Respiratory manifestations in late-onset Pompe disease: a case series conducted in Brazil
Conclusions: In this case series, the time from symptom onset to diagnosis was long. Although respiratory signs or symptoms were not the initial manifestations of the disease, 66.7% of the patients showed reduced FVC% in the sitting and supine positions at diagnosis.RESUMO Objetivo: Descrever a fun ção respiratória em uma série de pacientes com doença de Pompe de início tardio após o diagnóstico definitivo e antes do início do tratamento através de terapia de reposição enzimática. Métodos: Estudo transversal em pacientes com diagnóstico molecular de doença de Pompe de início tardio. As informações ...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Association of tuberculosis with multimorbidity and social networks
ABSTRACT The combination of tuberculosis with other diseases can affect tuberculosis treatment within populations. In the present study, social network analysis of data retrieved from the Mexican National Epidemiological Surveillance System was used in order to explore associations between the number of contacts and multimorbidity. The node degree was calculated for each individual with tuberculosis and included information from 242 contacts without tuberculosis. Multimorbidity was identified in 49.89% of individuals. The node degrees were highest for individuals with tuberculosis + HIV infection (p< 0.04) and lowest fo...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Phenotypes of asthma in low-income children and adolescents: cluster analysis
Conclusions: Asthma was characterized by the presence of atopy, number of exacerbations, and lung function in low-income children and adolescents in Brazil. The many similarities with previous cluster analyses of phenotypes indicate that this approach shows good generalizability.RESUMO Objetivo: Estudos que caracterizam fen ótipos de asma predominantemente incluem adultos ou foram realizados em crianças e adolescentes de países desenvolvidos; portanto, sua aplicabilidade em outras populações, tais como as de países em desenvolvimento, permanece indeterminada. Nosso objetivo foi determinar como crianças e adolesc ...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Impaired pulmonary function after treatment for tuberculosis: the end of the disease?
Conclusions: Nearly half of all tuberculosis patients evolve to impaired pulmonary function. That underscores the need for pulmonary function testing after the end of treatment.RESUMO Objetivo: Avaliar a preval ência de alterações da função pulmonar e investigar os fatores que afetam a função pulmonar em pacientes tratados para tuberculose pulmonar. Métodos: Um total de 214 pacientes consecutivos (132 homens e 82 mulheres; 20-82 anos de idade), tratados para tuberculose pulmonar e acompanhados em um dispensário local, foi submetido a espirometria e pletismografia pelo menos um ano após o tratamento. Result...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
Diaphragmatic mobility: relationship with lung function, respiratory muscle strength, dyspnea, and physical activity in daily life in patients with COPD
Conclusions: In patients with COPD, diaphragmatic mobility seems to be associated with airway obstruction and lung hyperinflation, as well as with ventilatory capacity and the perception of dyspnea, although not with PADL.RESUMO Objetivo: Avaliar a rela ção da mobilidade diafragmática com a função pulmonar, força muscular respiratória, dispneia e atividade física de vida diária (AFVD) em pacientes com DPOC. Métodos: Foram avaliados 25 pacientes com diagnóstico de DPOC, classificados de acordo com critérios da Global Initiative for Chr onic Obstructive Lung Disease, e 25 indivíduos saudáveis. Todos foram ...
Source: Jornal Brasileiro de Pneumologia - April 3, 2017 Category: Respiratory Medicine Source Type: research
