High glucocorticoid levels during gestation activate the inflammasome in hippocampal oligodendrocytes of the offspring
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 16, 2016 Category: Neurology Authors: Carola J. Maturana, Adam Aguirre, Juan C. Sáez Tags: Research Article Source Type: research
Gap junctions in C. elegans: Their roles in behavior and development
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 14, 2016 Category: Neurology Authors: David H. Hall Tags: Review Article Source Type: research
Cyclic Nucleotide Signaling is Required during Synaptic Refinement at the Drosophila Neuromuscular Junction
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 10, 2016 Category: Neurology Authors: Fernando Vonhoff, Haig Keshishian Tags: Research Article Source Type: research
Blocking elevated VEGF ‐A attenuates non‐vasculature Fragile X syndrome abnormalities
Abstract
Fragile X syndrome (FXS) is the most common form of inherited mental retardation. In exploring abnormalities associated with the syndrome, we have recently demonstrated abnormal vascular density in a FXS mouse model (Galvan and Galvez, ). One of the most prominent regulators of vascular growth is VEGF‐A (Vascular Endothelial Growth Factor A), suggesting that FXS is associated with abnormal VEGF‐A expression. In addition to its role in vascular regulation, VEGF‐A also induces cellular changes such as increasing cell proliferation, and axonal and neurite outgrowth independent of its effects on vasculature. The...
Source: Journal of Neurobiology - June 9, 2016 Category: Neurology Authors: Amogh P. Belagodu, Liridon Zendeli, Bernard J. Slater, Roberto Galvez Tags: Research Article Source Type: research
Issue Information ‐ TOC
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 8, 2016 Category: Neurology Tags: Issue Information ‐ TOC Source Type: research
Cover Image
(Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 8, 2016 Category: Neurology Tags: Cover Image Source Type: research
dHb9 expressing larval motor neurons persist through metamorphosis to innervate adult ‐specific muscle targets and function in Drosophila eclosion
ABSTRACT
The Drosophila larval nervous system is radically restructured during metamorphosis to produce adult specific neural circuits and behaviors. Genesis of new neurons, death of larval neurons and remodeling of those neurons that persistent collectively act to shape the adult nervous system. Here, we examine the fate of a subset of larval motor neurons during this restructuring process. We used a dHb9 reporter, in combination with the FLP/FRT system to individually identify abdominal motor neurons in the larval to adult transition using a combination of relative cell body location, axonal position, and muscle targets....
Source: Journal of Neurobiology - June 5, 2016 Category: Neurology Authors: Soumya Banerjee, Marcus Toral, Matthew Siefert, David Conway, Meredith Dorr, Joyce Fernandes Tags: Research Article Source Type: research
Oxytocin receptor dynamics in the brain across development and species
ABSTRACT
Oxytocin (OXT) signaling through the OXT receptor plays a significant role in a variety of physiological processes throughout the lifespan. OXT's effects depend on the tissue distribution of the receptor. This tissue specificity is dynamic and changes across development, and also varies with sex, experience, and species. The purpose of this review is to highlight these themes with examples from several life stages and several species. Important knowledge gaps will also be emphasized. Understanding the effective sites of action for OXT via its receptor will help refine hypotheses about the roles of this important n...
Source: Journal of Neurobiology - June 5, 2016 Category: Neurology Authors: Radhika Vaidyanathan, Elizabeth A.D. Hammock Tags: Review Article Source Type: research
Gap Junctional Signaling in Pattern Regulation: Physiological network connectivity instructs growth and form
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - June 5, 2016 Category: Neurology Authors: Juanita Mathews, Michael Levin Tags: Review Article Source Type: research
Effect of nutrient availability on progenitor cells in zebrafish (Danio rerio)
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - May 31, 2016 Category: Neurology Authors: Tibiábin Benítez‐Santana, Matthieu Simion, Geneviève orraze, Françoise Médale, Jean‐Stéphane Joly Tags: Research Article Source Type: research
Blocking elevated VEGF‐A attenuates non‐vasculature Fragile X Syndrome abnormalities
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - May 31, 2016 Category: Neurology Authors: Amogh P. Belagodu, Liridon Zendeli, Bernard J. Slater, Roberto Galvez Tags: Research Article Source Type: research
Dual role for Sox2 in specification of sensory competence and regulation of Atoh1 function
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - May 20, 2016 Category: Neurology Authors: Chandrakala Puligilla, Matthew W. Kelley Tags: Research Article Source Type: research
dHb9 expressing larval motor neurons persist through metamorphosis to innervate adult‐specific muscle targets and function in Drosophila eclosion
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - May 11, 2016 Category: Neurology Authors: Soumya Banerjee, Marcus Toral, Matthew Siefert, David Conway, Meredith Dorr, Joyce Fernandes Tags: Research Article Source Type: research
Hepatocyte nuclear factor ‐4 alpha in noise‐induced cochlear neuropathy
ABSTRACT
Noise‐induced hearing loss (NIHL) is a problem of profound clinical significance and growing magnitude. Alarmingly, even moderate noise levels, previously assumed to cause only temporary shifts in auditory thresholds (“temporary” NIHL), are now known to cause cochlear synaptopathy and subsequent neuropathy. To uncover molecular mechanisms of this neuropathy, a network analysis of genes reported to have significantly altered expression after temporary threshold shift‐inducing noise exposure was performed. The transcription factor Hepatocyte Nuclear Factor‐4 alpha (HNF4α), which had not previously been st...
Source: Journal of Neurobiology - May 8, 2016 Category: Neurology Authors: Jane Bjerg Groth, Shyan ‐Yuan Kao, Martijn C. Briët, Konstantina M. Stankovic Tags: Research Article Source Type: research
The chromatin modifying complex CoREST/LSD1 negatively regulates Notch pathway during cerebral cortex development
This article is protected by copyright. All rights reserved. (Source: Journal of Neurobiology)
Source: Journal of Neurobiology - April 26, 2016 Category: Neurology Authors: Cecilia I. Lopez, Katherine E. Saud, Rodrigo Aguilar, F. Andrés Berndt, José Cánovas, Martín Montecino, Manuel Kukuljan Tags: Research Article Source Type: research
