Investigation of the effect of astaxanthin on alveolar bone loss in experimental periodontitis
ConclusionWithin the limits of this study, it can be suggested that astaxanthin administration may reduce alveolar bone loss by increasing osteoblastic activity and decrease osteoclastic activity in experimental periodontitis model. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - October 1, 2017 Category: Dentistry Authors: H. Balci Yuce, A. Lektemur Alpan, F. Gevrek, H. Toker Tags: ORIGINAL ARTICLE Source Type: research
Antimicrobial peptides as a possible interlink between periodontal diseases and its risk factors: A systematic review
Antimicrobial peptides (AMPs) play a critical role in controlling innate and acquired immune responses. Local dysregulation of AMP is implicated in the pathogenesis of periodontal diseases as a response to periodontal pathogen challenge. Changes in AMP expression also characterize tobacco smoking, diabetes mellitus, obesity and rheumatoid arthritis, which are established risk factors of periodontal diseases, suggesting AMP may act as putative mechanistic links between these. The aim was to evaluate and summarize critically the current evidence pertaining to interrelationships between AMPs, periodontal diseases and selected...
Source: Journal of Periodontal Research - October 1, 2017 Category: Dentistry Authors: S. Li, G. Schmalz, J. Schmidt, F. Krause, R. Haak, D. Ziebolz Tags: REVIEW ARTICLE Source Type: research
Clinical and radiographic periodontal parameters and release of collagen degradation biomarkers in naswar dippers
ConclusionWithin the limits of the present study, it may be concluded that clinical and radiographic periodontal parameters were worse among subjects in the NW group than in those of the control group. There is a higher degree of collagen breakdown in the connective tissue of subjects in the NW group as a result of naswar usage. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 20, 2017 Category: Dentistry Authors: U. Daood, T. Abduljabbar, N. Al ‐Hamoudi, Z. Akram Tags: ORIGINAL ARTICLE Source Type: research
Characterization of hyperbranched core ‐multishell nanocarriers as an innovative drug delivery system for the application at the oral mucosa
ConclusionThese findings suggested that CMS nanocarriers might be an innovative approach for topical drug delivery in the treatment of oral inflammatory diseases. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 12, 2017 Category: Dentistry Authors: J. Jager, K. Obst, S. B. Lohan, J. Viktorov, S. Staufenbiel, H. Renz, M. Unbehauen, R. Haag, S. Hedtrich, C. Teutloff, M. C. Meinke, K. Danker, H. Dommisch Tags: ORIGINAL ARTICLE Source Type: research
Matrix metalloproteinase ‐8 levels in periodontal disease patients: A systematic review
Journal of Periodontal Research,Volume 53, Issue 2, Page 156-163, April 2018. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 12, 2017 Category: Dentistry Source Type: research
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Journal of Periodontal Research,Volume 53, Issue 2, Page 156-163, April 2018. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 12, 2017 Category: Dentistry Source Type: research
Matrix metalloproteinase ‐8 levels in periodontal disease patients: A systematic review
Periodontal disease is characterized as a disorder of the oral microbiota resulting in an immune response which, in turn, leads to the destruction of periodontal tissue. Matrix metalloproteinase‐8 (MMP‐8) has been reported as the major metalloproteinase involved in periodontal disease, being present at high levels in gingival crevicular fluid and salivary fluid (SF). The aim of this systematic review was to evaluate the scientific literature regarding the expression of MMP‐8 in gingival crevicular fluid and SF in patients with periodontal disease, analyzing its validity as a possible biomarker in the diagnosis of per...
Source: Journal of Periodontal Research - September 12, 2017 Category: Dentistry Authors: E. F. Morais, J. C. Pinheiro, R. B. Leite, P. P. A. Santos, C. A. G. Barboza, R. A. Freitas Tags: REVIEW ARTICLE Source Type: research
Differences between inflammatory and catabolic mediators of peri ‐implantitis and periodontitis lesions following initial mechanical therapy: An exploratory study
ConclusionsThis study suggests that peri‐implantitis and periodontitis connective tissues exhibit differences in response to non‐surgical treatment, which may contribute to a different pattern of disease evolution. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 12, 2017 Category: Dentistry Authors: M. Ghighi, A. Llorens, B. Baroukh, C. Chaussain, P. Bouchard, M. Gosset Tags: ORIGINAL ARTICLE Source Type: research
Role of toll ‐like receptor 2 in inflammation and alveolar bone loss in experimental peri‐implantitis versus periodontitis
ConclusionThis study suggests that TLR‐2 mediates bone loss in both peri‐implantitis and periodontitis. However, different molecular features may exist in the pathogenesis of the two diseases. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 5, 2017 Category: Dentistry Authors: X. Yu, Y. Hu, M. Freire, P. Yu, T. Kawai, X. Han Tags: ORIGINAL ARTICLE Source Type: research
Does the adjunctive use of statins provide additional benefits to nonsurgical periodontal treatment? A systematic review and meta ‐analysis
Adjunctive therapeutic agents may be used to improve the response to nonsurgical periodontal therapy. Local delivery of statins (simvastatin, artovastatin and rosuvastatin) is a promising adjunct to scaling and root planing (SRP). Thus, the aim of this review is to evaluate if adjunctive local delivery of statins is more effective than SRP alone. Randomized clinical trials that presented a test group evaluating local delivery of statins as adjuncts in healthy, diabetic and smoking patients were included. Medline and the Cochrane library database were searched up to November 2016. Random effects meta‐analyses were conduct...
Source: Journal of Periodontal Research - September 5, 2017 Category: Dentistry Authors: L. M. B. Ambr ósio, E. S. Rovai, D. I. Sendyk, M. Holzhausen, C. M. Pannuti Tags: REVIEW ARTICLE Source Type: research
Simvastatin exerts antiproliferative and differentiating effects on MG63 osteoblast ‐like cells: Morphological and immunocytochemical study
ConclusionMG63 cells cultured with simvastatin for 72 hours undergo morphological and surface changes. Simvastatin treatment exerts antiproliferative and differentiating effects on these cells as well as promoting recovery of cellular homeostasis. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - September 4, 2017 Category: Dentistry Authors: A. Magan ‐Fernandez, J. E. Fernández‐Barbero, F. O’ Valle, R. Ortiz, P. Galindo‐Moreno, F. Mesa Tags: ORIGINAL ARTICLE Source Type: research
Attributes of Bio ‐Oss® and Moa‐Bone® graft materials in a pilot study using the sheep maxillary sinus model
ConclusionBoth materials supported osseous healing and maturation without inflammation. Moa‐Bone® showed marked osteoclast activity after 4 and 6 weeks and demonstrated positive attributes for grafting, if complete remodeling of the graft within the site is desired. Further optimization of Moa‐Bone® for maxillofacial applications is warranted. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - August 1, 2017 Category: Dentistry Authors: M. M. Smith, W. J. Duncan, D. E. Coates Tags: ORIGINAL ARTICLE Source Type: research
Platelet ‐rich fibrin/aspirin complex promotes alveolar bone regeneration in periodontal defect in rats
ConclusionAspirin/salicylic acid could be sustained‐released from PRF/aspirin complex, which could inhibit inflammation and improve the function of mesenchymal cells. The data might provide a new safe and easy clinical therapeutic strategy to promote periodontal bone reparation. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - August 1, 2017 Category: Dentistry Authors: J. Du, S. Mei, L. Guo, Y. Su, H. Wang, Y. Liu, Z. Zhao, S. Wang, Y. Liu Tags: ORIGINAL ARTICLE Source Type: research
Tumor necrosis factor ‐alpha inhibits osteogenic differentiation of pre‐osteoblasts by downregulation of EphB4 signaling via activated nuclear factor‐kappaB signaling pathway
ConclusionTNF‐α inhibits osteogenic differentiation of pre‐osteoblasts by downregulation of EphB4 signaling via activated NF‐κB signaling pathway. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - August 1, 2017 Category: Dentistry Authors: L. M. Wang, N. Zhao, J. Zhang, Q. F. Sun, C. Z. Yang, P. S. Yang Tags: ORIGINAL ARTICLE Source Type: research
Modulation of periodontitis progression using pH ‐responsive nanosphere encapsulating metronidazole or N‐phenacylthialzolium bromide
ConclusionPLGA/chitosan nanospheres encapsulating metronidazole or PTB showed potential for modulating periodontitis progression. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - August 1, 2017 Category: Dentistry Authors: J. ‐H. Lin, F. Feng, M.‐C. Yu, C.‐H. Wang, P.‐C. Chang Tags: ORIGINAL ARTICLE Source Type: research
