topical anesthetics and topical anti-inflammatory agents targeting the molecular mediators of pain have been effective in reducing postoperative discomfort. Topical anesthetics are effective in reducing pain but have a limited use due to the risk of anesthetic abuse keratopathy. (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: George A. Kontadakis, MD, PhD Source Type: research
Corneal Cross-linking Standardized Terminology
We read with interest the editorial entitled “Corneal Cross-linking (CXL): Standardizing Terminology and Protocol Nomenclature.”1 We would like to clarify that we recommended the use of the term “corneal cross-linking” in a previous publication.2 For the sake of completeness, a comprehensive bibliography supporting this claim is added here for the journal's readers.3–6 In the same editorial, we did not agree with the term “prophylactic CXL,” which is misleading and does not have scientific or clinical support. Recommending the use of CXL in combination with corneal refractive surgery to (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - March 9, 2018 Category: Opthalmology Authors: Marco Lombardo, MD, PhD Source Type: research
Rotational Stability of Monofocal and Trifocal Intraocular Toric Lenses With Identical Design and Material but Different Surface Treatment
Approximately 30% of patients undergoing cataract surgery have preoperative corneal astigmatism of 1.00 diopters (D) or higher.1,2 The presence of astigmatism compromises postoperative visual acuity, particularly when multifocal intraocular lenses (IOLs) are implanted, thus making the correction of astigmatism exceeding 1.00 D at the time of cataract surgery3 –6 crucial for meeting patient expectations of spectacle independence. Many methods exist for reducing preoperative corneal astigmatism during cataract surgery, including toric IOL implantation. Clinical studies have shown toric lenses (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - February 12, 2018 Category: Opthalmology Authors: Kristof Vandekerckhove, MD, MBA Source Type: research
Surface Ablation Re-treatments After SMILE
We read with interest the article by Siedlecki et al. showing their results with surface ablation enhancement after myopic small incision lenticule extraction (SMILE).1 They treated a residual spherical equivalent (SE) refraction of −0.86 ±0.43 diopters (D) (range: −1.75 to 0.00 D) following SMILE by using surface ablation and mitomycin C (MMC), and obtained a mean residual SE of +0.03 ± 0.57 D 3 months after the enhancement. However, this residual SE ranged from −1.75 to +1.75 D, with 15% of patients showing more than +0.50 D of residual SE and 5% showing more than +1.00 D of SE. Another (Source: Journal of Refractive Surgery)
Source: Journal of Refractive Surgery - February 12, 2018 Category: Opthalmology Authors: Laura de Benito-Llopis, MD, PhD Source Type: research
