Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration
t G Thorne (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 10, 2014 Category: Neurology Authors: Jeffrey J LochheadDaniel J WolakMichelle E PizzoRobert G Thorne Tags: blood–brain barrier integrative optical imaging matrix metalloproteinase-9 pharmacokinetics pial vessels Source Type: research

The effects of transit time heterogeneity on brain oxygenation during rest and functional activation
16;stergaard (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 10, 2014 Category: Neurology Authors: Peter M RasmussenSune N JespersenLeif Østergaard Tags: blood oxygen level-dependent contrast capillaries capillary transit time heterogeneity hemodynamics neurovascular coupling Source Type: research

Mapping functional connectivity using cerebral blood flow in the mouse brain
h P Culver (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 10, 2014 Category: Neurology Authors: Karla M BergonziAdam Q BauerPatrick W WrightJoseph P Culver Tags: brain imaging cortical mapping intrinsic optical imaging neurovascular coupling Source Type: research

Intravenous ethanol increases dopamine release in the ventral striatum in humans: PET study using bolus-plus-infusion administration of [11C]raclopride
Intravenous ethanol increases dopamine release in the ventral striatum in humans: PET study using bolus-plus-infusion administration of [11C]raclopride Journal of Cerebral Blood Flow & Metabolism advance online publication, December 10 2014. doi:10.1038/jcbfm.2014.209 Authors: Sargo Aalto, Kimmo Ingman, Kati Alakurtti, Valtteri Kaasinen, Jussi Virkkala, Kjell Någren, Juha O Rinne & Harry Scheinin (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 10, 2014 Category: Neurology Authors: Sargo AaltoKimmo IngmanKati AlakurttiValtteri KaasinenJussi VirkkalaKjell NågrenJuha O RinneHarry Scheinin Tags: [11C] raclopride alcohol bolus-plus-infusion dopamine ethanol positron emission tomography Source Type: research

The role of the spleen in ischemic stroke
Offner (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 3, 2014 Category: Neurology Authors: Keith R PennypackerHalina Offner Tags: brain ischemia macrophages neuroinflammation Source Type: research

L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain
ri & Takao Urabe (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 3, 2014 Category: Neurology Authors: Yuji UenoMasato KoikeYoshiaki ShimadaHideki ShimuraKenichiro HiraRyota TanakaYasuo UchiyamaNobutaka HattoriTakao Urabe Tags: axonal outgrowth chronic hypoperfusion L-carnitine oxidative stress stroke Source Type: research

Cerebral vasospasm affects arterial critical closing pressure
sos & Peter Smielewski (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - December 3, 2014 Category: Neurology Authors: Georgios V VarsosKarol P BudohoskiMarek CzosnykaAngelos G KoliasNathalie NasrJoseph DonnellyXiuyun LiuDong-Joo KimPeter J HutchinsonPeter J KirkpatrickVassilis G VarsosPeter Smielewski Tags: critical closing pressure subarachnoid hemorrhage vasospasm wall tension Source Type: research

Increased cerebrovascular sensitivity to endothelin-1 in a rat model of obstructive sleep apnea: a role for endothelin receptor B
bert M Bryan (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 26, 2014 Category: Neurology Authors: David J DurganRandy F CrosslandEric E LloydSharon C PhillipsRobert M Bryan Tags: cerebrovascular circulation endothelin-1 endothelin receptor A endothelin receptor B obstructive sleep apnea Source Type: research

Granulocyte colony-stimulating factor attenuates delayed tPA-induced hemorrhagic transformation in ischemic stroke rats by enhancing angiogenesis and vasculogenesis
p; Cesar V Borlongan (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 26, 2014 Category: Neurology Authors: Ike C dela PeñaArum YooNaoki TajiriSandra A AcostaXunming JiYuji KanekoCesar V Borlongan Tags: angiogenesis EPCs G-CSF hemorrhagic transformation tPA vasculogenesis Source Type: research

Lactate transport and signaling in the brain: potential therapeutic targets and roles in body–brain interaction
Lactate transport and signaling in the brain: potential therapeutic targets and roles in body–brain interaction Journal of Cerebral Blood Flow & Metabolism advance online publication, November 26 2014. doi:10.1038/jcbfm.2014.206 Author: Linda Hildegard Bergersen (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 26, 2014 Category: Neurology Authors: Linda Hildegard Bergersen Tags: blood–brain barrier energy metabolism exercise lactate receptors Source Type: research

The simplified reference tissue model: model assumption violations and their impact on binding potential
r N Gunn (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 26, 2014 Category: Neurology Authors: Cristian A SalinasGraham E SearleRoger N Gunn Tags: binding potential PET PRTM reference tissue models SRTM Source Type: research

Blood–brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia
Blood–brain barrier breakdown involves four distinct stages of vascular damage in various models of experimental focal cerebral ischemia Journal of Cerebral Blood Flow & Metabolism advance online publication, November 26 2014. doi:10.1038/jcbfm.2014.199 Authors: Martin Krueger, Ingo Bechmann, Kerstin Immig, Andreas Reichenbach, Wolfgang Härtig & Dominik Michalski (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 26, 2014 Category: Neurology Authors: Martin KruegerIngo BechmannKerstin ImmigAndreas ReichenbachWolfgang HärtigDominik Michalski Tags: blood–brain barrier brain ischemia focal ischemia intracerebral hemorrhage neurovascular unit Source Type: research

MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats
MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats Journal of Cerebral Blood Flow & Metabolism advance online publication, November 19 2014. doi:10.1038/jcbfm.2014.205 Authors: Gro K Povlsen & Lars Edvinsson (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 19, 2014 Category: Neurology Authors: Gro K PovlsenLars Edvinsson Tags: cerebral artery clazosentan ET-1 receptor upregulation U0126 5-CT Source Type: research

Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion
lerian E Kagan & Hülya Bayır (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 19, 2014 Category: Neurology Authors: Jing JiSophie BaartAnna S VikulinaRobert SB ClarkTamil S AnthonymuthuVladimir A TyurinLina DuClaudette M St CroixYulia Y TyurinaJesse LewisErin M SkodaAnthony E KlinePatrick M KochanekPeter WipfValerian E KaganHülya Bayır Tags: cardiac arrest cardiopulmonary resuscitation heart arrest XJB-5-131 Source Type: research

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats
erland & Karen Horsburgh (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - November 19, 2014 Category: Neurology Authors: Philip R HollandMercede A PannozzoMark E BastinAllison D McNeillyKaren J FergusonSarah CaugheyMaurits A JansenGavin D MerrifieldIan MarshallJohn J MullinsJoanna M WardlawCalum SutherlandKaren Horsburgh Tags: ageing cerebrovascular disease hypertension MRI and white matter Source Type: research