2018 recommendations for the management of community acquired pneumonia
ABSTRACT Community-acquired pneumonia (CAP) is the leading cause of death worldwide. Despite the vast diversity of respiratory microbiota, Streptococcus pneumoniae remains the most prevalent pathogen among etiologic agents. Despite the significant decrease in the mortality rates for lower respiratory tract infections in recent decades, CAP ranks third as a cause of death in Brazil. Since the latest Guidelines on CAP from the Sociedade Brasileira de Pneumologia e Tisiologia (SBPT, Brazilian Thoracic Association) were published (2009), there have been major advances in the application of imaging tests, in etiologic investiga...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Noncompliance with the law prohibiting the sale of cigarettes to minors in Brazil: an inconvenient truth
Conclusions: Our findings raise an important public health concern and may contribute to supporting educational and surveillance measures to enforce compliance with existing anti-tobacco laws in Brazil, which have been disregarded.RESUMO Objetivo: Fornecer um cen ário atualizado do cumprimento da lei que proíbe a venda de cigarros para menores de 18 anos de idade. Métodos: Foram utilizados dados de acesso à compra de cigarros obtidos por meio de uma pesquisa de âmbito nacional, realizada em 2015, entre jovens escolares de 13 a 17 anos. Foram estimadas as proporções simples de tentativa de comprar cigarros; sucesso...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Impact of adherence to long-term oxygen therapy on patients with COPD and exertional hypoxemia followed for one year
Conclusions: Quality of life appears to be lower in patients with COPD and exertional hypoxemia who do not adhere to LTOT than in those who do. In addition, LTOT appears to have a beneficial effect on COPD symptoms (as assessed by SGRQ scores). (Brazilian Registry of Clinical Trials - ReBEC; identification number RBR-9b4v63 [http://www.ensaiosclinicos.gov.br])RESUMO Objetivo: Determinar o impacto da ades ão à oxigenoterapia de longa duração (OLD) na qualidade de vida, dispneia e capacidade de exercício em pacientes com DPOC e hipoxemia decorrente do esforço acompanhados durante um ano. Métodos: Foram incluídos no...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

The patient profile of individuals with Alpha-1 antitrypsine gene mutations at a referral center in Brazil
Conclusions: Our patients presented a high frequency of emphysema, bronchiectasis and bronchial thickening, and early-beginning respiratory symptoms. The most frequent genotype was Pi*ZZ. Heterozygous genotypes and normal levels of A1AT also manifested significant lung disease.RESUMO Objetivo: Caracteriza ção clínica, funcional, radiológica e genotípica dos pacientes portadores de mutações do gene da alfa-1 antitripsina (A1AT) em um centro de referência em doença pulmonar obstrutiva crônica (DPOC) no Brasil. Métodos: Estudo transversal de pacientes com mutação no gene da A1AT compatíve l com deficiência. F...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Does methylene blue attenuate inflammation in nonischemic lungs after lung transplantation?
Conclusions: MB is an effective drug for the protection of nonischemic lungs against inflammation and apoptosis following unilateral lung transplantation in rats.RESUMO Objetivo: Avaliar se o azul de metileno (AM) pode minimizar os efeitos da les ão de isquemia-reperfusão sobre o pulmão não isquêmico em um modelo de transplante pulmonar em roedores. Métodos: Quarenta ratas Sprague-Dawley foram divididas em 20 doadoras e 20 receptoras. As 20 ratas receptoras foram divididas em dois grupos (n = 10) de acordo com o tratamento (solução salina a 0,9% vs. AM a 1%). Todos os animais foram submetidos a transplante pulmon...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Functional capacity measurement: reference equations for the Glittre Activities of Daily Living test
Conclusions: The reference equations for the time to complete the Glittre ADL-test were based on a ge, BMI, and height as independent variables and can be useful for predicting the performance of adult individuals. The predicted values appear to be reliable when applied to COPD patients.RESUMO Objetivo: Elaborar equa ções de referência para o teste Glittre Activities of Daily Living (Glittre ADL) com base em variáveis antropométricas e demográficas em indivíduos aparentemente saudáveis. O objetivo secundário foi determinar a confiabilidade das equações em uma amostra composta por pacientes com DPOC. Métodos: ...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Electronic cigarette awareness and use among students at the Federal University of Mato Grosso, Brazil
Conclusions: A high proportion of university students were aware of e-cigarettes. Al though the prevalence of those who had experimented with e-cigarettes was low, there is concern that there could be an increase in the use of these types of device. There is a need for measures targeting university students, in order to build awareness of and prevent e-cigarette use.RESUMO Objetivo: Analisar a preval ência do conhecimento e experimentação do cigarro eletrônico (CE) entre universitários, bem como as características associadas ao conhecimento desse tipo de dispositivo. Métodos: Estudo transversal, utilizando-se ques...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Theoretical pneumococcal vaccine coverage: analysis of serotypes isolated from inpatients at a tertiary care hospital
Conclusions: If the patients in this sample had been previously vaccinated with PCV13 plus PPV23, theoretically, 50.8% of the cases of invasive pneumococcal disease that required hospital admission could potentially have been prevented. Invasive pneumococcal disease should be prevented by vaccination not only of children and the elderly but also of adults in their economically productive years, so as to reduce the socioeconomic costs, morbidity, and mortality s till associated with the disease, especially in underdeveloped countries.RESUMO Objetivo: Avaliar os sorotipos de Streptococcus pneumoniae isolados de uma popula Ã...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Asthma mortality in Brazil, 1980-2012: a regional perspective
Conclusions: Asthma mortality rates in Brazil have been decreasing slightly, with the decrease being more marked in the decade 2002-2012. Only the northeastern region of Brazil showed the opposite trend. Asthma mortality rates in urban and rurban Brazil showed a downward trend similar to that of the national scenario, whereas rural Brazil showed the opposite behavior. Analysis by age group showed that rates decreased among younger individuals and increased among the elderly aged ≥ 75 years.RESUMO Objetivo: Estimar as taxas de mortalidade por asma no Brasil no per íodo de 1980-2012. Métodos: A partir dos dados do Sis...
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Meeting the assumptions of statistical tests: an important and often forgotten step to reporting valid results
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Paravertebral mass
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

A importância de fundamentos robustos em metodologia científica
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Global TB Network: working together to eliminate tuberculosis
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Electronic cigarettes - the new playbook and revamping of the tobacco industry
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research

Getting to know our pneumococcus
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - December 12, 2018 Category: Respiratory Medicine Source Type: research