Rhythmical massage improves autonomic nervous system function: a single-blind randomised controlled trial
ConclusionRMT causes specific and marked stimulation of the autonomic nervous system. Use of a medicinal aromatic oil had only a temporary effect on HRV, indicating that the RM causes the most relevant long-term effect. The effect is relatively specific, as the physiological effects seen in the group of subjects who received only SM were considerably less pronounced.Trial registrationRegistration trial DRKS00004164 on DRKS. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

A historical evaluation of Chinese tongue diagnosis in the treatment of septicemic plague in the pre-antibiotic era, and as a new direction for revolutionary clinical research applications
This article focuses on the historical development of what is the world’s earliest tongue diagnosis monograph, and discusses the directions that such knowledge may be used in future clinical research. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Eric Wei Chiang Chan, Siu Kuin Wong, Hung Tuck ChanAbstractThis short review provides an update of the anticancer and anti-inflammatory properties of casticin from Vitex species. Casticin is a polymethylflavone with three rings, an orthocatechol moiety, a double bond, two hydroxyl groups and four methoxyl groups. Casticin has been isolated from various tissues of plants in the Vitex genus: fruits and leaves of V. trifolia, aerial parts and seeds of V. agnus-castus and leaves of V. negundo. Studies have reported the antiprolifera...
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Phytochemical profile and pharmacological activity of Aegle marmelos Linn.
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Bikash Manandhar, Keshav Raj Paudel, Biraj Sharma, Rajendra KarkiAbstractAegle marmelos Linn. (Rutaceae), commonly known as “bael” in Nepal and India, is a valuable medicinal plant and is considered sacred by the Hindus. It is used to cure several diseases in the Indian traditional medicine system of Ayurveda and has had similar uses among many ethnic communities residing in Indian subcontinent for over 5000 years. Its leaves, bark, stem, fruits and seeds have been used for various medicinal purposes. Bael fruits are espec...
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Patient blinding with blunt tip placebo acupuncture needles: comparison between 1 mm and 2 mm skin press
ConclusionPlacebo needles of 2 mm press made more subjects guess that the needles penetrated the skin than 1 mm press needles. The use of small diameter needles increased patient blinding. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome: a randomized, double-blind, placebo-controlled trial
ConclusionThe responses of insulin and HOMA-IR to ALE supplementation have shown an interaction with single-nucleotide polymorphism rs7903146 in TCF7L2.Trial registrationIranian Registry of Clinical Trial IRCT201409033320N9. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Effects of vitamin supplementation on inflammatory markers and psychological wellbeing among distressed women: a randomized controlled trial
ConclusionThe results suggest that administration of multivitamins was not effective in improving psychological state. However, some evidence supported the positive impact of multivitamin supplementation on pro-inflammatory cytokine profiles of women currently experiencing stress. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Acupuncture for migraine without aura: a systematic review and meta-analysis
ConclusionOur meta-analysis shows that the effectiveness of acupuncture is still uncertain, but it might be relatively safer than medication therapy in the treatment and prophylaxis of MWoA. Further proof is needed. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Medicinal plants from the Brazilian Amazonian region and their antileishmanial activity: a review
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Bruno José Martins Da Silva, Amanda Anastácia Pinto Hage, Edilene Oliveira Silva, Ana Paula Drummond RodriguesAbstractLeishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosine and liposomal amphotericin B is currently the only effective treatment. However, adverse effects, long-term treatment and the emergence of parasite resistance have led to the search for ...
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Hot aqueous leaf extract of Lasianthera africana (Icacinaceae) attenuates rifampicin-isoniazid-induced hepatotoxicity
ConclusionThis study demonstrated that HALA leaf extract attenuated RIF-INH-induced hepatotoxicity. L. africana could be exploited in management of RIF-INH-induced hepatitis. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Feiji Recipe inhibits the growth of lung cancer by modulating T-cell immunity through indoleamine-2,3-dioxygenase pathway in an orthotopic implantation model
ConclusionThe molecular mechanism of Feiji Recipe in treatment of lung cancer is to restore the function of T-cells in the cancer microenvironment through interfering with the IDO pathway. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Preliminary optimization of a Chinese herbal medicine formula based on the neuroprotective effects in a rat model of rotenone-induced Parkinson’s disease
ConclusionThe investigated formulations of Chinese herbs had neuroprotective effects against PD models, and the neuroprotective effects were weakly related to the proportion of key herbs. However the neuroprotective effects of the formula may not result from a single active constituent. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Evaluation of phenolic composition, antioxidant, anti-inflammatory and anticancer activities of Polygonatum verticillatum (L.)
ConclusionFrom the present study, it can be concluded that P. verticillatum possessed remarkable antioxidant, anti-inflammatory, and anticancer activities, which could be due to different secondary metabolites of the plant. Phenolic compounds are likely responsible for antioxidant and anti-inflammatory activities. However, flavonoids and other compounds might contribute to the anticancer potential of the plant. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Phytochemistry and biological activities of Heracleum persicum: a review
This article has provided comprehensive information on Iranian traditional uses, phytochemistry and pharmacological activities of H. persicum. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research

Clinical practice guidelines for the treatment of primary liver cancer with integrative traditional Chinese and Western medicine
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Chang-quan Ling, Jia Fan, Hong-sheng Lin, Feng Shen, Zhen-ye Xu, Li-zhu Lin, Shu-kui Qin, Wei-ping Zhou, Xiao-feng Zhai, Bai Li, Qing-hui Zhou, on behalf of the Chinese Integrative Therapy of Primary Liver Cancer Working GroupAbstractTraditional Chinese medicine (TCM) is an important part of the treatment of primary liver cancer (PLC) in China; however, the current instructions for the integrative use of traditional Chinese and Western medicine for PLC are mostly based on expert opinion. There is no evidence-based guideline for...
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research