Therapeutic plasma exchange in chronic dysimmune peripheral neuropathies: A 10 ‐year retrospective study
ConclusionTPE appears to be effective in CIDP and PPN, and ineffective in Lewis‐Sumner and POEMS syndromes. Interestingly, anti‐MAG neuropathy patients showed a good rate of response to TPE. Regarding these preliminary results, a randomized trial would be very worthwhile in this disease for which there is no evidence based treatment to date. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: Philippe Codron, Maud Cousin, Jean ‐François Subra, Vivien Pautot, Franck Letournel, Christophe Verny, Julien Cassereau Tags: RESEARCH ARTICLE Source Type: research
Comparison of two double red cell collection settings on Fenwal Alyx apheresis instrument
In conclusion, the variable target efficiently allows collections of products with higher red cell volume and hemoglobin without a significant increase in collection and processing time. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: Edwin A. Burgstaler, Kimberly J. Duffy, Manish J. Gandhi Tags: RESEARCH ARTICLE Source Type: research
Pre ‐emptive plerixafor injection in lymphoma patients mobilized with chemotherapy plus pegfilgrastim followed by apheresis on the same day
(Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: E. Jantunen, A. Partanen, J. Valtola, M. Py örälä, P. Mäntymaa, T. Nousiainen, V. Varmavuo Tags: LETTER TO THE EDITOR Source Type: research
Therapeutic exchange with reconstituted whole blood using plasma exchange kit on a cell separator in G6PD deficient patient requiring red cell exchange for methemoglobinemia
(Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: Satya Prakash, Rekha Hans, Ratti Ram Sharma, Neelam Marwaha, Ritesh Agarwal Tags: LETTER TO THE EDITOR Source Type: research
Plasma exchange in the intensive care unit: Technical aspects and complications
ConclusionPlasma exchange is a relatively safe and generally well‐tolerated procedure in the ICU setting. Most adverse events are unpredictable and related to minor allergic reactions. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: Aur élie Lemaire, Nathalie Parquet, Lionel Galicier, David Boutboul, Rémi Bertinchamp, Marion Malphettes, Guillaume Dumas, Eric Mariotte, Marie‐Noëlle Peraldi, Virginie Souppart, Benoit Schlemmer, Elie Azoulay, Emmanuel Canet Tags: RESEARCH ARTICLE Source Type: research
Predictors for successful PBSC collection on the fourth day of G ‐CSF‐induced mobilization in allogeneic stem cell donors
In conclusion, PBSC collection on day 4 will not result in a successful harvest in most stem cell donors, however using a twice daily G‐CSF scheme increases the yield. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 31, 2017 Category: Hematology Authors: Anja van Oostrum, Jaap Jan Zwaginga, Sandra Croockewit, Jacqueline Overdevest, Mirjam Fechter, Bart Ruiterkamp, Anneke Brand, Tanja Netelenbos Tags: RESEARCH ARTICLE Source Type: research
Case report of male child with elevated lipoprotein (a) leading to acute ischemic stroke
Abstract
Acute ischemic stroke (AIS) in children is rare with almost 40% diagnosed as cryptogenic. One possible mechanism associated with AIS is an elevated Lipoprotein (a) [Lp(a)] level. Here, we discuss the case of an 11‐year old boy who presented with multiple thrombotic strokes secondary to elevated Lp(a), which was identified as the only risk factor and immediately treated with lipoprotein apheresis (LA). Eighteen months post‐AIS, he is still receiving LA treatments and has made remarkable progress in his recovery without another cerebrovascular event. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 30, 2017 Category: Hematology Authors: Patrick M. Moriarty, Heather Tennant, Nandhini Sehar, Lauryn Denney, Paola Luna, Francesca Perez ‐Marques, Apurva Panchal, Michael Abraham, John Leever Tags: CASE REPORT Source Type: research
G ‐CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield
Abstract
Mobilized PBSC are the main source for allogeneic HSCT. We aimed to evaluate factors that affect CD34+ cell yield including the donor's age, gender, BSA, processed blood volume and the method of G‐CSF dose calculation. Data from 170 healthy donors were analyzed. The concentration of CD34+ cells in the peripheral blood (PB) and the processed volume of blood were significantly correlated to CD34+ cells yield (P < .00005 and P < .001, respectively). The G‐CSF dose per m2 was significantly correlated to the concentration of CD34+ cells in the PB (P = .0003) and in the product (P = .01). Small...
Source: Journal of Clinical Apheresis - January 19, 2017 Category: Hematology Authors: Maciej Machaczka, Hans H ägglund, Emma Staver, Monika Joks, Moustapha Hassan, Björn Engelbrekt Wahlin, Ulla Axdorph Nygell Tags: Research Article Source Type: research
Methods for the detection and serum depletion of porcine galectin ‐3
ConclusionsMethods have been developed for the detection and depletion of porcine Gal‐3. These methods will be used to study the specific effects of Gal‐3 depletion via apheresis in porcine models of disease. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 13, 2017 Category: Hematology Authors: Isaac Eliaz, Aarti Patil, Nalu Navarro ‐Alvarez, Zhirui Wang, Amity Eliaz, Elaine Weil, Barry Wilk, David H. Sachs, Christene A. Huang Tags: Research Article Source Type: research
Issue Information
(Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - January 2, 2017 Category: Hematology Tags: Issue Information Source Type: research
Acute mechanical hemolysis as a complication of extracorporeal photopheresis in a low ‐weight child
Graft‐versus‐host disease (GVHD) is a complication of allogeneic hematopoietic stem cell transplantation with high morbidity and mortality. Extracorporeal photopheresis (ECP) is an effective therapy for treating medication‐refractory GVHD, however, there is scant evidence of whether ECP can be safely performed in patients weighing less than 15 kg. Here, we report the implementation of a successful protocol to perform ECP in a 21‐month‐old, 10.6 kg female with medication‐refractory GVHD. Our initial ECP treatment resulted in significant hemolysis that was most likely mechanical. After procedural adjustments that...
Source: Journal of Clinical Apheresis - November 28, 2016 Category: Hematology Authors: Robert A. DeSimone, Sandeep N. Wontakal, Alexander K. Lyashchenko, Joseph Schwartz Tags: Case Report Source Type: research
The impact of citrate concentration on adhesion of platelets and leukocytes to adsorbents in whole blood lipoprotein apheresis
In conclusion, citrate influences activation and adhesion of platelets and leukocytes in a concentration‐dependent manner, and ACD‐A 1:20, equivalent to a citrate concentration of 5.6 mM in whole blood, ensures minimal cellular activation during passage of whole blood over polyacrylate‐based adsorbents. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - November 17, 2016 Category: Hematology Authors: Ren é Weiss, Michael B. Fischer, Viktoria Weber Tags: Research Article Source Type: research
Plateletpheresis efficiency and mathematical correction of software ‐derived platelet yield prediction: A linear regression and ROC modeling approach
ConclusionTrima Accel v6.0 software consistently underestimated PLT yields. Simple correction derived from linear regression analysis accurately corrected this underestimation and ROC analysis identified a precise cut‐off to reliably predict a DP. (Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - November 11, 2016 Category: Hematology Authors: Jos é Carlos Jaime‐Pérez, Raúl Alberto Jiménez‐Castillo, Karina Elizabeth Vázquez‐Hernández, Rosario Salazar‐Riojas, Nereida Méndez‐Ramírez, David Gómez‐Almaguer Tags: Research Article Source Type: research
Issue Information
(Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - November 9, 2016 Category: Hematology Tags: Issue Information Source Type: research
Cover Image
(Source: Journal of Clinical Apheresis)
Source: Journal of Clinical Apheresis - November 9, 2016 Category: Hematology Tags: Issue Information Source Type: research
