Halalopathy: a science of trust in medicine
This study enlightens laws of compatibility to initiate a domino chain effect to activate placebo effects and lower the body’s entropy. The healing power of each effect will contribute to the healing process and enhance the total drug effects.Please cite this article as: Alzeer J. Halalopathy: a science of trust in medicine. J Integr Med. 2019; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 25, 2019 Category: Complementary Medicine Source Type: research
Induction of apoptosis in leukemic cells by the alkaloid extract of garden cress (Lepidium sativum L.)
ConclusionThe ability of the alkaloid extract of L. sativum seeds to induce apoptosis indicates a potential pharmacological use in cancer chemotherapy. The separation of individual active compounds and further in-depth exploration of the molecular mechanism of apoptosis may lead to novel chemotherapeutic compounds in our future antineoplastic research. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 25, 2019 Category: Complementary Medicine Source Type: research
Ursolic acid: an overview on its cytotoxic activities against breast and colorectal cancer cells
Publication date: Available online 18 March 2019Source: Journal of Integrative MedicineAuthor(s): Eric Wei Chiang Chan, Chu Yong Soon, Joash Ban Lee Tan, Siu Kuin Wong, Yew Woh HuiAbstractUrsolic acid (UA) is a pentacyclic triterpene of the ursane type. As a common chemical constituent among species of the family Lamiaceae, UA possesses a broad spectrum of pharmacological properties. This overview focuses on the anticancer properties of UA against breast cancer (BC) and colorectal cancer (CRC) that are most common among women and men, respectively. In vitro studies have shown that UA inhibited the growth of BC and CRC cell...
Source: Journal of Integrative Medicine - March 20, 2019 Category: Complementary Medicine Source Type: research
Fire-needle acupuncture for upper limb spastic paralysis after stroke: study protocol for a randomized controlled trial
This study will evaluate the effects of fire-needle acupuncture for ULSP in the context of standardized clinical research and provide high-quality data to inform clinical procedures and future study design.Methods/DesignA randomized controlled trial will be carried out to evaluate the effects of fire-needle acupuncture therapy in patients with ULSP from stroke. ULSP patients (n = 120) will be recruited at Changhai Hospital in Shanghai, China. Patients will be randomly divided into three groups, including fire-needle acupuncture group (FAG), filiform-needle acupuncture group (FFAG) and rehabilitation treatment group (RTG). ...
Source: Journal of Integrative Medicine - March 20, 2019 Category: Complementary Medicine Source Type: research
Editorial Board
Publication date: March 2019Source: Journal of Integrative Medicine, Volume 17, Issue 2Author(s): (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 16, 2019 Category: Complementary Medicine Source Type: research
Discovery and preclinical development of IIIM-160, a Bergenia ciliata-based anti-inflammatory and anti-arthritic botanical drug candidate
ConclusionThe dual-activity of IL-6 inhibition and antinociception marks the suitability of IIIM-160 for treating rheumatoid arthritis. This study will serve as the benchmark for further research on this botanical formulation. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - March 7, 2019 Category: Complementary Medicine Source Type: research
Evaluation of in vitro cell and blood compatibility and in vivo analgesic activity of plant-derived dietary supplements
ConclusionNo hemotoxicity and good cell compatibility were found for all the tested samples. GA and Eq were the best candidates for further biocompatibility testing. Moreover, GA reduced pain in the animal model. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 28, 2019 Category: Complementary Medicine Source Type: research
Scientific papers: which type would you prefer?
Publication date: Available online 20 February 2019Source: Journal of Integrative MedicineAuthor(s): Chun-song HuAbstractIt’s very important to enhance the quality of scientific papers produced by postgraduates and scholars from academic institutions. To encourage their academic and professional development, these young scientists should be encouraged to compose nonresearch articles, in addition to original research articles, including short essays, perspectives and reviews. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 21, 2019 Category: Complementary Medicine Source Type: research
Antioxidant and antihyperlipidemic activity of Costus speciosus against atherogenic diet-induced hyperlipidemia in rabbits
ConclusionThe present findings indicate that the C. speciosus rhizome possesses antiatherogenic and antioxidant properties which may provide protective effects against oxidative stress in atherosclerotic rabbits. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 13, 2019 Category: Complementary Medicine Source Type: research
Medicinal properties of Angelica archangelica root extract: cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development
ConclusionAltogether, our data show the antitumor potential of the CEAA against breast cancer cells in vitro and in vivo. Further research is necessary to better elucidate the pharmacological application of the CEAA in breast cancer therapy. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 9, 2019 Category: Complementary Medicine Source Type: research
Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress
ConclusionThe results showed the dose-dependent effects of ICA against H2O2-induced injury in vascular endothelial cells. The inhibition of GRP78, ATF4 and eIF2α protein expressions in the ERS, and the subsequent alleviation of oxidative stress damage, might be the molecular mechanism.Please cite this article as: Wang FY, Jia J, Song HH, Jia CM, Chen CB, Ma J. Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress. J Integr Med. 2019; Epub ahead of print. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - February 1, 2019 Category: Complementary Medicine Source Type: research
Impact of high-fat diet and vitamin D3 supplementation on aortic stenosis establishment in waved-2 epidermal growth factor receptor mutant mice‘
ConclusionThese results suggest that HFD and vitamin D3 supplementation have no effect in the waved-2 mice model. This model essentially mimics AR and rarely AS. Further studies are needed to find a reliable animal model of AS. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 31, 2019 Category: Complementary Medicine Source Type: research
Evidence for the efficacy and safety of herbal weight loss preparations
Publication date: Available online 30 January 2019Source: Journal of Integrative MedicineAuthor(s): Rachael Farrington, Ian F. Musgrave, Roger W. ByardAbstractRising rates of obesity across the globe have been associated with an increase in the use of herbal preparations for weight control. However, the mechanisms of action for these substances are often not known, as is the potential for interaction with other herbal preparations or prescription pharmaceutical drugs. To investigate the reported efficacy and safety of herbal weight loss preparations, we conducted a review of the literature focusing on herbs that are most c...
Source: Journal of Integrative Medicine - January 31, 2019 Category: Complementary Medicine Source Type: research
Effects of geraniin (rambutan rind extract) on blood pressure and metabolic parameters in rats fed high-fat diet
ConclusionGeraniin at lower doses improved blood pressure and other metabolic parameters. Secondary metabolites of geraniin, associated with antihypertensive activity, are relatively different to those involved in inhibiting AGE formation and increasing insulin sensitivity. The secondary metabolites of geraniin may be individually responsible for the bioactivities demonstrated. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 30, 2019 Category: Complementary Medicine Source Type: research
Chenopodium ambrosioides induces an endothelium-dependent relaxation of rat isolated aorta
ConclusionThese results suggest that the MF of C. ambrosioides produces an endothelium-dependent relaxation of the isolated rat aorta, which is thought to be mediated mainly through stimulation of the muscarinic receptors, and probably involving the opening of Ca2+-activated potassium channels. (Source: Journal of Integrative Medicine)
Source: Journal of Integrative Medicine - January 29, 2019 Category: Complementary Medicine Source Type: research
