Can degradation products released from dental implants affect peri ‐implant tissues?
This study aimed to assess the literature available on the effects, on peri‐implant tissues, of degradation products released from dental implants as a consequence of therapeutic treatment for peri‐implantitis and/or of wear‐corrosion of titanium. A literature review of the PubMed medline database was performed up to December 31, 2016. The following search terms were used: “titanium wear and dental implant”; “titanium corrosion and dental implant”; “bio‐tribocorrosion”; “peri‐implantitis”; “treatment of peri‐implantitis”; “titanium particles release and dental implant”; and “titanium i...
Source: Journal of Periodontal Research - August 1, 2017 Category: Dentistry Authors: M. Noronha Oliveira, W. V. H. Schunemann, M. T. Mathew, B. Henriques, R. S. Magini, W. Teughels, J. C. M. Souza Tags: REVIEW ARTICLE Source Type: research
A reproducible microcosm biofilm model of subgingival microbial communities
ConclusionThis biofilm model allows reproducible production of complex subgingival microbial communities. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - July 14, 2017 Category: Dentistry Authors: M. Fernandez y Mostajo, R. A. M. Exterkate, M. J. Buijs, W. Beertsen, G. A. van der Weijden, E. Zaura, W. Crielaard Tags: ORIGINAL ARTICLE Source Type: research
Mineral trioxide aggregate improves healing response of periodontal tissue to injury in mice
ConclusionMTA promotes regeneration of injured PDL and alveolar bone, reflected as contribution of progenitors (SMA9+ cells) into osteoblasts (Col2.3GFP+ cells). In vitro, MTA‐conditioned medium fails to promote osteogenic differentiation of both PDLC and BMSC. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - July 10, 2017 Category: Dentistry Authors: I. Vidovic Zdrilic, I. O. Azevedo Queiroz, B. G. Matthews, J. E. Gomes ‐Filho, M. Mina, I. Kalajzic Tags: ORIGINAL ARTICLE Source Type: research
Proinflammatory effects and mechanisms of calprotectin on human gingival fibroblasts
ConclusionOur findings suggest that calprotectin exerts proinflammatory effects on HGFs via the S100A9 subunit and TLR4‐mediated NF‐κB and MAPK signaling pathways. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 23, 2017 Category: Dentistry Authors: H. Gao, J. Hou, H. Meng, X. Zhang, Y. Zheng, L. Peng Tags: ORIGINAL ARTICLE Source Type: research
Distinct post ‐translational features of type I collagen are conserved in mouse and human periodontal ligament
ConclusionThis distinctive post‐translational phenotype may be relevant for understanding why some individuals are at risk of rapid PDL destruction in periodontal disease and warrants further investigation. In addition, developing a murine model for studying PDL collagen may be useful for exploring potential clinical strategies for promoting PDL regeneration. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 20, 2017 Category: Dentistry Authors: D. M. Hudson, M. Garibov, D. R. Dixon, T. Popowics, D. R. Eyre Tags: ORIGINAL ARTICLE Source Type: research
The gingival biotype in a cohort of Chinese subjects with and without history of periodontal disease
ConclusionsThis study shows that gingival biotype measured by gingival thickness in subjects with treated periodontitis is significantly correlated with gingival recession. Further study could clarify the clinical implications of gingival biotype in the management of periodontal patients. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 15, 2017 Category: Dentistry Authors: F. Liu, G. Pelekos, L. J. Jin Tags: ORIGINAL ARTICLE Source Type: research
Porphyromonas gingivalis lipopolysaccharide regulates ephrin/Eph signalling in human periodontal ligament fibroblasts
ConclusionThe present study suggest that P. gingivalisLPS would contribute to a dysregulation of bone remodelling, whereby ephrinA2/EphA2 expression is stimulated and EphB4 expression is inhibited. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 7, 2017 Category: Dentistry Authors: M. Li, C. Zhang, L. Jin, K. Matsuo, Y. Yang Tags: ORIGINAL ARTICLE Source Type: research
Transgelin mediates transforming growth factor ‐β1‐induced proliferation of human periodontal ligament cells
ConclusionTransgelin is expressed in PDL tissue and might have a role in HPDLC proliferation induced by TGF‐β1 stimulation. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 7, 2017 Category: Dentistry Authors: H. Mitarai, N. Wada, D. Hasegawa, S. Yoshida, M. Sonoda, A. Tomokiyo, S. Hamano, S. Serita, H. Mizumachi, H. Maeda Tags: ORIGINAL ARTICLE Source Type: research
Oral application of a periodontal pathogen impacts SerpinE1 expression and pancreatic islet architecture in prediabetes
ConclusionOral application of the periodontal pathogen Pg to C57BL/6 mice induces periodontitis, translocation of Pg/gingipain to the pancreas and results in complex alterations in pancreatic islet morphology. SerpinE1 appears to be involved in this process. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: V. Ilievski, U. G. Bhat, S. Suleiman ‐Ata, B. A. Bauer, P. T. Toth, S. T. Olson, T. G. Unterman, K. Watanabe Tags: ORIGINAL ARTICLE Source Type: research
The intricate anatomy of the periodontal ligament and its development: Lessons for periodontal regeneration
The periodontal ligament (PDL) connects the tooth root and alveolar bone. It is an aligned fibrous network that is interposed between, and anchored to, both mineralized surfaces. Periodontal disease is common and reduces the ability of the PDL to act as a shock absorber, a barrier for pathogens and a sensor of mastication. Although disease progression can be stopped, current therapies do not primarily focus on tissue regeneration. Functional regeneration of PDL may be achieved using innovative techniques, such as tissue engineering. However, the complex fibrillar architecture of the PDL, essential to withstand high forces,...
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: T. Jong, A. D. Bakker, V. Everts, T. H. Smit Tags: REVIEW ARTICLE Source Type: research
Salivary, gingival crevicular fluid and serum levels of ghrelin and chemerin in patients with periodontitis and overweight
ConclusionLow ghrelin and high chemerin levels in the gingival crevicular fluid might be linked to periodontal disease and overweight/obesity. However, unlike IL‐1β, the levels of chemerin and ghrelin in gingival crevicular fluid are not reliable indicators of periodontal destruction. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: H. F. R. Jentsch, N. Arnold, V. Richter, J. Deschner, T. Kantyka, S. Eick Tags: ORIGINAL ARTICLE Source Type: research
Khat chewing habit produces a significant adverse effect on periodontal, oral health: A systematic review and meta‐analysis
Although there is a general agreement that a khat chewing habit produces clinicopathological changes in the oral mucosa. However there is no reliable evidence of the effects of a khat chewing habit on the periodontal tissues. Thus, authors aimed to investigate the influence of khat chewing habits on periodontal, oral health, by comparing khat chewers to non‐chewers in respect of gingival recession, periodontal pocketing depth and loss of attachment. A systematic review and meta‐analysis were conducted based on the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. We searched PubMed, the C...
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: M. S. Al ‐akhali, E. A. Al‐Moraissi Tags: REVIEW ARTICLE Source Type: research
Denervation effectively aggravates rat experimental periodontitis
ConclusionDenervation effectively aggravates ligature‐induced rat periodontitis by the NF‐κB signaling pathway for excessive production of IL‐1β and TNF‐α and increased osteoclasts for decreased OPG/RANKL ratio. The rat model of inferior alveolar nerve transection that combined ligature‐induced periodontitis provides an animal model to observe further the change of nerve‐related factors in the occurrence and development of periodontitis, so as to select positive nerve‐related factors to regulate inflammation and promote periodontal regeneration in the future. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: X. Yu, Z. Gong, Q. Lin, W. Wang, S. Liu, S. Li Tags: ORIGINAL ARTICLE Source Type: research
Effect of cross ‐linked vs non‐cross‐linked collagen membranes on bone: A systematic review
The aim of this study was to conduct a systematic review to compare the clinical outcomes of two different resorbable collagen membranes in terms of regenerated bone volume, postoperative complications and membrane degradation during bone regeneration procedures. Randomized controlled trials (RCT) or controlled trials (CT) that compared both techniques were reviewed on four electronic databases up to December 2015, a manual search was performed on the bibliography of the collected articles and the authors were contacted for additional references if undetected on the electronic and manual search. Membrane exposure was evalu...
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: J. Jim énez Garcia, S. Berghezan, J. M. M. Caramês, M. M. Dard, D. N. S. Marques Tags: REVIEW ARTICLE Source Type: research
Synergistic interactions between corrosion and wear at titanium ‐based dental implant connections: A scoping review
Two‐piece implant systems are mainly used in oral implantology involving an osseointegrated implant connected to an abutment, which supports prosthetic structures. It is well documented that the presence of microgaps, biofilms and oral fluids at the implant‐abutment connection can cause mechanical and biological complications. The aim of this review paper was to report the degradation at the implant‐abutment connection by wear and corrosion processes taking place in the oral cavity. Most of the retrieved studies evaluated the wear and corrosion (tribocorrosion) of titanium‐based materials used for implants and abut...
Source: Journal of Periodontal Research - June 1, 2017 Category: Dentistry Authors: K. Apaza ‐Bedoya, M. Tarce, C. A. M. Benfatti, B. Henriques, M. T. Mathew, W. Teughels, J. C. M. Souza Tags: Review Article Source Type: research
