Feiji Recipe inhibits the growth of lung cancer by modulating T-cell immunity through indoleamine-2,3-dioxygenase pathway in an orthotopic implantation model
ConclusionThe molecular mechanism of Feiji Recipe in treatment of lung cancer is to restore the function of T-cells in the cancer microenvironment through interfering with the IDO pathway. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Preliminary optimization of a Chinese herbal medicine formula based on the neuroprotective effects in a rat model of rotenone-induced Parkinson’s disease
ConclusionThe investigated formulations of Chinese herbs had neuroprotective effects against PD models, and the neuroprotective effects were weakly related to the proportion of key herbs. However the neuroprotective effects of the formula may not result from a single active constituent. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Evaluation of phenolic composition, antioxidant, anti-inflammatory and anticancer activities of Polygonatum verticillatum (L.)
ConclusionFrom the present study, it can be concluded that P. verticillatum possessed remarkable antioxidant, anti-inflammatory, and anticancer activities, which could be due to different secondary metabolites of the plant. Phenolic compounds are likely responsible for antioxidant and anti-inflammatory activities. However, flavonoids and other compounds might contribute to the anticancer potential of the plant. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Phytochemistry and biological activities of Heracleum persicum: a review
This article has provided comprehensive information on Iranian traditional uses, phytochemistry and pharmacological activities of H. persicum. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Clinical practice guidelines for the treatment of primary liver cancer with integrative traditional Chinese and Western medicine
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Chang-quan Ling, Jia Fan, Hong-sheng Lin, Feng Shen, Zhen-ye Xu, Li-zhu Lin, Shu-kui Qin, Wei-ping Zhou, Xiao-feng Zhai, Bai Li, Qing-hui Zhou, on behalf of the Chinese Integrative Therapy of Primary Liver Cancer Working GroupAbstractTraditional Chinese medicine (TCM) is an important part of the treatment of primary liver cancer (PLC) in China; however, the current instructions for the integrative use of traditional Chinese and Western medicine for PLC are mostly based on expert opinion. There is no evidence-based guideline for...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Kaempferia parviflora ethanol extract improves self-assessed sexual health in men: a pilot study
ConclusionOur results suggest that KaempMax™ may improve erectile function in healthy middle-aged and older men. While the effects were not as pronounced as what might be seen with prescription medication, most participants found them satisfactory. Additional, longer and placebo-controlled clinical trials will be needed.Trial registrationClinicaltrials.gov identifier NCT03389867. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
In vitro antioxidant, antilipoxygenase and antimicrobial activities of extracts from seven climbing plants belonging to the Bignoniaceae
ConclusionMost of the extracts exhibited antioxidant activity as well as in vitro inhibition of lipoxygenase. The excellent antimicrobial activity of T. selloi and F. chica supports their use in traditional medicine as antiseptic agents. The extracts of F. caudigera and C. convoluta, both with notable biological activities in this study, could be used as herbal remedies for skin care. In addition, this study provides, for the first time, information about phenolic compounds present in C. convoluta. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Bioavailable curcumin formulations: A review of pharmacokinetic studies in healthy volunteers
Publication date: Available online 4 July 2018Source: Journal of Integrative MedicineAuthor(s): Rohitash JamwalAbstractCurcumin is a widely studied natural compound which has shown tremendous in vitro therapeutic potential. Despite that, the clinical efficacy of the native curcumin is weak due to its low bioavailability and high metabolism in the gastrointestinal tract. During the last decade, researchers have come up with different formulations with a focus on improving the bioavailability of curcumin. As a result, a significant number of bioavailable curcumin-based formulations were introduced with the varying range of e...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Evaluation of acute and subacute toxicity of whole-plant aqueous extract of Vernonia mespilifolia Less. in Wistar rats
ConclusionThese results shown that AEVM at dosage levels up to 600 mg/kg is nontoxic and could also offer protection on some body tissues. AEVM could, therefore, be considered safe. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Ethnomedicinal, phytochemical and pharmacological updates on Hygrophila auriculata (Schum.) Hiene: an overview
This article explores the most recent evidence-based information on ethanomedicinal, phytochemical and pharmacological understanding of Hygrophila auriculata for the treatment of various diseases and health conditions. Various ethanomedicinal writings suggest the use of the plant or its parts for the treatment of jaundice, edema, gastrointestinal ailments, diarrhea, dysentery, urinogenital disorder, gall stones, urinary calculi, kidney stone, leucorrhoea, rheumatism, tuberculosis, anemia, body pain, constipation and skin disease, and as an aphrodisiac. The plant has been reported to contain flavonoids (apigenin, luteolin, ...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Phytochemical characterization of polyphenolic compounds with HPLC–DAD–ESI–MS and evaluation of lipid-lowering capacity of aqueous extracts from Saharan plant Anabasis aretioides (Coss & Moq.) in normal and streptozotocin-induced diabetic rats
ConclusionAqueous A. aretioides APAE exhibits lipid-lowering and in vitro antioxidant activities. Many polyphenols were present in this extract and these phytoconstituents may be involved in the pharmacological activity of this plant. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research
Home care with acupuncture increased the quality of life in a patient with advanced cancer with neuropathic pain induced by bone metastasis: a case report
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Ching-Feng SuAbstractA 66-year-old female patient was diagnosed with hepatocellular carcinoma accompanied by neuropathic pain induced by a metastatic tumor that compromised root and spinal canal. Although her pain was relieved following medical treatment, breakthrough pain occurring 1–2 times a day was still distressing. Neuropathic pain in her right lower limb caused discomfort and irritability and decreased her quality of life. We had limited options to adjust her prescription drug regime, due to the side effect of these dru...
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research
Noni (Morinda citrifolia L.) fruit juice delays immunosenescence in the lymphocytes in lymph nodes of old F344 rats
ConclusionThese results suggest that the immunostimulatory properties of NFJ are facilitated through intracellular signaling pathways involving ERK1/2, Akt and NF-κB. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research
Inhibitory potentials of phenolic-rich extracts from Bridelia ferruginea on two key carbohydrate-metabolizing enzymes and Fe2+-induced pancreatic oxidative stress
ConclusionThe phenolic-rich extracts of BF leaves showed antioxidant potentials and inhibited two key carbohydrate-metabolizing enzymes in vitro. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research
Double-blind evaluation of homeopathy on cocaine craving: a randomized controlled pilot study
ConclusionsA psychosocial rehabilitation setting improved recruitment but was not sufficient to decrease dropout frequency among Brazilian cocaine treatment seekers. Psychosocial rehabilitation plus homeopathic Q-potencies of opium and E. coca were more effective than psychosocial rehabilitation alone in reducing cocaine cravings. Due to high dropout rate and risk of bias, further research is required to confirm our findings, with specific focus on strategies to increase patient retention.Trial registrationRBR-2xzcwz (http://www.ensaiosclinicos.gov.br). (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 5, 2018 Category: Complementary Medicine Source Type: research
