Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta ‐analysis of preclinical in vivo trials
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - December 6, 2017 Category: Dentistry Source Type: research

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Journal of Periodontal Research, Ahead of Print. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - December 6, 2017 Category: Dentistry Source Type: research

Feasibility of the salivary transcriptome as a novel biomarker in determining disease susceptibility
ConclusionThis study showed that minimal amounts of human RNA were able to be isolated from the saliva of patients with periodontitis as well as controls. Further work is required to enhance the extraction process of human mRNA from saliva if the salivary transcriptome is to be used in determining individual patient susceptibility. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - December 1, 2017 Category: Dentistry Authors: M. F. H. Hidayat, T. Milne, M. P. Cullinan, G. J. Seymour Tags: ORIGINAL ARTICLE Source Type: research

The severity of periodontitis and metabolic syndrome in Korean population: The Dong ‐gu study
ConclusionIncreasing the severity of periodontitis was associated with the risk of prevalent MetS in Korean adults. This result confirmed that periodontal inflammation might be a contributive factor of MetS. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - December 1, 2017 Category: Dentistry Authors: O. S. Kim, M. H. Shin, S. S. Kweon, Y. H. Lee, O. J. Kim, Y. J. Kim, H. J. Chung Tags: ORIGINAL ARTICLE Source Type: research

Statins in nonsurgical and surgical periodontal therapy. A systematic review and meta ‐analysis of preclinical in vivo trials
The cholesterol‐lowering drugs, statins, possess anti‐inflammatory, antimicrobial and pro‐osteogenic properties, and thus have been tested as an adjunct to periodontal treatment. The present systematic review aimed to answer the following focused research question: What is the effect of local and/or systemic statin use on periodontal tissues in preclinical in vivo studies of experimentally induced periodontitis (EIP) and/or acute/chronified periodontal defect (ACP) models? A literature search (of Medline/PubMed, Embase/Ovid, CENTRAL/Ovid) using the following main eligibility criteria was performed: (i) English or Ger...
Source: Journal of Periodontal Research - December 1, 2017 Category: Dentistry Authors: K. Bertl, I. Steiner, N. Pandis, K. Buhlin, B. Klinge, A. Stavropoulos Tags: REVIEW ARTICLE Source Type: research

Advanced glycation end ‐products increase IL‐6 and ICAM‐1 expression via RAGE, MAPK and NF‐κB pathways in human gingival fibroblasts
ConclusionAGEs increase IL‐6 and ICAM‐1 expression via the RAGE, MAPK and NF‐κB pathways in HGFs and may exacerbate the progression of the pathogenesis of periodontal diseases. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 30, 2017 Category: Dentistry Authors: K. Nonaka, Y. Kajiura, M. Bando, E. Sakamoto, Y. Inagaki, J. H. Lew, K. Naruishi, T. Ikuta, K. Yoshida, T. Kobayashi, H. Yoshie, T. Nagata, J. Kido Tags: ORIGINAL ARTICLE Source Type: research

Advanced glycation end ‐products increase IL‐6 and ICAM‐1 expression via RAGE, MAPK and NF‐κB pathways in human gingival fibroblasts
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 30, 2017 Category: Dentistry Source Type: research

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Journal of Periodontal Research, Ahead of Print. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 30, 2017 Category: Dentistry Source Type: research

Association between height and periodontitis in Korean adults: Results from KNHANES IV and V
ConclusionOur study shows that there is an inverse association between height and severe periodontitis only in the younger Korean birth cohort. Our results support the impact of height, as an early childhood environmental indicator, on severe periodontitis in adulthood. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 21, 2017 Category: Dentistry Authors: S. ‐H. Shim, D.‐H. Han Tags: ORIGINAL ARTICLE Source Type: research

Association between height and periodontitis in Korean adults: Results from KNHANES IV and V
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 20, 2017 Category: Dentistry Source Type: research

Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells
Journal of Periodontal Research, EarlyView. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 20, 2017 Category: Dentistry Source Type: research

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Journal of Periodontal Research, Ahead of Print. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 20, 2017 Category: Dentistry Source Type: research

Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells
ConclusionDental calculus induces pyroptotic cell death in human oral epithelial cells and the crystalline structure plays a major role in this process. Oral epithelial cell death induced by dental calculus might be important for the etiology of periodontitis. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 20, 2017 Category: Dentistry Authors: S. M. Ziauddin, A. Yoshimura, J. L. Montenegro Raudales, Y. Ozaki, K. Higuchi, T. Ukai, T. Kaneko, T. Miyazaki, E. Latz, Y. Hara Tags: ORIGINAL ARTICLE Source Type: research

Associations among tooth loss, systemic inflammation and antibody titers to periodontal pathogens in Japanese patients with cardiovascular disease
ConclusionThe patients with 1‐9 teeth had the highest level of C‐reactive protein among the four groups, and the patients with 10‐19 teeth had the highest level of IgG to periodontal bacteria. We conclude that the number of remaining teeth may be used to estimate the severity of systemic inflammation in patients with CVD. (Source: Journal of Periodontal Research)
Source: Journal of Periodontal Research - November 15, 2017 Category: Dentistry Authors: N. Aoyama, J. ‐I. Suzuki, N. Kobayashi, T. Hanatani, N. Ashigaki, A. Yoshida, Y. Shiheido, H. Sato, M. Minabe, Y. Izumi, M. Isobe Tags: ORIGINAL ARTICLE Source Type: research