Learning Curve for Robot-Assisted Neck Dissection in Head and Neck Cancer
Importance Robot-assisted neck dissection (RAND) for the management of regional metastases is a recently developed technique in the field of head and neck cancer that uses a robotic surgical system. This is the first report that estimates the learning curve … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Won Shik Kim, MD and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research
Breast Conservation Surgery and the Definition of Adequate Margins
The definition of a sufficient margin after attempted breast conservation surgery for breast cancer has been a hotly debated topic for decades. Although there has been widespread acceptance that breast conservation surgery confers an equivalent survival outcome to mastectomy in … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Julie A. Margenthaler, MD and Aislinn Vaughan, MD Tags: Invited Commentary JAMA Surgery Opinion Source Type: research
Worry About Developing Melanoma in the Pigmented Lesion Clinic
n this issue Moye and colleagues examine psychological distress in patients with atypical mole syndrome attending a pigmented lesion clinic (PLC) who are receiving biannual total body skin examination using total body digital photography (TBDP). The authors propose that TBDP, which … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Jennifer L. Hay, PhD Tags: Editorial JAMA Dermatology Opinion Source Type: research
Repeat Surgery After Breast Conservation for the Treatment of Stage 0 to II Breast Carcinoma
Importance Although complete excision of breast cancer is accepted as the best means to reduce local recurrence and thereby improve survival, there is currently no standard margin width for breast conservation surgery. As a result, significant variability exists in the … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Lee G. Wilke, MD and colleagues Tags: JAMA Surgery Original Investigation Research Source Type: research
Specialized Surveillance for Individuals at High Risk for Melanoma
Importance Regular surveillance of individuals at high risk for cutaneous melanoma improves early detection and reduces unnecessary excisions; however, a cost analysis of this specialized service has not been undertaken. Objective To determine the mean cost per patient of surveillance … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Caroline G. Watts, MPH and colleagues Tags: JAMA Dermatology Original Investigation Research Source Type: research
Feeding Tube Placement in Patients With Advanced Cancer
A woman in her 70s presented to our hospital with progressive pain and weight loss after having recently received a diagnosis of widely metastatic lung adenocarcinoma. At admission, it was noted that she was frail and cachectic with a body … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Chelsea Bowman, MD and Eric Widera, MD Tags: JAMA Internal Medicine Opinion Perspective Source Type: research
The Withdrawal of Drugs for Commercial Reasons
This Viewpoint uses manufacturer withdrawal of tositumomab as an illustration of deficiencies in current standards of drug development and post-marketing evaluation. (Source: JAMA Oncology)
Source: JAMA Oncology - November 13, 2014 Category: Cancer & Oncology Authors: Vinay Prasad, MD Tags: Featured Opinion JAMA Internal Medicine Viewpoint Source Type: research
Sargramostim and Ipilimumab for Metastatic Melanoma
This randomized trial comparing ipilimumab with sargramostim to ipilimumab alone reports longer overall survival and lower toxicity but no difference in progression-free survival in patients with unresectable stage III or IV melanoma. (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: F. Stephen Hodi, MD and colleagues Tags: Featured Research JAMA Original Investigation Source Type: research
Sites of Origin of Oral Cavity Cancer in Nonsmokers vs Smokers
Importance The relatively high and possibly rising incidence of mouth squamous cell carcinoma in nonsmokers, especially women, without obvious cause has been noted by previous authors. Is chronic dental trauma and irritation a carcinogen, and what is its importance compared … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Brendan J. Perry, BSc, MBBS and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research
Breast Cancer Following Ovarian Cancer in BRCA Mutation Carriers
Importance BRCA mutation carriers are at increased risk of developing breast cancer. However, the incidence of breast cancer after a diagnosis of epithelial ovarian cancer (EOC), one of the tubal/peritoneal cancers collectively referred to as pelvic serous carcinomas, is not … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Alexandra Gangi, MD and colleagues Tags: JAMA Surgery Original Investigation Research Source Type: research
Early Signs of Pancreatic Cancer
Scientists who analyzed blood samples collected over time from 1500 participants in large prospective studies reported that elevated levels of branched-chain amino acids were linked with increased odds of developing pancreatic cancer (Mayers JR et al. Nat Med. doi:10.1038/nm.3686 [published … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Tracy Hampton, PhD Tags: JAMA Lab Reports Medical News & Perspectives Source Type: research
JAMA Oncology—A New Member of The JAMA Network Family of Journals
Over the next 2 decades the number of patients worldwide newly diagnosed with cancer is expected to increase from 14 million to 22 million annually and the number of annual cancer deaths globally is predicted to increase from 8.2 million … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Mary L. Disis, MD, Thomas J. Easley, and Howard Bauchner, MD Tags: Editorial JAMA Opinion Source Type: research
Neoplasms Misdiagnosed as “Chronic Lyme Disease”
Clinical features of Lyme disease include erythema migrans rash, facial palsy, arthritis, and peripheral neuropathy. In endemic areas, patients with erythema migrans can be diagnosed clinically. Otherwise, diagnosis is based on the history of possible exposure, compatible clinical features, and … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Christina Nelson, MD, MPH and colleagues Tags: JAMA Internal Medicine Research Research Letter Source Type: research
PSA Screening—I Finally Won!
I must have won. That is what everyone tells me. At the beginning there were a few telephone calls, followed by e-mails, and now every talk I give someone brings up how happy I must feel for winning. What I … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - November 6, 2014 Category: Cancer & Oncology Authors: Dan Merenstein, MD Tags: JAMA Internal Medicine Opinion Perspective Source Type: research
Importance of Tumor Grade in Esthesioneuroblastoma Survival
Importance There is a need for larger studies characterizing the effect of tumor grade on survival for patients with esthesioneuroblastoma. Objective To investigate prognostic factors for survival in patients diagnosed with esthesioneuroblastoma, including emphasis on tumor grade. Design, Setting, and … Continued (Source: JAMA Oncology)
Source: JAMA Oncology - October 31, 2014 Category: Cancer & Oncology Authors: Bobby A. Tajudeen, MD and colleagues Tags: JAMA Otolaryngology—Head & Neck Surgery Original Investigation Research Source Type: research
