MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats

MEK1/2 inhibitor U0126 but not endothelin receptor antagonist clazosentan reduces upregulation of cerebrovascular contractile receptors and delayed cerebral ischemia, and improves outcome after subarachnoid hemorrhage in rats Journal of Cerebral Blood Flow & Metabolism advance online publication, November 19 2014. doi:10.1038/jcbfm.2014.205 Authors: Gro K Povlsen & Lars Edvinsson
Source: Journal of Cerebral Blood Flow - Category: Neurology Authors: Tags: cerebral artery clazosentan ET-1 receptor upregulation U0126 5-CT Source Type: research