Rapidly Enlarging Midline Neck Mass
A woman in her 60s was referred for evaluation of a rapidly growing thyroid goiter that coincided with the development of dysphagia, orthopnea, and hoarseness. She denied any constitutional symptoms of hypothyroidism or hyperthyroidism and had no history of irradiation. … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 31, 2014 Category: Cancer & Oncology Authors: Ozan B. Ozgursoy, MD and colleagues Tags: Clinical Problem Solving Clinical Review & Education JAMA Otolaryngology—Head & Neck Surgery Source Type: research

Availability of Tanning Beds on US College Campuses
Importance  Indoor tanning is widespread among young adults in the United States despite evidence establishing it as a risk factor for skin cancer. The availability of tanning salons on or near college campuses has not been formally evaluated. Objective  To … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 31, 2014 Category: Cancer & Oncology Authors: Sherry L. Pagoto, PhD and colleagues Tags: JAMA Dermatology Original Investigation Research Source Type: research

Computer-Aided Detection in Mammography
Since 2001, Medicare has reimbursed computer-aided detection (CAD) during screening mammography. The CAD software tool is used by radiologists to identify lesions suggestive of malignant disease. Research suggests that CAD use increases the rate of false-positive findings of screening mammography … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 31, 2014 Category: Cancer & Oncology Authors: Joshua J. Fenton, MD, MPH Tags: JAMA Internal Medicine Research Research Letter Source Type: research

Follicular Variant of Papillary Thyroid Carcinoma
Importance  The follicular variant (FV) of papillary thyroid carcinoma (PTC) is an important subtype that can be difficult to diagnose using preoperative cytologic analysis. Objective  To compare conventional and FV PTC with regard to preoperative cytologic diagnosis using a tiered … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 24, 2014 Category: Cancer & Oncology Authors: Patrick Sheahan, MB, FRCSI (ORL-HNS) and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research

Conjunctival Melanoma
The pigmented conjunctival lesion was outlined with blue ink, and subconjunctival lidocaine injected to elevated the lesion. Absolute alcohol was used to loosen the corneal epithelium, and the corneal margin scored with a crescent blade. The lesion was excised using … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 24, 2014 Category: Cancer & Oncology Authors: Glenn Yiu, MD, PhD and colleagues Tags: Clinical Review & Education JAMA Ophthalmology Ophthalmic Images Source Type: research

Middle Ear Mass With Facial Weakness
A woman in her 70s presented for evaluation of a 3-month history of intermittent left-sided facial weakness associated with otalgia and facial pain. The patient also noted occasional left-sided facial twitching and mild imbalance during this time frame. Physical examination … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 24, 2014 Category: Cancer & Oncology Authors: Gregg W. Schmedes, MD and colleagues Tags: Clinical Problem Solving Clinical Review & Education JAMA Otolaryngology—Head & Neck Surgery Source Type: research

Vismodegib for Locally Advanced Basal Cell Carcinoma in a Heart Transplant Patient
Importance  Immunosuppressed patients with solid organ transplants have an increased risk for nonmelanoma skin cancer. Vismodegib has been reported to be effective for select locally advanced or metastatic basal cell carcinomas. However, there is no data documenting the use and … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 24, 2014 Category: Cancer & Oncology Authors: Carrie Ann Cusack, MD and colleagues Tags: Case Report/Case Series JAMA Dermatology Research Source Type: research

Variation in Readmission by Hospital After Colorectal Cancer Surgery
Importance  Hospital readmission after colorectal surgery is common, with reported 30-day readmission rates ranging from 10% to 14%. Readmission has become a major hospital quality metric, but it is unclear whether there is much difference in readmission among hospitals after … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 24, 2014 Category: Cancer & Oncology Authors: Donald J. Lucas, MD, MPH and colleagues Tags: JAMA Surgery Original Investigation Research Source Type: research

Association of Sentinel Lymph Node Biopsy With Survival for Head and Neck Melanoma
Importance  Sentinel lymph node biopsy (SLNB) provides prognostic information for melanoma; however, a survival benefit has not been demonstrated. Objective  To assess the association of SLNB with survival for melanoma arising in head and neck subsites (HNM). Design, Setting, and … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 21, 2014 Category: Cancer & Oncology Authors: Steven M. Sperry, MD and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research

Rapid Involution of Choroidal Metastasis Secondary to Renal Cell Carcinoma With Oral Sunitinib
Oral sunitinib malate (Sutent) is a tyrosine kinase inhibitor that prevents binding of vascular endothelial growth factor and platelet-derived growth factor to their native receptors. It has been approved by the US Food and Drug Administration for the treatment of renal … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 21, 2014 Category: Cancer & Oncology Authors: Eric K. Chin, MD and colleagues Tags: JAMA Ophthalmology Observation Research Source Type: research