Dysfunctional breathing: what do we know?
ABSTRACT Dysfunctional breathing (DB) is a respiratory condition characterized by irregular breathing patterns that occur either in the absence of concurrent diseases or secondary to cardiopulmonary diseases. Although the primary symptom is often dyspnea or “ air hunger ” , DB is also associated with nonrespiratory symptoms such as dizziness and palpitations. DB has been identified across all ages. Its prevalence among adults in primary care in the United Kingdom is approximately 9.5%. In addition, among individuals with asthma, a positive diagnosis of DB is found in a third of women and a fifth of men. Although DB has...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Is a low level of education a limiting factor for asthma control in a population with access to pulmonologists and to treatment?
Conclusions: Among asthma patients with access to pulmonologists and to treatment, a low level of education does not appear to be a limiting factor for adequate asthma control.RESUMO Objetivo: Avaliar se a baixa escolaridade é um fator de risco para asma não controlada em uma população de pacientes que tem acesso a um pneumologista e ao tratamento. Métodos: Estudo transversal com pacientes com diagnóstico de asma, com idade> 10 anos, acompanhados por ao menos tr ês meses por um pneumologista em ambulatórios na cidade de Jundiaí (SP). Os indivíduos responderam a um questionário específico do estudo, ao Ques...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Prevalence of vitamin D deficiency and its relationship with factors associated with recurrent wheezing
Conclusions: The prevalence of vitamin D deficiency/insufficiency was high in our sample. Vitamin D concentrations were directly associated with vitamin D supplementation until 2 years of age and were inversely associated with wheezing events in the first year of life, personal history of atopic dermatitis, and environmental pollution.RESUMO Objetivo: Determinar a preval ência da deficiência/insuficiência de vitamina D em indivíduos com sibilância recorrente e/ou asma com idade de 0-18 anos e residentes na microrregião de Viçosa (MG) atendidos em um centro de referência e determinar sua associação com os princi...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Back to the future: a case series of minimally invasive repair of pectus excavatum with regular instruments
Conclusions: In this preliminary study, the rate of complications associated with MIRPERI was comparable to that reported in the literature for MIRPE. The MIRPERI approach has the potential to improve the safety of PE repair, particularly for surgeons that do not have access to certain special instruments or have not been trained in their use.RESUMO Objetivo: O minimally invasive repair of pectus excavatum (MIRPE, reparo minimamente invasivo do pectus excavatum) é um tratamento cirúrgico do PE. Durante o procedimento, utiliza-se um introdutor específico a fim de criar um túnel mediastinal para a colocação toracoscó...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea and quality of life in elderly patients with a pacemaker
Conclusions: In elderly patients with a pacemaker, OSA was not found to be associated with quality of life or with symptoms of anxiety or depression.RESUMO Objetivo: Avaliar a qualidade de vida em idosos portadores de marca-passo e apneia obstrutiva do sono (AOS). M étodos: Estudo de corte transversal com idosos (idade ≥ 60 anos) portadores de marca-passo card íaco. A variável dependente foi qualidade de vida, avaliada por meio do Medical Outcomes Study 36-item Short-Form Health Survey (SF-36). Dados sociodemográficos e clínicos foram analisados como variáveis independentes, entre os quais ansiedade e depressão...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Management of COPD within the Brazilian Unified Health Care System in the state of Bahia: an analysis of real-life medication use patterns
Conclusions: Long-acting bronchodilators are frequently underused in individuals with moderate to very severe COPD within the Brazilian Unified Health Care System in the state of Bahia. Most patients in our sample were treated inappropriately, and undertreatment predominated. Strategies to improve access to long-acting bronchodilators and the quality of COPD pharmacological management are required.RESUMO Objetivo: Descrever o padr ão de tratamento farmacológico da DPOC no estado da Bahia e avaliar a conformidade desse padrão com diretrizes clínicas de manejo da doença. Métodos: Estudo de corte transversal envolvend...
Source: Jornal Brasileiro de Pneumologia - February 11, 2019 Category: Respiratory Medicine Source Type: research

Erratum
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Empyema caused by infection with Clostridium septicum in a patient with lung cancer
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Near-fatal pulmonary embolism: capnographic perspective
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Eosinophilic pneumonia: remember topical drugs as a potential etiology
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Pulmonary involvement in Crohn’s disease
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Obesity hypoventilation syndrome: a current review
ABSTRACT Obesity hypoventilation syndrome (OHS) is defined as the presence of obesity (body mass index ≥ 30 kg/m ²) and daytime arterial hypercapnia (PaCO2 ≥ 45 mmHg) in the absence of other causes of hypoventilation. OHS is often overlooked and confused with other conditions associated with hypoventilation, particularly COPD. The recognition of OHS is important because of its high prevalence and the fact that, if left untreated, it is associated with high morbidity and mortality. In the present review, we address recent advances in the pathophysiology and management of OHS, the usefulness of determination of venous...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Proportional weight loss in six months as a risk factor for mortality in stage IV non-small cell lung cancer
Conclusions: WL in the 6 months preceding the diagnosis of NSCLC is a relevant prognostic factor and appears to be directly proportional to the rate of survival at 3 months.RESUMO Objetivo: Avaliar diferentes pontos de corte da perda de peso (PP) como marcadores progn ósticos de sobrevida em 3 meses após o diagnóstico de câncer de pulmão de células não pequenas estádio IV (CPCNP). Métodos: Estudo prospectivo envolvendo 104 pacientes com CPCNP metastático (estádio IV) que foram internados em um centro de tratamento de câncer no sul do Brasil entre jan eiro de 2014 e novembro de 2016. Avaliamos a PP total e PP ...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Genetic and phenotypic traits of children and adolescents with cystic fibrosis in Southern Brazil
Conclusions: The mutations of CFTR identified more frequently were F508del and G542X. These are type II and I mutations, respectively. Along with type III, they present a more severe cystic fibrosis phenotype. More than half of the sample (52.38%) presented homozygous mutation for F508del, that is, patients who could be treated with Lumacaftor/Ivacaftor. Approximately 7% of the patients (7.14%) presented type III and IV mutations, therefore becoming candidates for the treatment with Ivacaftor.RESUMO Objetivos: Caracterizar as principais muta ções identificadas no cystic fibrosis transmembrane conductance regulator (CFTR...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research

Trend of self-reported asthma prevalence in Brazil from 2003 to 2013 in adults and factors associated with prevalence
Discussion: PNAD and PNS surveys allow for a very large, representative community-based sample of the Brazilian adults to investigate the asthma prevalence. From 2003 to 2013, the prevalence of self-reported physician diagnosis of asthma increased, especially in the North and Northeast regions. Gender, region of residence, household location (urban/rural), obesity, and depression diagnosis seem to play significant roles in the epidemiology of asthma in Brazil.RESUMO Objetivos: Determinar a tend ência da prevalência de diagnóstico de asma autorreferida e descrever os fatores associados à asma em adultos brasileiros. M...
Source: Jornal Brasileiro de Pneumologia - January 31, 2019 Category: Respiratory Medicine Source Type: research