Estimated rates of recurrence, cure, and treatment abandonment in patients with pulmonary tuberculosis treated with a four-drug fixed-dose combination regimen at a tertiary health care facility in the city of Rio de Janeiro, Brazil
Conclusions: The adoption of the RHZE/FDC regimen produced no statistically significant differences in the rates of recurrence, cure, or treatment abandonment; nor did it have any effect on the occurrence of adverse effects, in comparison with the use of the RHZ regimen.RESUMO Objetivo: Estimar as taxas de recidiva, cura e abandono de tratamento em pacientes com tuberculose pulmonar tratados com o esquema de dose fixa combinada (DFC) de quatro drogas e avaliar poss íveis fatores associados. Métodos: Estudo observacional retrospectivo com 208 pacientes com diagnóstico confirmado de tuberculose pulmonar registrados no P...
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Tuberculosis recurrence in a priority city in the state of São Paulo, Brazil
Conclusions: A low level of education might translate to poor treatment adherence, which impedes the killing of bacilli and facilitates their survival in a latent state, making it appear as if the treatment was effective. Minimal or no weight gain at completion of the initial treatment might be a reliable biomarker to be used by health care facilities that provide tuberculosis treatment.RESUMO Objetivo: Descrever os casos de recorr ência de tuberculose (RTB) e identificar possíveis preditores segundo a classificação RTB recente ou tardia. Métodos: Estudo epidemiológico observacional analítico retrospectivo a parti...
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Spontaneous pneumomediastinum: experience in 18 patients during the last 12 years
Conclusions: Although SPM is a rare condition, it should be considered in the differential diagnosis of chest pain and dyspnea. It can develop without a triggering event or conclusive findings on a chest X-ray, which is usually sufficient for diagnosis.RESUMO Objetivo: Caracterizar clinicamente todos os pacientes com pneumomediastino espont âneo (PME) admitidos em uma enfermaria de pneumologia para adultos em Lisboa, Portugal. Métodos: Estudo descritivo retrospectivo no qual foram analisados todos os pacientes adultos ( ≥ 18 anos de idade) com diagn óstico de PME entre janeiro de 2004 e setembro de 2015. Resultado...
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
A murine model of elastase- and cigarette smoke-induced emphysema
Conclusions: Our model of emphysema induced by a combination of PPE instillation and CS exposure results in a significant degree of parenchymal destruction in a shorter time frame than that employed in other models of CS-induced emphysema, reinforcing the importance of protease-antiprotease imbalance and oxidant-antioxidant imbalance in the pathogenesis of emphysema.RESUMO Objetivo: Descrever um modelo murino de enfisema induzido por exposi ção a fumaça de cigarro (FC) e instilação de elastase pancreática porcina (EPP). Métodos: Trinta e oito camundongos C57BL/6 foram aleatoriamente divididos em quatro grupos: con...
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Influence of the ventilatory mode on acute adverse effects and facial thermography after noninvasive ventilation
Conclusions: The use of BiPAP mode was associated with a higher incidence and intensity of NIV-related acute adverse effects. There was an association between acute adverse effects and less cooling of the nasal dorsum immediately after removal of the mask. Cutaneous thermography can be an additional tool to detect adverse effects that the use of NIV has on facial skin.RESUMO Objetivo: Comparar a incid ência e a intensidade de efeitos adversos agudos e a variação da temperatura da pele da face através da termografia após a aplicação de ventilação não invasiva (VNI). Métodos: Foram incluídos 20 voluntários sad...
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Propensity scores: a tool to help quantify treatment effects in observational studies
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Multiple cavitated nodules
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
A murine model of elastase- and cigarette smoke-induced emphysema: is it an opportunity to understand CT emphysema in humans?
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Thermography as a tool for monitoring the interface between the noninvasive ventilation mask and the skin
(Source: Jornal Brasileiro de Pneumologia)
Source: Jornal Brasileiro de Pneumologia - May 19, 2017 Category: Respiratory Medicine Source Type: research
Erratum
ABSTRACT Pleuroparenchymal fibroelastosis (PPFE) is a rare lung disease. It can be idiopathic or associated with any one of various conditions. To our knowledge, this is the first report of two cases of PPFE in Brazil. Our first patient presented with pleural and subpleural fibrosis in the upper lobes; a spiculated nodule in the left upper lobe; and a mild reticular pattern in the lower lobes. Surgical lung biopsy revealed PPFE in the upper lobes, including the nodule, and unclassified interstitial pneumonia in the left lower lobe. Our second patient had a history of exposure to domestic birds, indicating a risk of hyperse...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Radial-probe EBUS for the diagnosis of peripheral pulmonary lesions
ABSTRACT Pleuroparenchymal fibroelastosis (PPFE) is a rare lung disease. It can be idiopathic or associated with any one of various conditions. To our knowledge, this is the first report of two cases of PPFE in Brazil. Our first patient presented with pleural and subpleural fibrosis in the upper lobes; a spiculated nodule in the left upper lobe; and a mild reticular pattern in the lower lobes. Surgical lung biopsy revealed PPFE in the upper lobes, including the nodule, and unclassified interstitial pneumonia in the left lower lobe. Our second patient had a history of exposure to domestic birds, indicating a risk of hyperse...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Pleuroparenchymal fibroelastosis: report of two cases in Brazil
ABSTRACT Pleuroparenchymal fibroelastosis (PPFE) is a rare lung disease. It can be idiopathic or associated with any one of various conditions. To our knowledge, this is the first report of two cases of PPFE in Brazil. Our first patient presented with pleural and subpleural fibrosis in the upper lobes; a spiculated nodule in the left upper lobe; and a mild reticular pattern in the lower lobes. Surgical lung biopsy revealed PPFE in the upper lobes, including the nodule, and unclassified interstitial pneumonia in the left lower lobe. Our second patient had a history of exposure to domestic birds, indicating a risk of hyperse...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Primary epithelioid angiosarcoma of the chest wall complicating calcified fibrothorax and mimicking empyema necessitates
ABSTRACT In patients with severe respiratory failure, either hypoxemic or hypercapnic, life support with mechanical ventilation alone can be insufficient to meet their needs, especially if one tries to avoid ventilator settings that can cause injury to the lungs. In those patients, extracorporeal membrane oxygenation (ECMO), which is also very effective in removing carbon dioxide from the blood, can provide life support, allowing the application of protective lung ventilation. In this review article, we aim to explore some of the most relevant aspects of using ECMO for respiratory support. We discuss the history of respira...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Extracorporeal respiratory support in adult patients
ABSTRACT In patients with severe respiratory failure, either hypoxemic or hypercapnic, life support with mechanical ventilation alone can be insufficient to meet their needs, especially if one tries to avoid ventilator settings that can cause injury to the lungs. In those patients, extracorporeal membrane oxygenation (ECMO), which is also very effective in removing carbon dioxide from the blood, can provide life support, allowing the application of protective lung ventilation. In this review article, we aim to explore some of the most relevant aspects of using ECMO for respiratory support. We discuss the history of respira...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
