TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice
TAK-242, an antagonist for Toll-like receptor 4, protects against acute cerebral ischemia/reperfusion injury in mice Journal of Cerebral Blood Flow & Metabolism advance online publication, January 14 2015. doi:10.1038/jcbfm.2014.240 Authors: Fang Hua, Huiling Tang, Jun Wang, Megan C Prunty, Xiaodong Hua, Iqbal Sayeed & Donald G Stein (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 14, 2015 Category: Neurology Authors: Fang HuaHuiling TangJun WangMegan C PruntyXiaodong HuaIqbal SayeedDonald G Stein Tags: cerebral ischemia/reperfusion neuroprotection TAK-242 Toll-like receptors Source Type: research

Enhanced delivery and bioactivity of the neurturin neurotrophic factor through focused ultrasound—mediated blood–brain barrier opening in vivo
Enhanced delivery and bioactivity of the neurturin neurotrophic factor through focused ultrasound—mediated blood–brain barrier opening in vivo Journal of Cerebral Blood Flow & Metabolism advance online publication, January 14 2015. doi:10.1038/jcbfm.2014.236 Authors: Gesthimani Samiotaki, Camilo Acosta, Shutao Wang & Elisa E Konofagou (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 14, 2015 Category: Neurology Authors: Gesthimani SamiotakiCamilo AcostaShutao WangElisa E Konofagou Tags: blood–brain barrier drug delivery focused ultrasound neurotrophic factor neurturin Parkinson’s disease Source Type: research

Postsynaptic and spiking activity of pyramidal cells, the principal neurons in the rat hippocampal CA1 region, does not control the resultant BOLD response: a combined electrophysiologic and fMRI approach
nstein (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Thomas ScherfFrank Angenstein Tags: CA3 electrophysiology field excitatory postsynaptic potential fMRI hippocampus neurovascular coupling Source Type: research

Rewarming from therapeutic hypothermia induces cortical neuron apoptosis in a swine model of neonatal hypoxic–ischemic encephalopathy
Rewarming from therapeutic hypothermia induces cortical neuron apoptosis in a swine model of neonatal hypoxic–ischemic encephalopathy Journal of Cerebral Blood Flow & Metabolism advance online publication, January 7 2015. doi:10.1038/jcbfm.2014.245 Authors: Bing Wang, Jillian S Armstrong, Jeong-Hoo Lee, Utpal Bhalala, Ewa Kulikowicz, Hui Zhang, Michael Reyes, Nicole Moy, Dawn Spicer, Junchao Zhu, Zeng-Jin Yang, Raymond C Koehler, Lee J Martin & Jennifer K Lee (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Bing WangJillian S ArmstrongJeong-Hoo LeeUtpal BhalalaEwa KulikowiczHui ZhangMichael ReyesNicole MoyDawn SpicerJunchao ZhuZeng-Jin YangRaymond C KoehlerLee J MartinJennifer K Lee Tags: asphyxia heart arrest hypothermia neuronal cell death newborn rewarming Source Type: research

Characterization of blood flow in the mouse dorsal spinal venous system before and after dorsal spinal vein occlusion
B Schaffer (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Matthew J FarrarJonathan D RubinDarcy M DiagoChris B Schaffer Tags: in vivo imaging microvascular networks spinal cord blood flow two photon excited fluorescence microscopy venous occlusion Source Type: research

Blood flow distribution in cerebral arteries
und & Jan Malm (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Laleh ZarrinkoobKhalid AmbarkiAnders WåhlinRichard BirganderAnders EklundJan Malm Tags: aging cerebral blood flow circle of Willis cognitive impairment phase-contrast MRI stroke Source Type: research

Mast cells promote blood brain barrier breakdown and neutrophil infiltration in a mouse model of focal cerebral ischemia
Carswell (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Craig M McKittrickCatherine E LawrenceHilary V O Carswell Tags: blood brain barrier brain edema focal ischemia inflammation reperfusion Source Type: research

Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke
Noriko Salamon & Danny JJ Wang (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Songlin YuDavid S LiebeskindSumit DuaHolly WilhalmeDavid ElashoffXin J QiaoJeffry R AlgerNerses SanossianSidney StarkmanLatisha K AliFabien ScalzoXin LouBryan YooJeffrey L SaverNoriko SalamonDanny JJ Wang Tags: arterial spin labeling (ASL) acute ischemic stroke (AIS) hemorrhagic transformation (HT) hyperperfusion Source Type: research

Reference region modeling approaches for amphetamine challenge studies with [11C]FLB 457 and PET
Reference region modeling approaches for amphetamine challenge studies with [11C]FLB 457 and PET Journal of Cerebral Blood Flow & Metabolism advance online publication, January 7 2015. doi:10.1038/jcbfm.2014.237 Authors: Christine M Sandiego, Jean-Dominique Gallezot, Keunpoong Lim, Jim Ropchan, Shu-fei Lin, Hong Gao, Evan D Morris & Kelly P Cosgrove (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Christine M SandiegoJean-Dominique GallezotKeunpoong LimJim RopchanShu-fei LinHong GaoEvan D MorrisKelly P Cosgrove Tags: amphetamine challenge C-11 FLB 457 D2/D3 receptors extrastriatal dopamine PET reference region Source Type: research

Unexpected complication in a rat stroke model: exacerbation of secondary pathology in the thalamus by subacute intraarterial administration of human bone marrow-derived mesenchymal stem cells
Jukka Jolkkonen (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Bhimashankar MitkariErja KerkeläJohanna NystedtMatti KorhonenJukka Jolkkonen Tags: β-amyloid calcium cell therapy cerebral ischemia secondary pathology Source Type: research

In memoriam: William Feindel, O.C., G.O.Q., MDCM, D. Phil; July 12, 1918—January 12, 2014
In memoriam: William Feindel, O.C., G.O.Q., MDCM, D. Phil; July 12, 1918—January 12, 2014 Journal of Cerebral Blood Flow & Metabolism advance online publication, January 7 2015. doi:10.1038/jcbfm.2014.234 Authors: Mirko Diksic & Victor Swoboda (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Mirko DiksicVictor Swoboda Source Type: research

Neurochemical and BOLD responses during neuronal activation measured in the human visual cortex at 7 Tesla
Lynn E Eberly & Silvia Mangia (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Petr BednaříkIvan TkáčFederico GioveMauro DiNuzzoDinesh K DeelchandUzay E EmirLynn E EberlySilvia Mangia Tags: Functional Spectroscopy GABA quantification Neurochemistry Visual Stimulation Source Type: research

Effects of a high-caloric diet and physical exercise on brain metabolite levels: a combined proton MRS and histologic study
ang Weber-Fahr, Johannes Fuss & Peter Gass (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Matthias K AuerMarkus SackJenny N LenzMira JakovcevskiSarah V BiedermannClaudia Falfán-MelgozaJan DeussingJörg SteinleMaximilian BielohubyMartin BidlingmaierFrederik PfisterGünter K StallaGabriele EndeWolfgang Weber-FahrJohannes FussPeter Gass Tags: diabetes exercise 1HMRS inflammation obesity spectroscopy Source Type: research

The relationship between glucose metabolism, resting-state fMRI BOLD signal, and GABAA-binding potential: a preliminary study in healthy subjects and those with temporal lobe epilepsy
m H Theodore (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Allison C NugentAshley MartinezAlana D'AlfonsoCarlos A ZarateWilliam H Theodore Tags: functional connectivity GABA glucose metabolism glutamate resting state temporal lobe epilepsy Source Type: research

Simvastatin restored vascular reactivity, endothelial function and reduced string vessel pathology in a mouse model of cerebrovascular disease
Hamel (Source: Journal of Cerebral Blood Flow)
Source: Journal of Cerebral Blood Flow - January 7, 2015 Category: Neurology Authors: Xin-Kang TongEdith Hamel Tags: aging cerebrovascular fibrosis cholesterol neurovascular coupling vascular dementia Source Type: research