Phytochemical characterization of polyphenolic compounds with HPLC–DAD–ESI–MS and evaluation of lipid-lowering capacity of aqueous extracts from Saharan plant Anabasis aretioides (Coss & Moq.) in normal and streptozotocin-induced diabetic rats
ConclusionAqueous A. aretioides APAE exhibits lipid-lowering and in vitro antioxidant activities. Many polyphenols were present in this extract and these phytoconstituents may be involved in the pharmacological activity of this plant. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Home care with acupuncture increased the quality of life in a patient with advanced cancer with neuropathic pain induced by bone metastasis: a case report
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Ching-Feng SuAbstractA 66-year-old female patient was diagnosed with hepatocellular carcinoma accompanied by neuropathic pain induced by a metastatic tumor that compromised root and spinal canal. Although her pain was relieved following medical treatment, breakthrough pain occurring 1–2 times a day was still distressing. Neuropathic pain in her right lower limb caused discomfort and irritability and decreased her quality of life. We had limited options to adjust her prescription drug regime, due to the side effect of these dru...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Noni (Morinda citrifolia L.) fruit juice delays immunosenescence in the lymphocytes in lymph nodes of old F344 rats
ConclusionThese results suggest that the immunostimulatory properties of NFJ are facilitated through intracellular signaling pathways involving ERK1/2, Akt and NF-κB. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Inhibitory potentials of phenolic-rich extracts from Bridelia ferruginea on two key carbohydrate-metabolizing enzymes and Fe2+-induced pancreatic oxidative stress
ConclusionThe phenolic-rich extracts of BF leaves showed antioxidant potentials and inhibited two key carbohydrate-metabolizing enzymes in vitro. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Double-blind evaluation of homeopathy on cocaine craving: a randomized controlled pilot study
ConclusionsA psychosocial rehabilitation setting improved recruitment but was not sufficient to decrease dropout frequency among Brazilian cocaine treatment seekers. Psychosocial rehabilitation plus homeopathic Q-potencies of opium and E. coca were more effective than psychosocial rehabilitation alone in reducing cocaine cravings. Due to high dropout rate and risk of bias, further research is required to confirm our findings, with specific focus on strategies to increase patient retention.Trial registrationRBR-2xzcwz (http://www.ensaiosclinicos.gov.br). (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Rhythmical massage improves autonomic nervous system function: a single-blind randomised controlled trial
ConclusionRMT causes specific and marked stimulation of the autonomic nervous system. Use of a medicinal aromatic oil had only a temporary effect on HRV, indicating that the RM causes the most relevant long-term effect. The effect is relatively specific, as the physiological effects seen in the group of subjects who received only SM were considerably less pronounced.Trial registrationRegistration trial DRKS00004164 on DRKS. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
A historical evaluation of Chinese tongue diagnosis in the treatment of septicemic plague in the pre-antibiotic era, and as a new direction for revolutionary clinical research applications
This article focuses on the historical development of what is the world’s earliest tongue diagnosis monograph, and discusses the directions that such knowledge may be used in future clinical research. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Casticin from Vitex species: a short review on its anticancer and anti-inflammatory properties
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Eric Wei Chiang Chan, Siu Kuin Wong, Hung Tuck ChanAbstractThis short review provides an update of the anticancer and anti-inflammatory properties of casticin from Vitex species. Casticin is a polymethylflavone with three rings, an orthocatechol moiety, a double bond, two hydroxyl groups and four methoxyl groups. Casticin has been isolated from various tissues of plants in the Vitex genus: fruits and leaves of V. trifolia, aerial parts and seeds of V. agnus-castus and leaves of V. negundo. Studies have reported the antiprolifera...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Phytochemical profile and pharmacological activity of Aegle marmelos Linn.
Publication date: May 2018Source: Journal of Integrative Medicine, Volume 16, Issue 3Author(s): Bikash Manandhar, Keshav Raj Paudel, Biraj Sharma, Rajendra KarkiAbstractAegle marmelos Linn. (Rutaceae), commonly known as “bael” in Nepal and India, is a valuable medicinal plant and is considered sacred by the Hindus. It is used to cure several diseases in the Indian traditional medicine system of Ayurveda and has had similar uses among many ethnic communities residing in Indian subcontinent for over 5000 years. Its leaves, bark, stem, fruits and seeds have been used for various medicinal purposes. Bael fruits are espec...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Patient blinding with blunt tip placebo acupuncture needles: comparison between 1 mm and 2 mm skin press
ConclusionPlacebo needles of 2 mm press made more subjects guess that the needles penetrated the skin than 1 mm press needles. The use of small diameter needles increased patient blinding. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
TCF7L2-rs7903146 polymorphism modulates the effect of artichoke leaf extract supplementation on insulin resistance in metabolic syndrome: a randomized, double-blind, placebo-controlled trial
ConclusionThe responses of insulin and HOMA-IR to ALE supplementation have shown an interaction with single-nucleotide polymorphism rs7903146 in TCF7L2.Trial registrationIranian Registry of Clinical Trial IRCT201409033320N9. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Effects of vitamin supplementation on inflammatory markers and psychological wellbeing among distressed women: a randomized controlled trial
ConclusionThe results suggest that administration of multivitamins was not effective in improving psychological state. However, some evidence supported the positive impact of multivitamin supplementation on pro-inflammatory cytokine profiles of women currently experiencing stress. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Acupuncture for migraine without aura: a systematic review and meta-analysis
ConclusionOur meta-analysis shows that the effectiveness of acupuncture is still uncertain, but it might be relatively safer than medication therapy in the treatment and prophylaxis of MWoA. Further proof is needed. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Medicinal plants from the Brazilian Amazonian region and their antileishmanial activity: a review
Publication date: July 2018Source: Journal of Integrative Medicine, Volume 16, Issue 4Author(s): Bruno José Martins Da Silva, Amanda Anastácia Pinto Hage, Edilene Oliveira Silva, Ana Paula Drummond RodriguesAbstractLeishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosine and liposomal amphotericin B is currently the only effective treatment. However, adverse effects, long-term treatment and the emergence of parasite resistance have led to the search for ...
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
Hot aqueous leaf extract of Lasianthera africana (Icacinaceae) attenuates rifampicin-isoniazid-induced hepatotoxicity
ConclusionThis study demonstrated that HALA leaf extract attenuated RIF-INH-induced hepatotoxicity. L. africana could be exploited in management of RIF-INH-induced hepatitis. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - July 10, 2018 Category: Complementary Medicine Source Type: research
