Compositional analyses of white, brown and germinated forms of popular Malaysian rice to offer insight into the growing diet-related diseases
Publication date: April 2018Source: Journal of Food and Drug Analysis, Volume 26, Issue 2Author(s): Bilyaminu Abubakar, Hafeez Muhammad Yakasai, Norhasnida Zawawi, Maznah IsmailAbstractDiet-related metabolic diseases, and especially obesity, are metabolic disorders with multifactorial aetiologies. Diet has been a cornerstone in both the aetiology and management of this metabolic disorders. Rice, a staple food for over half of the world's population, could be exploited as part of the solution to check this menace which has been skyrocketing in the last decade. The present study investigated nine forms of rice from three wid...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Comparison of anti-inflammatory effect and protein profile between the water extracts from Formosan sambar deer and red deer
In this study, we demonstrated the difference of anti-inflammatory effect and the protein profile between SVAE and RVAE. SVAE showed better anti-inflammatory potential than RVAE. In the future, the anti-inflammatory active components and their related mechanisms should be further investigated.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Curculigoside and polyphenol-rich ethyl acetate fraction of Molineria latifolia rhizome improved glucose uptake via potential mTOR/AKT activated GLUT4 translocation
Publication date: Available online 5 April 2018Source: Journal of Food and Drug AnalysisAuthor(s): Der Jiun Ooi, Nur Hanisah Azmi, Mustapha Umar Imam, Noorjahan Banu Alitheen, Maznah IsmailAbstractAdipose tissue is one of the major organs responsible for rapid restoration of postprandial glucose fluxes. Being the major isoform of glucose transporter in adipose tissue, regulations of insulin-dependent GLUT4 trafficking have always been of research interest. The present study aimed to examine the molecular mechanisms underlying the efficacy of curculigoside and polyphenol-rich ethyl acetate fraction (EAF) of Molineria latifo...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

A novel micro-extraction strategy for extraction of bisphosphonates from biological fluids using zirconia nanoparticles coupled with spectrofluorimetry and high performance liquid chromatography
Publication date: Available online 5 April 2018Source: Journal of Food and Drug AnalysisAuthor(s): Nadereh Rahbar, Ladan Nazernezhad, Maryam Asadinezhad, Zahra Ramezani, Maryam KouchakAbstractExtraction of bisphosphonates from biological fluids is important and time consuming step in sample preparation procedure. This paper describes a simple and green sample preparation technique for dispersive micro solid phase extraction (DMSPE) of alendronate sodium (ALS) from urine and serum samples prior to direct spectrofluorimetry (DSFL) and high performance liquid chromatography with fluorescence detection (HPLC-FLD), respectively...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Profiles of commensal and opportunistic bacteria in human milk from healthy donors in Taiwan
In conclusion, each milk sample revealed a unique profile and patterns of bacterial abundance levels, and our data do not support the idea that lactobacilli and bifidobacteria are common and abundant in modern milk samples. Because none of the donors of the milk samples showed mastitis or any discomfort during the sampling process or at follow-up inspection, the microbiota of these milk samples is not likely to negatively affect its host. This study provides new information on the proportions of commensal bacteria in human milk in Taiwan.Graphical abstractBacterial species composition in human milk samples from healthy don...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Down-regulation of partial substitution for staple food by oat noodles on blood lipid levels: A randomized, double-blind, clinical trial
Publication date: Available online 26 May 2018Source: Journal of Food and Drug AnalysisAuthor(s): Miao-Yu Liao, You-Cheng Shen, Hui-Fang Chiu, Siew-Moi Ten, Yan-Ying Lu, Yi-Chun Han, Kamesh Venkatakrishnan, Shun-Fa Yang, Chin-Kun WangAbstractThis clinical trial was conducted to assess the lipid-lowering activity of oat noodles by replacing partial staple food (wheat or rice noodle) in normal and mildly hypercholesterolemic subjects. Totally 84 healthy and mild hypercholesterolemic subjects were recruited and divided into 2 groups as experimental (oat noodles) and placebo (wheat noodles) and instructed to consume 100 g of ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

A steroidal derivative from Trigonella foenum graecum L. that induces apoptosis in vitro and in vivo
In this study, we investigated the cytotoxicity, antitumor, antimetastatic and antiangiogenic effect of the steroidal compound, ethyl iso-allocholate isolated from T. foenum graecum L. seeds against A549 lung cancer cells in vitro and in vivo. Among all the isolated compounds, the ethyl iso-allocholate rendered the highest cytotoxicity potential. It showed least percentage cell viability in trypan blue assay and lowest nuclei count in hoechst staining. The caspase glo assay and western blot analysis showed the significant caspase 3 cleavage, indicating caspase dependent apoptosis. Consistent with the in vitro data, ethy...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Application of food description to the food classification system: Evidence of risk assessment from Taiwan as Acrylamide of grain products
This study also compared the Acrylamide hazard index estimated under the HFDFC system with that under the National Food Consumption Database in Taiwan (NFCDT). The findings indicated that the HFDFC system provides useful and detailed information that helps the users to quickly identify food information in a harmonized manner and to reduce estimation bias. The HFDFC system is expected to facilitate global comparisons in the food risk assessment because it is built based upon EU Foodex2.Graphical abstract (Source: Journal of Food and Drug Analysis)
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Therapeutic effects of Lactobacillus paracasei subsp. paracasei NTU 101 powder on dextran sulfate sodium-induced colitis in mice
Publication date: Available online 31 May 2018Source: Journal of Food and Drug AnalysisAuthor(s): Chien-Li Chen, Pei-Yu Hsu, Tzu-Ming PanAbstractUlcerative colitis (UC) is a form of inflammatory bowel disease (IBD) whose exact cause is still unclear. Disruption of the intestinal microflora is considered one of the main causes of the disease. Lactobacillus paracasei subsp. paracasei NTU 101 (NTU 101) is a multifunctional strain that has been shown in previous studies to possess anti-inflammatory properties and to exert a modulatory effect on intestinal bacteria associated with certain pathogenic mechanisms of IBD. In the cu...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Multivariate optimization of mebeverine analysis using molecularly imprinted polymer electrochemical sensor based on silver nanoparticles
Publication date: Available online 6 June 2018Source: Journal of Food and Drug AnalysisAuthor(s): Azizollah Nezhadali, Golnar Ahmadi BonakdarAbstractThin film of a moleculary imprinted polymer (MIP) based on electropolymerization method with sensitive and selective binding sites for mebeverine (MEB) was developed. This film was cast on pencil graphite electrode (PGE) by electrochemical polymerization in solution of pyrrole (PY) and template MEB via cyclic voltammetry scans and further electrodeposition of silver nanoparticles (AgNPs). Several parameters controlling the performance of the silver nano particles MIP pencil gr...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Isoprenyl phenolic ethers from the termite nest-derived medicinal fungus Xylaria fimbriata
Publication date: Available online 18 June 2018Source: Journal of Food and Drug AnalysisAuthor(s): Mei-Chuan Chen, Guei-Jane Wang, Yueh-Hsiung Kuo, Yin-Ru Chiang, Ting-Yu Cho, Yu-Ming Ju, Tzong-Huei LeeAbstractSeven new isoprenyl phenolic ethers, namely fimbriethers A‒G (1‒7), were isolated from the fermented broth of the termite nest-derived medicinal fungus Xylaria fimbriata YMJ491. Their structures were determined by spectroscopic data analysis and compared with those reported. The effects of all the isolates at a concentration of 100 μM on the inhibition of nitric oxide (NO) production in lipopolysaccharide (LPS)...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Hantzsch pre-column derivatization for simultaneous determination of alendronate sodium and its pharmacopoeial related impurity: Comparative study with synchronous fluorometry using fluorescamine
Publication date: Available online 18 June 2018Source: Journal of Food and Drug AnalysisAuthor(s): Amira F. El-Yazbi, Eman I. El-Kimary, Rasha M. YoussefAbstractHigh performance liquid chromatographic (HPLC) method with a pre-column derivatization based on Hantzsch condensation reaction was applied for simultaneous determination of alendronate sodium (ALN) and its main related impurity, 4-Aminobutanoic acid (ABA) at its pharmacopeial limit. The separation of colored condensation products of ALN and ABA were achieved on Agilent Zobrax Eclipse SB-C18 analytical column (250 × 4.6 mm, 5 μm) using a mobile phase composed ...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Paper based electrochemical biosensor using haemoglobin nanoparticles for detection of acrylamide in processed foods
We describe herein the construction of an electrochemical paper based device (EPAD) for detection of acrylamide, a carcinogen and neurotoxin generated during thermal processing of foods through Maillard reaction. To achieve it, haemoglobin (Hb) nanoparticles (NPs) were prepared by desolvation method and characterized by transmission electron microscopy, UV–visible spectroscopy, X-ray diffraction and atomic force microscopy (AFM). The HbNPs were drop casted onto PAD for electrochemical detection of acrylamide. The EPAD showed the optimum response within 2 s at pH 5.5 and 20 °C. The working range of EPAD was 0.1 nM–1...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Antioxidant activity, neuroprotective properties and bioactive constituents analysis of varying polarity extracts from Eucalyptus globulus leaves
Publication date: Available online 18 June 2018Source: Journal of Food and Drug AnalysisAuthor(s): Elena González-Burgos, Mindaugas Liaudanskas, Jonas Viškelis, Vaidotas Žvikas, Valdimaras Janulis, M. Pilar Gómez-SerranillosAbstractEucalyptus globulus is employed as herbal tea and therapeutical purposes. In this work, it is investigated for first time the neuroprotective activities, based on antioxidant properties, of varying polarity extracts (acetone, ethanol and methanol) from E. globulus leaves and elucidate their main bioactive constituents. Methanol and acetone extracts contained the highest phenolic compounds a...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research

Benefits of combination low-dose pioglitazone plus fish oil on aged type 2 diabetes mice
Publication date: Available online 27 June 2018Source: Journal of Food and Drug AnalysisAuthor(s): Yuzuru Iizuka, Hyounju Kim, Satoshi Hirako, Kanako Chiba, Masahiro Wada, Akiyo MatsumotoAbstractThe elderly patients with type 2 diabetes suffer more adverse drug events than young adults due to pharmacokinetic and pharmacodynamic changes associated with aging. Reducing the risks of these medication-related problems are equally important for the clinical care of older type 2 diabetes patients. Pioglitazone is used for treating type 2 diabetes as an oral antidiabetic drug. Despite pioglitazone is used helpful insulin sensitize...
Source: Journal of Food and Drug Analysis - July 5, 2018 Category: Food Science Source Type: research